This study was conducted to determine and recommend the most up-to-date information on indications, complications, outcomes of posterior surgical treatments for cervical spondylotic myelopathy (CSM) basis a literature review.A comprehensive search performed, using MEDLINE (PubMed), Cochrane Register Controlled Trials, Web Science databases, peer-reviewed articles published in English during last 10 years.Posterior techniques, which include laminectomy alone, with fusion, laminoplasty, are...

OBJECTIVE Global outbreak of the novel coronavirus disease 2019 (COVID-19) has forced healthcare systems worldwide to reshape their facilities and protocols. Although not considered frontline specialty in managing COVID-19 patients, neurosurgical service training were also significantly affected. This article focuses on impact at a low- and/or middle-income country (LMIC) academic tertiary referral hospital, university hospital policies actions for program during outbreak, contingency plan...

Introduction: Head injuries contribute significantly to morbidity and mortality globally, there is need of effective treatment. This study focuses on evaluating NGF (Nerve Growth Factor) expression in a rat model traumatic brain injury, exploring the potential therapeutic effects Kaempferia galanga L. extract. Methods: Male Wistar rats were used experiment, injury was induced using Marmarou's weight drop model. Four groups studied: negative control group, group with without extract, two...

Cranioplasty in pediatrics is quite challenging and intricated. The ideal material for it still debatable until now due to the limited study comparing autologous implant grafts. This meta-analytic was conducted evaluate risk of infection revision pediatric patients after autograft cranioplasty.A systematic review meta-analysis were performed according Preferred Reporting Items Systematic Reviews Meta-Analysis (PRISMA) guidelines. A thorough literature search on PubMed, Cochrane, Scopus,...

Juvenile xanthogranuloma (JXG) is a proliferative disorder of non-Langerhans histiocytes. The lesions typically occur in children as solitary cutaneous lesions, but are only rarely found adults their late twenties to thirties. Approximately 5-10% JXG extracutaneous location, with spinal being encountered. Here, we described 28-year-old male an extradural resulting severe C6- T1 cord compression and progressive quadriparesis that warranted decompressive laminectomy/C6-T2 fusion.A presented 12...

<ns4:p><ns4:bold>Background:</ns4:bold> Spinal cord injury (SCI) is a damage to the spinal caused mainly by trauma resulting in major motor, sensory and autonomic dysfunctions. Its final neurological outcome determined both primary secondary processes. A key component of mechanisms after initial neuroinflammation. neuroprotective compound, ACTH<ns4:sub>4-10</ns4:sub>Pro<ns4:sup>8</ns4:sup>-Gly<ns4:sup>9</ns4:sup>-Pro<ns4:sup>10 </ns4:sup>(ACTH<ns4:sub>4-10</ns4:sub>) also known as semax, has...

Lumbar disc herniation (LDH) is uncommon in the pediatric population. The lumbar spine biodynamics and architecture change with age, adults being more susceptible to LDH than children. When conservative treatment fails for LDH, surgery may be considered. We described an unusual instance of that was successfully treated microdiscectomy.A 15-year-old patient presented back discomfort pain her left leg had been deteriorating over 4 years. Conservative nonsteroidal anti-inflammatory medications...

Penetrated Traumatic Spinal Injury by Airgun Shot are rare events. As a result, handling this case is both, thrilling and challenging. We present of penetrated traumatic spinal injury from an airgun, as well summary the literature on how to treat them. A 9-year-old boy was taken hospital after being shot in right side his front neck with air rifle. The patient had been distance upfront direction. no breathing problem but complained pain during swallowing. conscious, alert, oriented. There...

To identify a novel material with biomechanical properties identical to the nucleus pulposus in lumbar vertebrae of goats for use intervertebral disc herniation surgery.In this laboratory-based experimental study, silicone rubber test group consisted sample compositions 35PVA65SR, 30PVA70SR, and 40PVA60SR. Axial compression mechanical tests were conducted assess resulting terms stress, strain, load, displacement.The results revealed that stress (MPa) strain (%) values 40PVA60SR closest...

The purpose of this study was to analyze the response inflammatory cytokines interleukin-8 (IL-8) and NF-κB closure skull defect with periosteum as a scaffolding material in bone healing used after surgery.Thirty Oryctolagus cuniculus rabbits underwent craniotomy create 20 mm diameter round parietal bones. bones were returned its place stabilized by an internal plate fixation. defects either left empty or implanted periosteum. At 6 weeks, specimens euthanized examined.Histological...

