A5045714862- Peripheral Artery Disease Management
- Venous Thromboembolism Diagnosis and Management
- Diabetic Foot Ulcer Assessment and Management
- Diagnosis and Treatment of Venous Diseases
- Vector-borne infectious diseases
- Health Systems, Economic Evaluations, Quality of Life
- Vascular Procedures and Complications
- Antioxidant Activity and Oxidative Stress
- T-cell and Retrovirus Studies
- COVID-19 and healthcare impacts
- Clinical practice guidelines implementation
- IL-33, ST2, and ILC Pathways
- Cerebrovascular and Carotid Artery Diseases
- Vasculitis and related conditions
- COVID-19 Clinical Research Studies
- Angiogenesis and VEGF in Cancer
- Lymphatic System and Diseases
- Cerebral Palsy and Movement Disorders
- Animal Disease Management and Epidemiology
- Systemic Lupus Erythematosus Research
- Insect and Pesticide Research
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Ovarian function and disorders
- Cell Adhesion Molecules Research
- Atherosclerosis and Cardiovascular Diseases
Mashhad University of Medical Sciences
2014-2024
Luigi Sacco Hospital
2019-2022
European Centre for Training and Research in Earthquake Engineering
2018-2022
Institute of Immunology
2020
Islamic Azad University, Mashhad
2020
European Institute of Oncology
2017
Gonabad University of Medical Sciences
2014
Emam Reza Hospital
2009
Imam Reza Hospital
2007
Scripps Research Institute
1993
Programmed cell death (PCD) or apoptosis is a naturally occurring suicide pathway induced in variety of types. In many cases, PCD by the withdrawal specific hormones growth factors that function as survival factors. this study, we have investigated potential role extracellular matrix (ECM) factor. Our results indicate absence any ECM interactions, human endothelial cells rapidly undergo PCD, determined morphology, nuclei fragmentation, DNA degradation, protein cross-linking, and expression...
In people with obesity, diabetes, and hypertension, lipid glucose metabolism oxidative stress generation interact. This condition, known as a “metabolic syndrome” (MetS), presents global challenge appears to be the underlying mechanism for development of cardiovascular diseases (CVDs). review is designed based on evidence indicating pathogenic mechanisms MetS. detail, we will look at induction in MetS, effects elevated levels condition’s pathophysiology, matters related endothelial function....
A 50-kDa integrin-associated protein (IAP), identified by its role in activation of neutrophils extracellular matrix proteins, has recently been found to have a primary sequence that predicts five transmembrane domains, raising the possibility participates ion transport. In endothelial cells, proteins and anti-integrin antibodies shown trigger an influx [Ca2+]i via voltage-independent membrane channels. We now show monoclonal IAP block neutrophil completely inhibited fibronectin-stimulated...
Abstract Background One year after the declaration of coronavirus disease 2019 (COVID-19) pandemic by World Health Organization (WHO) and despite implementation mandatory physical barriers social distancing, humanity remains challenged a long-lasting devastating public health crisis. Management Non-pharmacological interventions (NPIs) are efficient mitigation strategies. The success these NPIs is dependent on approval commitment population. launch mass vaccination program in many countries...
(1) Background: Thromboangiitis obliterans or Winiwarter-Buerger disease (WBD), is an inflammatory, thrombotic occlusive, peripheral vascular disease, usually occurring in young smokers. The pathophysiological mechanisms underlying the are not clearly understood. aim of this study to investigate imbalance between oxidants and antioxidants these patients. (2) Patients Methods: In cross-sectional study, 22 male patients with WBD 20 healthy smoking habit matched control group were included. To...
Nowadays, Buerger's disease (BD) is more common in the developing countries of Asia. Although its prevalence going to decrease developed countries, decline rate not parallel with that for smoking these countries. Since number BD patients reported MVasRc increasing annually and pathogenesis unknown, aim study was investigate habits socioeconomic status corresponding Shionoya's criteria.Poverty line key factor economic condition. Hygiene, education, professional occupation, long-term...
► cardiovascular disease peripheral artery deep vein thrombosis antithrombotic antiplatelets anticoagulants low-molecular-
Even today thromboangiitis obliterans has disease features that remain misunderstood or underappreciated. The epidemiology, etiology and pathophysiology of the are still unclear. Biomarkers activity markers lacking, thus clinical assessment is difficult. We struggling to establish unique diagnostic, staging treatment criteria. This an academic-collaborative effort describe pathophysiology, manifestations, diagnostic approach, challenges management patients with TAO. A systematic search for...
Buerger's disease (BD) remains a debilitating condition and early diagnosis is paramount for its effective management. Despite many published diagnostic criteria BD, selective have been utilized in different vascular centers to manage patients with BD worldwide. A recent international Delphi Consensus Study on the of showed that none these universally accepted as gold standard. Apart from presence smoking, distinct differences between them, rendering direct comparison patient outcomes...
The aim of this study was first to describe the natural history Buerger's disease (BD) and then discuss a clinical approach based on multivariate analysis. One hundred eight patients who corresponded with Shionoya's criteria were selected from 2000 2007 for study. Major amputation considered ultimate adverse event. Survival analyses performed by Kaplan–Meier curves. Independent variables including gender, duration smoking, number cigarettes smoked per day, minor events type treatments,...
The possible role of infectious pathogens in the development thromboangiitis obliterans (TAO) was considered soon after disease first described. However, it is not yet known whether induce thrombotic vasculitis or if they cause a type autoimmune disease. To investigate TAO relapses are more likely due to reinfection flare, serum levels toll-like receptor (sTLR) 4, sTLR2, C-reactive protein (CRP), and neopterin were evaluated patients during both acute quiescent phases as well gender-, age-,...