A5056599207- COVID-19 Clinical Research Studies
- Long-Term Effects of COVID-19
- Vitamin C and Antioxidants Research
- Trace Elements in Health
- Respiratory viral infections research
- RNA and protein synthesis mechanisms
- Machine Learning in Bioinformatics
- SARS-CoV-2 and COVID-19 Research
- Pneumonia and Respiratory Infections
- scientometrics and bibliometrics research
- MicroRNA in disease regulation
- Immune cells in cancer
- Thermal Regulation in Medicine
- Nutrition and Health in Aging
- Vitamin D Research Studies
- Magnesium in Health and Disease
- Frailty in Older Adults
- Meta-analysis and systematic reviews
- Immunotherapy and Immune Responses
- Dietary Effects on Health
- Potassium and Related Disorders
- Hydrogen's biological and therapeutic effects
- Pharmacological Effects and Toxicity Studies
- Ferroptosis and cancer prognosis
- Anesthesia and Pain Management
Chi Mei Medical Center
2020-2025
Chang Jung Christian University
2020-2025
Chia Nan University of Pharmacy and Science
2023-2025
Chung Hwa University of Medical Technology
2022-2025
Guangzhou Medical University
2012-2024
State Key Laboratory of Respiratory Disease
2022
Zhujiang Hospital
2021
Southern Medical University
2021
Chung Shan Medical University
2020
University of Hong Kong
2019
Effective clinical communication skills are essential for dietitians as it impacts patient outcomes and satisfaction across diverse public healthcare settings. Despite its importance a core competency, many dietetics programs, including those in Taiwan, need to provide sufficient training this area. This study aimed develop assess scenario-based simulation course improve dietetic students. A non-randomized control group pretest–posttest design was used. The intervention consisted of 12-week...
Objective This study aimed to investigate the association between zinc deficiency (ZD) and risks of all-cause mortality, major adverse cardiovascular events (MACEs), kidney (MAKEs), hospitalization in diabetic patients.
The role of miR-26a in cancer cells seemed controversial previous studies. Until now, the gastric remains undefined. In this study, we found that was strongly downregulated (GC) tissues and cell lines, its expression levels were associated with lymph node metastasis clinical stage, as well overall survival replase-free GC. We also ectopic inhibited GC proliferation vitro vivo. further identified a novel mechanism to suppress growth metastasis. FGF9 proved be direct target miR-26a, using...
Abstract The aim of this study was to investigate the clinical efficacy a combination nirmatrelvir and ritonavir (NMV‐r) for treating COVID‐19 in patients with diabetes mellitus (DM). This retrospective cohort used TriNetX research network identify adult diabetic between January 1, 2020, December 31, 2022. Propensity score matching match who received NMV‐r (NMV‐r group) those did not receive (control group). primary outcome all‐cause hospitalization or death during 30‐day follow‐up period....
We have found that hydrogen (dihydrogen [H2]) decreases plasma low-density lipoprotein (LDL) cholesterol levels and improves high-density (HDL) function in patients with potential metabolic syndrome a before-after self-controlled study.The purpose of this study was to further characterize the effects H2-rich water (0.9 L/day) on content, composition, biological activities lipoproteins hypercholesterolemia their underlying mechanisms double-blinded, randomized, placebo-controlled trial.This...
Abstract The gray level run length matrix (GLRLM) whose entries are statistics recording distribution and relationship of images pixels is a widely used method for extracting statistical features medical images, e.g., magnetic resonance (MR) images. Recently these usually employed in some artificial neural networks to identify distinguish texture patterns. But GLRLM construction extraction tedious computationally intensive while the too big with high resolution, or there many small...
This study investigated the clinical effectiveness of nirmatrelvir plus ritonavir (NMV-r) on short-term outcome and risk postacute sequelae severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection (PASC) among pediatric patients with disease 2019 (COVID-19). retrospective cohort used TriNetX research network to identify between 12 18 years COVID-19 January 1, 2022 August 31, 2023. The propensity score matching (PSM) method was match receiving NMV-r (NMV-r group) those who did...
(1) Background: Persistent hyperglycemia in diabetes mellitus (DM) increases the risk of death and causes cardiovascular disease (CVD), resulting significant social economic costs. This study used a machine learning (ML) technique to build prediction models with factors lifestyle, medication compliance, self-control eating habits then implemented predictive system based on best model forecast whether blood glucose can be well-controlled within 1 year diabetic patients attending DM...
