A5065930365- Malaria Research and Control
- Mosquito-borne diseases and control
- Parasites and Host Interactions
- Parasitic Diseases Research and Treatment
- Bullying, Victimization, and Aggression
- Parasitic infections in humans and animals
- Parasitic Infections and Diagnostics
- Congenital Anomalies and Fetal Surgery
- Parasite Biology and Host Interactions
- Injury Epidemiology and Prevention
- Identification and Quantification in Food
- Genetic diversity and population structure
- Traffic and Road Safety
- Mollusks and Parasites Studies
- Toxoplasma gondii Research Studies
- Yersinia bacterium, plague, ectoparasites research
- Consumer Market Behavior and Pricing
- Computational Drug Discovery Methods
- Child Development and Digital Technology
- Viral Infections and Vectors
- Helminth infection and control
- Dengue and Mosquito Control Research
- Extracellular vesicles in disease
- COVID-19 Impact on Reproduction
- Climate Change, Adaptation, Migration
Yunnan Institute of Parasitic Diseases
2014-2025
Taiyuan University of Technology
2025
Yixing People's Hospital
2015-2024
Jiangsu University
2015-2024
Shenyang Pharmaceutical University
2008-2011
Wuxi No.2 People's Hospital
2005
Objective: Electric bike/moped-related road traffic injuries have become a burgeoning public health problem in China. The objective of this study was to identify the prevalence and potential risk factors electric among bike/moped riders southern China.Methods: A cross-sectional used interview 3,151 that occurred from July 2014 June 2015 were investigated. Data collected by face-to-face interviews analyzed between 2017.Results: investigated 15.99%. significantly associated with category bike...
Rapid and accurate detection of the zoonotic nematode Anisakis is poised to control its epidemic. The clustered regularly interspaced short palindromic repeats (CRISPR)/Cas-associated assay shows great potential in pathogenic microorganisms. one-tube method integrated CRISPR system with recombinase polymerase amplification (RPA) avoid risk aerosol pollution; however, it suffers from low sensitivity due incompatibility two systems additional manual operations. Therefore, present study,...
Implementing effective interventions remain a lot of difficulties along all border regions. The emergence artemisinin resistance Plasmodium falciparum strains in the Greater Mekong Subregion is matter great concern. China has effectively controlled cross-border transmission malaria and P. China-Myanmar border.A combined quantitative qualitative study was used to collect data, then an integrated impact evaluation conducted control during 2007-2013.The parasite prevalence rate (PPR) five...
Background: Echinococcus granulosus is a zoonotic parasitic disease caused by the larval stage of parasite Echinococcus, which has long incubation period, expensive diagnosis and treatment, duration medication, so it brings great economic burden to patients their families. Shangri‐La City one counties with high prevalence echinococcosis in Yunnan Province. The antigen‐positive rate feces there potential risk infecting people. Evaluation comprehensive prevention control intervention different...
Trichinella spiralis (T. spiralis) derived extracellular vesicles (EVs) have been proposed to play a key role in regulating the host immune responses. In this study, we provided first investigation of EVs proteomics released by T. muscle larvae (ML). ML (Ts-ML-EVs) were successfully isolated and characterized transmission electron microscopy (TEM) western blotting. Using liquid chromatograph mass spectrometer (LC-MS/MS) analysis, identified 753 proteins Ts-ML-EVs proteome annotated gene...
BACKGROUND Echinococcosis is prevalent in 9 provinces Western and Northern China. An epidemiological survey of echinococcosis 2012 2016 showed cases Yunnan Province. AIM To understand the spatial distribution characteristics for prevention control to reduce risk infection METHODS Based on China Information System Disease Control Prevention (CISDCP), reported from 36 hospitals 34 Centers were investigated epidemiologically analyzed 2021 2022. The exclusion criteria included suspected cases,...
Enterocytozoon bieneusi is the most common microsporidian species in humans and can affect over 200 animal species. Considering possible increasing risk of human E. infection due to close contact with pet dogs identification zoonotic genotypes, 589 fresh fecal specimens were collected from Yunnan Province, China determine occurrence , characterize dog-derived isolates, assess their potential at genotype level. was identified genotyped by PCR sequencing internal transcribed spacer (ITS)...
We evaluated the epidemiological characteristics of echinococcosis, a global public health threat, in China to inform control efforts. Descriptive, statistical, cluster, spatial, and trend analyses were used evaluate epidemiology at national, provincial, county levels based on 2004-2022 nationwide surveillance data from China. Between 2004 2022, recorded 72,676 cystic echinococcosis (CE) cases, 11,465 alveolar (AE) 5703 others, with an average annual cases per million (ANpM) 3.45. Females...
