A5079437830- Head and Neck Surgical Oncology
- Renal cell carcinoma treatment
- Renal and related cancers
- Cutaneous Melanoma Detection and Management
- Head and Neck Cancer Studies
- Photodynamic Therapy Research Studies
- Cancer Research and Treatments
- Urinary and Genital Oncology Studies
- Ear and Head Tumors
- Bone Tumor Diagnosis and Treatments
- Cancer Diagnosis and Treatment
- Tracheal and airway disorders
- Melanoma and MAPK Pathways
- Cancer Cells and Metastasis
- 3D Printing in Biomedical Research
- Viral-associated cancers and disorders
- bioluminescence and chemiluminescence research
- Estrogen and related hormone effects
- Immunotherapy and Immune Responses
- Oral Health Pathology and Treatment
- Cancer-related gene regulation
- Metabolism, Diabetes, and Cancer
- Wnt/β-catenin signaling in development and cancer
- Cervical Cancer and HPV Research
- Oral health in cancer treatment
Sechenov University
2019-2024
Russian Railways
2024
Central Clinical Hospital
2024
Federal Medical-Biological Agency
2023
This article presents the results of intraoperative fluorescent diagnostics via endoscopic system for assessing quality photodynamic therapy (PDT) head and neck cancer. The diagnosis PDT procedures were performed on five patients with malignant neoplasms vocal cords, lateral surface tongue, trachea cancer left parotid salivary gland. Molecular form chlorin E6 (Ce6) was intravenously administered a 1.0-1.1 mg/kg concentration PDT. Fluorescent (FD) conducted before after procedures. Control...
Currently, the choice of treatment method for HNSCC is based on anatomical localization, tumor stage (T) and lymph node involvement (N) without taking into account biological heterogeneity tumors. The most important genetic alterations in are described TCGA study with delineation two large cohorts patients according to HPV (human papillomavirus) status different carcinogenesis pathways. As a result profiling squamous cell carcinomas using high-throughput transcriptomic analysis, studying...
Hereditary papillary renal carcinoma (HPRC) is a rare autosomal dominant disease characterized by the development of multiple type I cell carcinomas. This hereditary kidney cancer form caused activating mutations in MET. Descriptions patients with HPRC are scarce world literature, and no cases have been described open sources Russia. Here, we describe 28-year-old female Russian patient 7 10 primary carcinomas left right kidneys, respectively. The did not family history any known syndromes. A...
Due to the high prevalence of pre-cancerous cervical diseases and cancer, search, pathogenetic reasoning evaluation efficacy new approaches diagnosis treatment these pathologies, including those aimed at fertility preservation, are extremely relevant. Objective. To study clinical safety phototheranostics as a method severe dysplasia pre-invasive cancer. Patients methods. An open-label, retrospective-prospective, randomized, comparative, trial involving 94 reproductive-aged patients with...
Searchable abstracts of presentations at key conferences in endocrinology ISSN 1470-3947 (print) | 1479-6848 (online)
Aim of the study : to present and summarize current data on prognostic value E-cadherin β-catenin markers for head neck squamous cell carcinoma, as well substantiate potential benefit from implementing research results into clinical practice within framework a personalized approach treatment carcinoma. Material Methods . We performed literature search review in Pubmed, Scopus, Google Scholar RSCI databases regarding association level with disease prognosis, aggressiveness tumor behavior...
Background: Cutaneous melanoma is an extremely aggressive disease with unpredictable prognosis. Even among patients similar tumor parameters and extent of surgical treatment, survival may vary. The resection primary cutaneous well-established, a BRAF mutation in the unfavorable prognostic factor for patient survival. presence mainly used as marker prescribing targeted therapy. impact surgery method restoring tissue defect on stages remains unexplored. depending has also not been studied. We...
Malignant sinonasal tumors are rare and account for 1% of all neoplasms. Most these carcinomas poorly differentiated or undifferentiated tumors. Due to overlapping features, both young experienced physicians encounter difficulties in their diagnosis. We present 2 cases the tract, which belong small round blue cell tumors: neuroendocrine tumor esthesioneuroblastoma.
Introduction. Multilocular cystic renal cell neoplasm of low malignant potential (MCRCNLMP) or multilocular carcinoma (MCRCC) is classified as a distinct nosological unit. Currently, in literature there are no results studies based on large number observations. Objectives: to systemize clinical and pathomorphological characteristics MCRCNLMP. Materials methods . In the period from January 2011 December 2015 clinic N.N. Lopatkin Scientific Research Institute Urology Interventional Radiology,...
Background: The PD-L1 level is mainly used to predict the effect of drug treatment in patients with melanoma. Despite radical nature surgery these patients, rate disease progression remains high. Therefore, it important study relation between tumor and surgical options for cutaneous melanoma patient survival. Objective: To analyze primary at different levels excision closing defect. Materials methods: We data 143 stage 0IIIC who were randomized into 2 groups: main group (wide plastic...
Objective. To improve the efficacy of therapy for cervical intraepithelial neoplasia associated with human papillomavirus (HPV) infection using phototheranostics. Patients and methods. This study included 52 patients aged 22 to 53 years morphologically confirmed diagnoses varying degrees, preinvasive, microinvasive squamous cell carcinomas. All women were carriers HPV infection. Therapy control elimination assessed by results polymerase chain reaction. underwent photodynamic (PDT)...