Non-small-cell lung cancer (NSCLC) is the most prevalent worldwide. Tumor microenvironment (TME) plays a very important role in development. Thus, it urgent to find change of TME that contributes NSCLC carcinogenesis and progression.The bioinformatics analysis approach was applied evaluate screen differentially immune cells tissue based on The Cancer Genome Atlas (TCGA) data. Meanwhile, association with tumor stage prognosis evaluated. Then, we different expression genes between macrophages...
Objectives This study investigated the outcomes of underweight patients with COVID-19 and effectiveness antiviral agents in this population.
The Hirsch-index (h-index) is a measure of academic productivity that incorporates both the quantity and quality an author's output. However, it still affected by self-citation behaviors. This study aims to determine research output rates (SCRs) in Journal Medicine (Baltimore), establishing benchmark for bibliometrics, addition identifying significant differences between stages from 2018 2021.We searched PubMed database obtain 17,912 articles published 2021 (Baltimore). Two parts were...
Varicella zoster virus (VZV) is a highly contagious herpesvirus with potential for nosocomial transmission. However, the importance of chickenpox outbreak in China has often been ignored. With increasing immunocompromised population China, thorough review issues related to transmission and seroprevalence rate VZV among healthcare workers necessary.Retrospective case finding was conducted between January 1, 2013 December 31, 2017. Cases were identified based on clinical features compatible...
The effect of anemia on the post-acute outcome patients with severe acute respiratory syndrome coronavirus 2 infection was unclear. This study aimed to investigate potential association between nutritional deficiency (NDA) status and sequelae SARS-CoV-2 infection. retrospective cohort included disease (COVID-19) from January 1, 2022 November 30, using TriNetX research network. were grouped into NDA group comprising diagnosed control without NDA, propensity score matching (PSM) performed...
The human genome consists of 98.5% non-coding DNA sequences, and most them have no known function. However, a majority disease-associated variants lie in these regions. Therefore, it is critical to predict the function DNA. Hence, we propose NCNet, which integrates deep residual learning sequence-to-sequence networks, transcription factor (TF) binding sites, can then be used functions. In networks are enhance identification rate regulatory patterns motifs, so that network may make out...
Although immunotherapy has improved the clinical treatment of lung adenocarcinoma (LUAD), many tumors have poor responses to immunotherapy. In this study, we confirmed that high expression Cyclin-Dependent Kinase 7 (CDK7) promoted an immunosuppressive macrophage phenotype and infiltration in LUAD. Thus, developed internalizing-RGD (iRGD)-conjugated gold nanoparticle (AuNP) system which carries siCDK7 activate antitumor immune response. The iRGD-conjugated AuNP/siCDK7 exhibited good tumor...
To evaluate the analgesic effects of intravenous magnesium in patients undergoing thoracic surgery. Randomised clinical trials (RCTs) were systematically identified from MEDLINE, EMBASE, Google Scholar and Cochrane Library inception to May 1st, 2023. The primary outcome was effect on severity postoperative pain at 24 hours following surgery, while secondary outcomes included association between other time points, morphine consumption, haemodynamic changes. Meta-analysis seven RCTs published...
This study explored machine learning’s potential in predicting the nutritional status and outcomes for pneumonia patients. It focused on 4,368 patients a Taiwan medical center from Jan 2016 to Feb 2022, excluding ICU cases. The average age was 77.6 years, with 10.2% well-nourished, 76.3% at-risk, 13.5% malnourished. Machine learning models, particularly LightGBM XGBoost, showed high accuracy hospital stays, mortality rates, readmissions. These findings emphasize role of data-driven methods...
Objectives This study examined the effectiveness of nirmatrelvir plus ritonavir (NMV-r) and molnupiravir (MOV) in treating COVID-19 among chronic kidney disease (CKD) patients.
Background Previous studies have suggested that zinc deficiency (ZD) may increase the risk of short-term mortality in patients with coronavirus disease 2019 (COVID-19). However, relationship between status and post-acute COVID-19 outcomes remains unclear. This study aimed to determine association ZD long-term COVID-19. Methodology We conducted a retrospective cohort using TriNetX database, including aged 18 years or older diagnosed January 1, 2022, July 31, 2023. Patients had documented...