A5058593693- COVID-19 Clinical Research Studies
- Long-Term Effects of COVID-19
- SARS-CoV-2 and COVID-19 Research
- COVID-19 and Mental Health
- Respiratory viral infections research
- Antibiotic Use and Resistance
- Antibiotic Resistance in Bacteria
- Trace Elements in Health
- Antibiotics Pharmacokinetics and Efficacy
- Vitamin C and Antioxidants Research
- Pneumonia and Respiratory Infections
- Sepsis Diagnosis and Treatment
- Pneumocystis jirovecii pneumonia detection and treatment
- Diabetes Treatment and Management
- Herpesvirus Infections and Treatments
- COVID-19 and healthcare impacts
- Bariatric Surgery and Outcomes
- Bacterial Identification and Susceptibility Testing
- Health Systems, Economic Evaluations, Quality of Life
- Thermal Regulation in Medicine
- Hepatitis C virus research
- Nosocomial Infections in ICU
- Dermatological and COVID-19 studies
- Cardiovascular and exercise physiology
- Multiple Sclerosis Research Studies
Chi Mei Medical Center
2021-2025
Chang Gung Memorial Hospital
2022-2024
Fooyin University
2023-2024
Industrial Technology Research Institute
2024
Chang Gung University
2022-2024
National Sun Yat-sen University
2021-2023
SK Group (Japan)
2023
ABSTRACT Background and Aims Glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) sodium‐glucose cotransporter‐2 inhibitors (SGLT2is) have demonstrated long‐term liver benefits in patients with metabolic dysfunction‐associated steatotic disease (MASLD) type 2 diabetes (T2D). However, no direct comparison between these therapies has been conducted. This study aimed to compare major adverse outcomes (MALOs) GLP‐1 RAs SGLT2is MASLD T2D. Methods Using the TriNetX Research Network, a...
Abstract The long‐term risk of herpes zoster (HZ) after recovery from a SARS‐CoV‐2 infection is unclear. This retrospective cohort study assessed the HZ in patients following COVID‐19 diagnosis. retrospective, propensity score‐matched was based on multi‐institutional research network TriNetX. incident with compared that those not infected during 1‐year follow‐up period. Hazard ratios (HRs) and 95% confidence intervals (CIs) its subtypes were calculated. identified 1 221 343 without diagnoses...
The effect of nirmatrelvir plus ritonavir (NMV-r) on post-acute COVID-19 sequelae beyond 3 months SARS-CoV-2 infection remains unknown. This retrospective cohort study utilized data from the TriNetX Research Network. We identified nonhospitalized adult patients with receiving a diagnosis between January 1 and July 31, 2022. Propensity score matching (PSM) was used to create two matched cohorts: NMV-r non-NMV-r groups, respectively. measured primary outcomes using composite all-cause...
Objective This study aimed to investigate the association between zinc deficiency (ZD) and risks of all-cause mortality, major adverse cardiovascular events (MACEs), kidney (MAKEs), hospitalization in diabetic patients.
Abstract The aim of this study was to investigate the clinical efficacy a combination nirmatrelvir and ritonavir (NMV‐r) for treating COVID‐19 in patients with diabetes mellitus (DM). This retrospective cohort used TriNetX research network identify adult diabetic between January 1, 2020, December 31, 2022. Propensity score matching match who received NMV‐r (NMV‐r group) those did not receive (control group). primary outcome all‐cause hospitalization or death during 30‐day follow‐up period....
Abstract Several randomized controlled trials and real‐world cohort studies have demonstrated the efficacies of nirmatrelvir plus ritonavir (NMV‐r) molnupiravir (MOV) in at‐risk patients with COVID‐19; however, effectiveness antisevere acute respiratory syndrome‐coronavirus 2 treatments on older (≥65 years) remains unclear. This retrospective study aimed to assess clinical oral antiviral agents, MOV NMV‐r, infected severe 2. Nonhospitalized COVID‐19 between January 1, 2022, December 31, were...
Abstract Although a novel oral antiviral agent can improve short‐term COVID‐19 outcomes, its effects on the long‐term namely risk of major adverse cardiovascular events (MACEs), remains unknown. This retrospective cohort study used TriNetX research network to identify nonhospitalized adult patients with between March 1, 2020, and January 2022. A propensity score matching method was form two matched cohorts without receiving nirmatrelvir–ritonavir (NMV‐r) or molnupiravir. The primary outcome...
Abstract This study assessed the clinical efficacy of nirmatrelvir plus ritonavir (NMV‐r) in treating patients with coronavirus disease‐2019 (COVID‐19) and substance use disorders (SUDs). included two cohorts: first examined SUDs, without a prescription for NMV‐r, while second compared prescribed diagnosis SUDs. SUDs were defined using ICD‐10 codes, related to including alcohol, cannabis, cocaine, opioid, tobacco (TUD). Patients underlying COVID‐19 identified TriNetX network. We used 1:1...
Abstract The retrospective cohort was conducted to assess the effect of nirmatrelvir‐ritonavir (NMV‐r) on long‐term risk neuropsychiatric sequela following COVID‐19. TriNetX research network used identify nonhospitalized adult patients who tested positive for severe acute respiratory syndrome coronavirus 2 infection or were diagnosed with COVID‐19 between March 1, 2020 and July 2022. Further propensity score matching method create two matched cohorts without receiving NMV‐r. primary outcome...
This study investigated the clinical effectiveness of nirmatrelvir plus ritonavir (NMV-r) on short-term outcome and risk postacute sequelae severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection (PASC) among pediatric patients with disease 2019 (COVID-19). retrospective cohort used TriNetX research network to identify between 12 18 years COVID-19 January 1, 2022 August 31, 2023. The propensity score matching (PSM) method was match receiving NMV-r (NMV-r group) those who did...
Background Rezum water vapor therapy and UroLift are among the minimally invasive surgical therapies (MISTs) gaining popularity in treatment of benign prostatic hyperplasia (BPH). This study aims to evaluate compare reintervention rates, a measure durability, for as MISTs BPH. Methods We conducted retrospective cohort using data from TriNetX Global Collaborative Network, large database electronic health records January 2014 June 2024. Current Procedural Terminology (CPT) International...
Abstract Aims This real‐world study compared clinical outcomes between tirzepatide treatment and bariatric metabolic surgery (BMS) in adults with obesity. Methods retrospective cohort used the TriNetX network to identify a body mass index (BMI) ≥ 30 kg/m 2 . Patients initiating were those undergoing BMS. The primary outcome was all‐cause mortality, while secondary included major adverse cardiovascular events (MACEs) kidney (MAKEs). Hazard ratios (HRs) 95% confidence intervals (CIs)...
Background Given that atrial fibrillation (AF) s associated with a high risk of psychiatric disorders, understanding the potential benefits catheter ablation is clinically significant. This study was conducted to examine whether can prevent disorders in patients AF. Methods A retrospective cohort over two years using data from TriNetX electronic health record network. The included adults diagnosed AF and treated either antiarrhythmic or rate-control medications. Participants were divided...
The comparability of outcomes for non-hospitalized COVID-19 outpatients during the Omicron wave to with influenza remains uncertain. This study aims compare and seasonal fall-winter 2022–2023. is a retrospective cohort using TriNetX, collaborative clinical research platform. Non-hospitalized between 01 October 2022 31 January 2023 were selected from TriNetX. Propensity score matching (PSM) was used patients receiving corresponding outpatient antiviral treatments. Hazard ratios (HRs) 95%...