A5017307704- Surfactants and Colloidal Systems
- Pickering emulsions and particle stabilization
- Analytical Chemistry and Chromatography
- Mass Spectrometry Techniques and Applications
- Isotope Analysis in Ecology
- Metabolomics and Mass Spectrometry Studies
- Lipid Membrane Structure and Behavior
- Origins and Evolution of Life
- Innovative Microfluidic and Catalytic Techniques Innovation
- Enzyme Structure and Function
- Various Chemistry Research Topics
- Nanoparticle-Based Drug Delivery
- Phase Equilibria and Thermodynamics
- Chemistry and Chemical Engineering
- Supramolecular Chemistry and Complexes
- Covalent Organic Framework Applications
- Advanced Polymer Synthesis and Characterization
- Microbial Metabolic Engineering and Bioproduction
Georgia Institute of Technology
2018-2021
AID Atlanta
2018-2020
James Madison University
2015-2017
Carrier (United States)
2015-2017
Oligosaccharides serve many roles in extant life and may have had a significant role prebiotic chemistry on the early Earth. In both these contexts, structural isomeric diversity among carbohydrates presents analytical challenges necessitating improved separations. Here, we showcase chemical derivatization approach, where 3-carboxy-5-nitrophenylboronic acid (3C5NBA) is used to label vicinal hydroxyl groups, amplifying difference between isomers. We explore applicability of state-of-the-art...
Identifying small sugar isomers can be challenging by ion mobility-mass spectrometry (IM-MS) alone due to their collision cross section differences. Herein, we report IM-MS results for multi-site, covalent carbohydrate derivatization with 3-carboxy-5-nitrophenylboronic acid (3C5NBA). Following reaction in aqueous solutions at room temperature, 3C5NBA reacts each mono- or disaccharide molecule yield products that have a distinguishable mobility signature. The was rapid and resulted the...
An increased focus on characterizing the structural heterogeneity of carbohydrates has been driven by their many significant roles in extant life and potential chemical evolution origin life. In this work, multiplexed drift tube ion mobility-Orbitrap mass spectrometry methods were developed to analyze mixtures disaccharides modified with noncovalent shift reagents. Since traditional coupling atmospheric pressure mobility cells Orbitrap analyzers suffers from low duty cycles (<0.1%), a...
Traveling wave and drift tube ion mobility were utilized to separate isomeric disaccharides. Organic acid shift reagents necessary increase the resolution of these separations for mixture analysis.
The unique surface properties of amphiphilic molecules have made them widely used in applications where foaming, emulsifying or coating processes are needed. Novel surfactant architectures with multi-cephalic and multi-tailed reportedly enhanced their anti-bacterial activity connection tail length the nature head group, but ability to produce stabilize foam is mostly unknown. Here we report on experiments tris-cationic, triple-headed, double- single-tailed amphiphiles foamability stability...