A5056002916- Atrial Fibrillation Management and Outcomes
- Cardiac pacing and defibrillation studies
- Infective Endocarditis Diagnosis and Management
- Myeloproliferative Neoplasms: Diagnosis and Treatment
- Acute Myeloid Leukemia Research
- Sexual function and dysfunction studies
- Cancer Treatment and Pharmacology
- Radiopharmaceutical Chemistry and Applications
- Venous Thromboembolism Diagnosis and Management
- Inflammatory mediators and NSAID effects
- Colorectal Cancer Treatments and Studies
- Viral Infections and Immunology Research
- Cardiac Valve Diseases and Treatments
- Cardiac Arrhythmias and Treatments
- Cardiovascular and Diving-Related Complications
- Renal and Vascular Pathologies
- Chemical Synthesis and Analysis
- Global Healthcare and Medical Tourism
- Telemedicine and Telehealth Implementation
- Mechanical Circulatory Support Devices
- Cancer-related molecular mechanisms research
- Colorectal Cancer Screening and Detection
- Celiac Disease Research and Management
- SARS-CoV-2 and COVID-19 Research
- Synthesis of β-Lactam Compounds
Université de Tours
2024
Stony Brook University
2022-2024
Centre Hospitalier Universitaire de Tours
2024
Stony Brook University Hospital
2022-2023
Miami VA Healthcare System
2020
Jacobs (United States)
2020
Aalto University
2020
Jackson Memorial Hospital
2017
University of Miami Hospital
2017
Thomas Jefferson University
2005-2016
The RE-LY trial (Randomized Evaluation of Long-Term Anticoagulant Therapy) compared dabigatran 150 and 110 mg twice daily with warfarin in 18 113 patients atrial fibrillation. Those prosthetic heart valves, significant mitral stenosis, valvular disease (VHD) requiring intervention were excluded. Others VHD included.This is a post hoc analysis the trial.There 3950 any VHD: 3101 had regurgitation, 1179 tricuspid 817 aortic 471 193 mild stenosis. At baseline, more failure, coronary disease,...
While efficient graph-based representations have been developed for modeling combinations of low-level network attacks, relatively little attention has paid to effective techniques visualizing such attack graphs. This paper describes a number new graph visualization techniques, each having certain desirable properties and offering different perspectives solving kinds problems. Moreover, the we describe can be applied not only separately, but also combined into coordinated views. We apply...
14551 Introduction: Epidermal growth factor receptor (EGFr) expression in CRC is associated with metastatic potential and poor prognosis. Panitumumab, a fully human monoclonal antibody against EGFr, was approved for the treatment of patients refractory mCRC. The main side effects panitumumab include dermatological manifestations that have been termed “rash”. However, classification has not clearly described. Methods: We summarized 19 from 3 clinical studies investigating safety efficacy...
Abstract Introduction Atrioventricular node ablation (AVNA) with permanent pacing is an effective treatment of symptomatic atrial fibrillation (AF). Permanent right ventricular associated cardiac dyssynchrony, which can worsen heart failure (HF) symptoms. Left bundle branch area (LBBAP) a recent technique, more physiologic and less dyssynchrony. Purpose To evaluate feasibility, safety outcomes at 6 months AVNA LBBAP in patients AF. Methods In this retrospective monocentric study, we included...
You have accessJournal of UrologyCME1 Apr 2023PD11-10 PHOSPHODIESTERASE-5 INHIBITOR USE AND PROGRESSION TO HEART FAILURE IN MEN WITH CORONARY ARTERY DISEASE ERECTILE DYSFUNCTION Albert Ha, George Wayne, Mark Jacobs, Andreas Kalogeropoulos, and Joseph Alukal HaAlbert Ha More articles by this author , WayneGeorge Wayne JacobsMark Jacobs KalogeropoulosAndreas Kalogeropoulos AlukalJoseph View All Author Informationhttps://doi.org/10.1097/JU.0000000000003251.10AboutPDF ToolsAdd to...
14586 Background: There are 2 monoclonal antibodies (mAbs) targeting the epidermal growth factor receptor (EGFR) available for treatment of advanced metastatic colorectal cancer- panitumumab, a fully human IgG2 kappa mAb and cetuximab, chimeric IgG1 mAb. The ability to administer one agent after prior with other is unknown further, not trivial given possibility cross-reactivity. In our institution, we evaluated an exploratory schedule. Methods: We report status 8 colon cancer pts treated...
Background: Acute decompensated heart failure (ADHF) is a primary reason for hospital admission and readmission in the elderly. Prior studies have demonstrated that sonographic pulmonary B-lines large inferior vena cava (IVC) diameter with reduced collapsibility may accurately predict ADHF readmission. Ultrasound readily available bedside tool can be used to assess patient’s volume status, which difficult under certain clinical conditions. The purpose of this project determine if...
Background: Disparities in treatment and outcomes of infective endocarditis (IE) between people who use drugs (PWUD) non-PWUD have been reported, but long-term data on cardiovascular cerebrovascular are limited. We aim to compare 5-year rates mortality, events after IE PWUD non-PWUD. Methods: Using from the TriNetX Research Network, we examined cumulative incidence myocardial infarction, heart failure, atrial fibrillation/flutter, ventricular tachyarrhythmias, ischemic stroke, intracranial...
Abstract Background The obesity paradox has been reported in 3 post-hoc analyses evaluating the direct oral anticoagulants (DOAC) against warfarin (W): apixaban (ARISTOTLE), rivaroxaban (ROCKET), and edoxaban (ENGAGE-AF). Purpose To evaluate a analysis of RE-LY trial, comparing dabigatran 110 mg BID (D110), 150 (D150), W by body mass index (BMI). Methods Baseline characteristics were evaluated using World Health Organization (WHO) criteria overweight obese (BMI ≥25 kg/m2) under normal weight...
Introduction: Spontaneous heparin-induced thrombocytopenia (HIT) is a rare clinical variant that develops without prior exposure to heparin. We present 40-year-old man who was diagnosed with spontaneous HIT after an acute ST-segment elevation myocardial infarction complicated by multiple stent thromboses and left ventricular (LV) thrombus. Case: A previously healthy no known history of heparin presented our emergency department infarction. Emergent coronary angiography revealed severely...
5598 Background: Substantial locoregional recurrence rates and metastatic disease shorten survival for patients (pts) with locally advanced HNC despite advances in concomitant chemotherapy RT. Cox 2 inhibitors are over-expressed show preclinical benefit when combined We explored the use of a cox inhibitor, celecoxib, combination weekly RT phase I study. Methods: Eligibility: Stage III, IV squamous cell cancer oral cavity, oropharynx, hypopharynx, larynx; PS 0,1,2; adequate hepatic,...
Abstract INTRODUCTION: Head and Neck Squamous Cell Carcinoma (HNSCC) is a disease that accounts for 90% of the 600,000 new diagnoses head neck cancers worldwide each year. CD44 purported cancer stem cell (CSC) marker, its colocalization with EGFR has been proposed to activate tyrosine kinase (TK) mitogen-activated protein (MAPK). Therapies tend have dismal cure rates. Understanding interaction between may result in improved therapies HNSCC. METHODS: To evaluate effect on EGFR, we inhibited...