- Chronic Kidney Disease and Diabetes
- Renal and related cancers
- Trace Elements in Health
- Vascular Procedures and Complications
- Diabetes and associated disorders
- Pharmacological Effects and Toxicity Studies
- Cancer, Hypoxia, and Metabolism
- Pharmacological Effects of Natural Compounds
- Cell death mechanisms and regulation
- Vascular anomalies and interventions
- Bone Metabolism and Diseases
- Mitochondrial Function and Pathology
- Central Venous Catheters and Hemodialysis
- Nutrition and Health in Aging
- Vitamin C and Antioxidants Research
- Cannabis and Cannabinoid Research
- Selenium in Biological Systems
- Dialysis and Renal Disease Management
- Parathyroid Disorders and Treatments
- Pancreatic function and diabetes
CHA Bundang Medical Center
2020-2023
CHA University
2020-2023
Severance Hospital
2020
Yonsei University
2020
Samsung Medical Center
2002
Sungkyunkwan University
2002
Abstract Background PTEN-induced kinase 1 (PINK1) is a serine/threonine-protein in mitochondria that critical for mitochondrial quality control. PINK1 triggers mitophagy, selective autophagy of mitochondria, and involved regeneration. Although increments biogenesis activity are known to be crucial during differentiation, data regarding the specific role osteogenic maturation bone remodeling limited. Methods We adopted an ovariectomy model female wildtype Pink1 −/− mice. Ovariectomized mice...
Systemic inflammation has been proposed as a relevant factor of vascular remodeling and dysfunction. We aimed to identify circulating inflammatory biomarkers that could predict future arteriovenous fistula (AVF) dysfunction in patients undergoing hemodialysis. A total 282 hemodialysis were enrolled this prospective multicenter cohort study. Plasma cytokine levels measured at the time data collection. The primary outcome was occurrence AVF stenosis and/or thrombosis requiring percutaneous...
Abstract Background/AimsPatients with chronic kidney disease (CKD) experience much more marked and earlier muscle wasting than subjects who do not have illnesses. However, a few studies that examined sarcopenia been reported in CKD patients. We investigated the prevalence of predialysis dialysis outpatients explored its relationship clinical outcomes.MethodsSarcopenia was defined as reduced strength accompanied by decreased adjusted appendicular skeletal (ASM), while those patients exhibited...