Background Spinal cord injury (SCI) is a significant cause of morbidity since it results in the inflammation process which leads to necrosis or apoptosis. Inflammatory response tissue damage increases IL-6 and IL-8 levels. ACTH4 - 10Pro8-Gly9-Pro10 peptide community that has been shown have beneficial effect on minimizing increasing recovery time. Methods This study true experimental laboratory research with totally randomized method. The subjects were animal models light extreme compression...

Background: Adult spinal deformity (ASD) includes spectrum heterogeneous abnormalities, which involve the lumbar or thoracolumbar segment during adulthood. In this research, age, and gender are used to describe radiological Spinal Deformity based on modified SRS-Schwab classification. Methods: This research is an observational analytical study using a cross-sectional design from AP/Lateral lumbar/lumbosacral images in 2021. Patients with adult were assessed X-ray radiology at Dr. Soetomo...

Introduction: In Indonesia, spine procedure including surgery was increasing in the current years. However, there a lack of data about it Indonesia as developing country. We collected and described all that had been done single center Klaten regency representative facilities at rural area settings. Method: This is retrospective study patients who were undergoing Department Neurosurgery Dr Soeradji Tirtonegoro Central Public hospital during period from January 2019 to December 2022. The...

Background: Neurotrophic factors such as NT-3 play an important role in spinal cord regeneration, contributing to regeneration assisting functional improvement SCI. ACTH4-10Pro8-Gly9-Pro10, analog of the N-terminal fragment (4-10) adrenocorticotropic hormone, is one neuroprotective compounds that can increase levels brain ischemia. Therefore, we conducted a study with experimental animals determine effect expression on ACTH4-10Pro8-Gly9-Pro10 administration acute compression SCI.Method: We...

Cervical spinal cord injury (SCI) is a life-threatening condition. Prompt surgical intervention needed to avoid hemodynamic and respiratory catastrophe. In Indonesia, however, spine surgery more common in tertiary hospitals thus might prolong the time gap due referral waiting time.We performed an emergency for patient with complete SCI unstable cervical fracture. The was shock experienced arrest after radiological workup. Stability achieved ICU directly sent operating theater....

The coronavirus disease 2019 (COVID-19) pandemic represents a once in century challenge to human health care with over 4.5 million cases and 300,000 deaths thus far. Surgical practice has been significantly impacted all specialties writing guidelines for how manage during this crisis. This study reported the effect of COVID-19 on neurosurgical practice, especially neurospine, outpatient visit, emergency department, surgical procedure.This is comparative retrospective about neurospine...

Background: The cervical vertebra is an important as there are blood vessels in its surroundings from the brain to entire vertebrae. Cervical injury has most fatal consequences when it occurs high C1-C2. If instability C1-C2 vertebrae and atlantoaxial joints, procedure of surgical techniques include arthrodesis or spinal fusion. C2 straight lateral mass fixation one technique that can be used for patients with cord compression anomalous vertebral artery by inserting shorter screws posterior...

Rheumatoid arthritis (RA) is an inflammatory autoimmune disease that impacts on weakening ligaments, synovial and cartilage damage. The effect can occur instability neural compression in the upper sub-axial cervical. prevalence of atlantoaxial (AAI) around 40-80% among rheumatoid patients, but it interesting to examine clinical symptoms are not so visible despite radiological confirmed cervical spine. However, once myelopathy occur, mortality rate will increase sharply. We report a case...

Spondylitis TB on cervical region is a rare disease, that may lead to severe neurological complications. The anterior approach considered as gold standard for spine tuberculosis. Available studies and literature have not precisely mentioned how many levels are acceptable this disease still up discussion.A 45-year-old Asian male was brought from rural hospital our outpatient clinic with progressive weakness of all extremities 3 months. Cervical x-ray MRI showed three-levels vertebral body...

The complications of ventriculoperitoneal (VP) shunts are many and reported in literature extensively. complication transanal extrusion after bowel perforation is known although rare. This very well described amongst the children. authors describe case a VP shunt occurring 51-year-old adult patient. patient has history craniotomy for acute subdural hematoma severe head injury one year ago continued with post-traumatic hydrocephalus. Home care bedridden conditions done at home until finally,...