A5092129538- Hydrogels: synthesis, properties, applications
- Histone Deacetylase Inhibitors Research
- Cancer-related gene regulation
- Graphene and Nanomaterials Applications
- Polysaccharides Composition and Applications
- biodegradable polymer synthesis and properties
- Epigenetics and DNA Methylation
- Nanoparticle-Based Drug Delivery
Government College University, Faisalabad
2023-2024
Guar Gum has been evaluated for its importance in food and pharmaceutical industry. A blended biopolymeric hydrogel was prepared by solution casting technique using guar gum (GG), chitosan (CS), polyvinyl alcohol (PVA), chemically crosslinked with tetra orthosilicate (TEOS) impregnated methotrexate (MTX) to assess drug carrying capacity against colon cancer (HCT-116). The surface morphology, chemical bonding, hydrophilicity water absorbing were analyzed atomic force microscopy (AFM), Fourier...
Drug delivery techniques based on polymers have been investigated for their potential to improve drug solubility, reduce systemic side effects, and controlled targeted administration at infection site. In this study, we developed a co-polymeric hydrogel composed of graphene sheets (GNS), polyvinyl alcohol (PVA), chitosan (CS) that is loaded with methotrexate (MTX) in vitro liver cancer treatment. Fourier transform infrared spectroscopy (FTIR) atomic force microscopy (AFM) was employed check...
Protein lysine methylation is a post-translational modification (PTM) that promotes protein complex formation to regulate DNA replication, gene expression, and repair mechanisms. The Su(Var)3–9, Enhancer-of-zeste Trithorax (SET) Myeloid, Nervy, DEAF-1 (MYND) domain-containing proteins SMYD are methyltransferases catalyze the of various histone non-histone proteins. There five members this family, all these have conserved SET MYND domains. domain divided into two segments by (the S-sequence...