A5065190877- Leptospirosis research and findings
- Peroxisome Proliferator-Activated Receptors
- Veterinary medicine and infectious diseases
- Adipose Tissue and Metabolism
- Enzyme-mediated dye degradation
- Viral Infections and Vectors
- Nuclear Receptors and Signaling
- Pharmacological Effects and Toxicity Studies
- Bioactive Compounds and Antitumor Agents
- Medicinal Plants and Neuroprotection
- Click Chemistry and Applications
- Veterinary Medicine and Surgery
- Pregnancy and preeclampsia studies
- Metabolism, Diabetes, and Cancer
- Retinoids in leukemia and cellular processes
- Microbial Metabolism and Applications
- Biochemical and Molecular Research
- X-ray Diffraction in Crystallography
- Reproductive tract infections research
- Monoclonal and Polyclonal Antibodies Research
- HIV/AIDS drug development and treatment
- Immune Response and Inflammation
- Reproductive Physiology in Livestock
- NF-κB Signaling Pathways
- Maternal and fetal healthcare
Instituto Butantan
2018-2022
Instituto Federal da Bahia
2022
Universidade de São Paulo
1995-2021
Universidade Federal de Alagoas
2013-2019
Universidade Federal de São Carlos
2014
Nobel Foundation
2014
Medicina
2014
Santa Casa de Misericórdia de São Carlos
2013
Group B streptococcus (GBS) is the main bacteria that infects pregnant women and can cause abortion chorioamnionitis. The impact of GBS effects on human trophoblast cells remains largely elusive, actions toward anti-inflammatory strategies in pregnancy are needed. A potent molecule, uvaol a triterpene from olive oil its functions trophoblasts unknown. We aimed to analyze biomechanical functional inactivated cells, with addition test potential benefits.HTR-8/SVneo were treated incubated GBS....
Plant peroxidases are presently used extensively in a wide range of biotechnological applications owing to their high environmental and thermal stability. As part efforts towards the discovery appealing new enzymes, peroxidase from leaves palm tree Chamaerops excelsa (CEP) was extracted, purified crystallized its native form. An X-ray diffraction data set collected at synchrotron source analysis showed that CEP crystals belonged orthorhombic space group P 2 1 , with unit-cell parameters =...
Biopharmaceutical production is currently a multibillion-dollar industry with high growth perspectives. The research and development of biologically sourced pharmaceuticals are extremely important reality in our current healthcare system. Interferon alpha consensus (cIFN) non-natural synthetic antiviral molecule that comprises all the most prevalent amino acids IFN-α into one protein sequence. For clinical use, cIFN produced E. coli form inclusion bodies. Here, we describe use two solubility...
The genus Streptomyces is characterized by the production of a wide variety secondary metabolites with remarkable biological activities and broad antibiotic capabilities. presence an unprecedented number genes encoding hydrolytic enzymes industrial appeal such as epoxide hydrolases (EHs) reveals its resourceful microscopic machinery. whole-genome sequence sp. CBMAI 2042, endophytic actinobacterium isolated from Citrus sinensis branches, was explored genome mining, putative α/β-epoxide...
Abstract Diabetes is an important chronic disease affecting about 10% of the adult population in US and over 420 million people worldwide, resulting 1.6 deaths every year, according to World Health Organization. The most common type disease, 2 diabetes, can be pharmacologically managed using oral hypoglycemic agents or thiazolidinediones (TZDs), such as pioglitazone, which act by activating Peroxisome Proliferated-Activated Receptor γ. Despite their beneficial effects diabetes treatment,...