A5066202055- Alzheimer's disease research and treatments
- Mitochondrial Function and Pathology
- Connective tissue disorders research
- Medical Imaging and Analysis
- Prenatal Screening and Diagnostics
- Neurological Disorders and Treatments
- Congenital limb and hand anomalies
- Orthopedic Surgery and Rehabilitation
- Spine and Intervertebral Disc Pathology
- Traumatic Brain Injury and Neurovascular Disturbances
- Nail Diseases and Treatments
- Diet and metabolism studies
- Cutaneous Melanoma Detection and Management
- Spinal Fractures and Fixation Techniques
- Tumors and Oncological Cases
- Cleft Lip and Palate Research
- Genetic Syndromes and Imprinting
- Stress Responses and Cortisol
- Craniofacial Disorders and Treatments
- Biological Research and Disease Studies
- Cholinesterase and Neurodegenerative Diseases
Sunnybrook Research Institute
2016-2020
Sunnybrook Health Science Centre
2020
Dalhousie University
2013-2018
Izaak Walton Killam Health Centre
2017-2018
Sunnybrook Hospital
2016
Physical activity has been correlated with a reduced risk of cognitive decline, including that associated vascular dementia, mild impairment (MCI) and Alzheimer's disease (AD); recent literature suggests this may in part result from benefits to the cerebrovascular network. Using transgenic (Tg) mouse model AD, we evaluated effect running on cortical hippocampal morphology, cerebral amyloid angiopathy, plaque load, spatial memory. TgCRND8 mice present progressive pathology, advancing cortex...
Prader-Willi syndrome (PWS) patients can present with scoliosis which be treated serial cast correction (SCC) or growth friendly surgery (GFS). This study's purpose was to describe the results of SCC as well GFS for PWS early-onset (EOS).PWS were identified from 2 international multicenter EOS databases. Scoliosis, kyphosis, spine height (T1-S1), right/left hemithoracic heights/widths (RHTH, LHTH, RHTW, LHTW) measured pretreatment, postoperation, and at 2-year follow-up. Complications...
Student Award-Winning PaperMouse models of Alzheimer’s disease (AD) show both cognitive and neuromotor impairments. We measured motor ability learning male female triple transgenic (3×Tg-AD) control (B6129SF1/J) mice on the accelerating Rotarod in a cross-sectional design at 2, 6, 9, 12, 15 months age. At all ages except for 2 months, performed better had steeper curve than controls. Female showed performance males, while males females. Age did not have significant main effect performance....
Cerebrovascular integrity is fundamental for neuronal function. A robust and healthy vascular network required normal development, maintenance transmission. In the pathological context, cerebral vasculature gaining recognition as an important therapeutic target Alzheimer's disease (AD). Changes to morphology are associated with accumulation of amyloid beta (Aβ) plaques, angiopathy (CAA), which compromises cerebrovasculature induces neurotoxicity, resulting in cognitive impairment. Physical...
# 0107: Nationwide quality assessment of the Canadian Spine Outcomes Research Network (CSORN) {#article-title-2} The and is an emergent, rapidly growing national spine registry. utility a medical database dependent on
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