Bo Cao

ORCID: 0000-0003-4621-9924
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About
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Research Areas
  • Cancer-related molecular mechanisms research
  • Simulation and Modeling Applications
  • Osteoarthritis Treatment and Mechanisms
  • Military Defense Systems Analysis
  • Advanced Decision-Making Techniques
  • Optical Imaging and Spectroscopy Techniques
  • Circular RNAs in diseases
  • Mesenchymal stem cell research
  • Advanced Fluorescence Microscopy Techniques
  • Thyroid Cancer Diagnosis and Treatment
  • Cancer, Hypoxia, and Metabolism
  • Adipose Tissue and Metabolism
  • Natural product bioactivities and synthesis
  • Protease and Inhibitor Mechanisms
  • Plant Toxicity and Pharmacological Properties
  • Intermetallics and Advanced Alloy Properties
  • Nanoplatforms for cancer theranostics
  • Sesquiterpenes and Asteraceae Studies
  • Bone Tissue Engineering Materials
  • RNA modifications and cancer
  • Metal Alloys Wear and Properties
  • Software Engineering and Design Patterns
  • Cardiac, Anesthesia and Surgical Outcomes
  • Photoacoustic and Ultrasonic Imaging
  • S100 Proteins and Annexins

Weifang Medical University
2015-2024

First Affiliated Hospital of Xinjiang Medical University
2017-2024

Orthopedic Center
2024

Xinjiang Medical University
2017-2024

Chinese PLA General Hospital
2023

Accumulating data have implicated that long noncoding RNA (lncRNA) plays an important role in osteoarthritis (OA), which may function as a competitive endogenous (ceRNA) of microRNAs (miRNAs). lncRNA IGHC γ 1 has been demonstrated to regulate inflammation and autoimmunity. Nonetheless, the altering effect OA remains unclear. This study is aimed at investigating mechanism OA. CCK-8, EdU, transwell assays were used estimate macrophage proliferation migration. Fluorescence situ hybridization...

10.1155/2020/9743037 article EN cc-by Mediators of Inflammation 2020-01-17

Digestive tract cancer is one of the most common types cancers globally, with ~4.8 million new cases and 3.4 cancer‑associated deaths in 2018, accounting for 26% incidence 35% cancer‑related worldwide. S100 protein family involved regulating cell proliferation, angiogenesis, epithelial‑mesenchymal transition (EMT), metastasis, metabolism immune microenvironment homeostasis. The critical role digestive involves complicated mechanisms, such as stemness remodeling, anaerobic glycolysis...

10.3892/ijo.2024.5647 article EN International Journal of Oncology 2024-04-24

The main limitation of tissue engineering lies in the inability to stimulate osteogenesis, angiogenesis stem cells and broad-spectrum antimicrobial activity. However, development multifunctional bioactive materials with these capabilities remains a great challenge. In this study, we prepared mesoporous silica nanoparticles encapsulated silver nanocrystals (AG-MSN) uniform sphere size mesopores. Platelet-derived growth factor BB (PDGF-BB) was effectively loaded AG-MSN mesopores (P-AG-MSN)....

10.1371/journal.pone.0172499 article EN cc-by PLoS ONE 2017-03-30

Edaravone is a newly developed clinical medicine for the treatment of acute cerebral infarction. Reduced blood supply to bones (hypoxia) has been involved in pathological development osteoporosis. In this study, we investigated effect and its latent mechanism on hypoxia-induced cell toxicity MC3T3-E1 cells. Cell viability was determined by 3-(4,5-dimethyl-thiazol-2yl)-2,5-diphenyl tetrazolium bromide (MTT) assay. Intracellular reactive oxygen species (ROS) nitric oxide (NO) were fluorescence...

10.1002/iub.1436 article EN IUBMB Life 2015-11-23

<title>Abstract</title> <bold>Background</bold> Although the Proximal Femoral Nail Antirotation (PFNA) is currently considered to be one of preferred treatment methods for intertrochanteric fractures. external fixation method can provide similar clinical results. The also more minimally invasive such as Orthofix Pertrochanteric Fixator (OPF). We expect that use (OPF) will reduce incidence complications. have applied a trial compare effectiveness and Complications two surgical in elderly...

10.21203/rs.3.rs-2581678/v1 preprint EN cc-by Research Square (Research Square) 2024-12-12

Combat simulation has become the important means to training and design of combat simulation. Within progress researching developing system, how building up environment that comes close realistic field, on departure whole describing activity unit in This paper put forward concept CABC (Combat Agent Based Command) according instruction mechanism, it combined autonomy restriction into fact, can react with agents proactively or passively. is autonomous, proactive, social intelligent.

10.4028/www.scientific.net/amm.182-183.1719 article EN Applied Mechanics and Materials 2012-06-01

Rational theory of finite virtual soldiers on the concept bounded rationality, rationality analysis added features soldiers, given limited based overall framework using model to make real with similar perception, decision making and exercise capacity, for subsequent implementation modules laid foundation framework.

10.4028/www.scientific.net/amm.198-199.746 article EN Applied Mechanics and Materials 2012-09-01

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at glance that was extracted from about 200 leading journals. To access of an article which published elsewhere, please select “Full Text” option. The original trackable via the “References”

10.1002/chin.200802178 article EN ChemInform 2007-12-20

10.2991/icseee-18.2019.114 article EN cc-by-nc Proceedings of the 2018 7th International Conference on Sustainable Energy and Environment Engineering (ICSEEE 2018) 2019-01-01
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