Despite the elimination of domestic malaria transmission within China, border areas Yunnan Province continue to face a heightened risk imported cases due presence diverse Anopheles mosquito species and widespread burden in neighboring countries. While gut microbiota offers promising avenue for developing anti-malaria strategies, meticulous investigation various their associated Yunnan's has yet be undertaken. To address this gap, field surveys were conducted over years 2020, 2021, 2023....
We investigated changes in the susceptibility of Plasmodium falciparum to artesunate vitro using Rieckmann's microtest Yunnan Province, China, during period 1988 1999. Longitudinal surveillance studies 1988, 1992 and 1999 revealed that IC50s were 6.2, 7.2 20.7 nmol/L, respectively mean concentrations completely inhibiting schizont formation (CIMC) 37.8, 46.1 74.0 respectively. The IC50 CIMC 3.3 2 times greater than 1988. In cross-sectional tests from 1991 1993, P. isolates areas western...
Abstract Background Although the numbers of malaria cases in China have been declining recent years, outbreaks Plasmodium vivax were still being reported rural areas south Yellow River. To better understand transmission dynamics P. parasites China, extent genetic diversity populations circulating Bozhou Anhui province investigated using three polymorphic markers: merozoite surface proteins 1 and 3α ( pvmsp-1 pvmsp-3α ) circumsporozoite protein pvcsp ). Methods Forty-five clinical isolates...
Enterocytozoon bieneusi is the most common microsporidian species causing diarrhea and other intestinal disorders in humans animals. Like infectious diseases, microsporidiosis usually disproportionately affects poor populations. In China, some ethnic minority areas remain poor. Currently, no information of E. infection available The present aims were to understand occurrence genetic characterizations groups from a poverty-stricken township Yunnan Province, assess risk factors for infection.
<sec> <strong>What is already known about this topic?</strong> </sec><sec> Both alveolar echinococcosis (AE) and cystic are endemic in China, among which has a very high mortality rate. added by report?</strong> The survey results showed the prevalence scope of AE China identified high-risk groups including children, monks, herdsmen illiterate people. At same time, all cases found (more than 90% patients did not go to hospital for diagnosis treatment before survey) were promptly diagnosed...
Abstract Trichinella spiralis is recognized for its ability to regulate host immune responses via excretory/secretory (ES) products. Serine protease inhibitors (serpins) play an important role in ES product-mediated immunoregulatory effects during T. infection. In this study, the properties of a serpin derived from (Ts-serpin) were explored BALB/c mice. The results showed that naturally occurring Ts-serpin was detected stichosomes muscle larvae and adult worms. Moreover, enhancing (by...
To develop an effective malaria vector intervention method in forested international border regions within the Greater Mekong Subregion (GMS), more in-depth studies should be conducted on local Anopheles species composition and bionomic features. There is a paucity of comprehensive surveys biodiversity integrating morphological molecular identification Laos Cambodia.A total 2394 adult mosquitoes were trapped Cambodia-Laos region. We first performed subsequently using 412 recombinant...
There is an urgent need for the development of new, improved vaccine adjuvants against T. spiralis infection. Polysaccharides are effective, safe, and biodegradable as adjuvant. In our study, we first observed protective efficacy lentinan adjuvant helminth Recombinant Serpin (rTs-Serpin) immunoscreened from a cDNA library spiralis, vaccine, protect host Trichinella The reduction rate burden rTs-Serpin+lentinan-immunized mice was significantly increased compared with rTs-Serpin+FCA -immunized...
Abstract Trichinella spiralis ( T. ) is a zoonotic parasitic nematode with unique life cycle, as all developmental stages are contained within single host. Excretory-secretory (ES) proteins the main targets of interactions between and host at different development essential for parasite survival. However, ES protein profiles have not been characterized. The proteomes from stages, namely, muscle larvae (ML), intestinal infective (IIL), preadult (PA) 6 h, PA 30 adult (Ad) 3 days post-infection...
Background/Objectives: Cyberbullying is an increasingly serious issue that negatively impacts the mental and physical health of adolescents. This study aims to report prevalence rates adolescent cyberbullying–victimization its associated related factors, providing a scientific basis for targeted efforts protect well-being adolescents; Methods: From March May 2019, there were 13 high schools 33 middle in Yixing, with student ratio 2:1 between school. Using random cluster sampling method, we...
Objective: Driving anger is a common emotion while driving and has been associated with traffic crashes. This study aimed to investigate situations that increase among Chinese drivers.Methods: A cross-sectional was conducted 3,101 drivers in southern China. The translated version of the 33-item Anger Scale (DAS) used measure anger. Data were collected by face-to-face interviews between June 2016 September 2016.Results: Confirmatory factor analysis showed fit original 6-factor model...