A5073935755- Neuroendocrine Tumor Research Advances
- Lung Cancer Research Studies
- Neuroblastoma Research and Treatments
- Lymphoma Diagnosis and Treatment
- CAR-T cell therapy research
- Immunotherapy and Immune Responses
- Medical Imaging Techniques and Applications
- Pancreatic and Hepatic Oncology Research
- Quantum Chromodynamics and Particle Interactions
- Particle physics theoretical and experimental studies
- Nuclear physics research studies
- Atomic and Subatomic Physics Research
- Monoclonal and Polyclonal Antibodies Research
- Neutrino Physics Research
- Infectious Aortic and Vascular Conditions
- Nanoparticle-Based Drug Delivery
- Radiomics and Machine Learning in Medical Imaging
- Radiation Detection and Scintillator Technologies
- CNS Lymphoma Diagnosis and Treatment
- Radiopharmaceutical Chemistry and Applications
- Nuclear Physics and Applications
- Dark Matter and Cosmic Phenomena
- Vascular Procedures and Complications
- Chronic Lymphocytic Leukemia Research
- Infective Endocarditis Diagnosis and Management
Azienda Ospedaliera Sant'Andrea
2015-2025
Sapienza University of Rome
2001-2024
CTO Andrea Alesini
2008-2022
Istituti Clinici Scientifici Maugeri
2018-2019
University of Milano-Bicocca
2018-2019
University of Milan
2018
Azienda Ospedaliera S.Giuseppe Moscati
2016
Istituto Nazionale di Fisica Nucleare
1986-2011
Istituto Nazionale di Fisica Nucleare, Sezione di Roma I
1989-2009
Policlinico Umberto I
2003
White blood cell (WBC) scintigraphy is considered the nuclear medicine imaging gold standard for diagnosing osteomyelitis in diabetic foot. Recent papers have suggested that use of (18)F-FDG PET/CT produces similar diagnostic accuracy, but clear interpretation criteria not yet been established. Our aim was to evaluate role sequential patients with a high suspicion define objective be compared WBC scintigraphy.Thirteen whom clinicians positive (7 ulcers, 6 exposed bone) were enrolled. The...
Abstract Background The role of 18F-fluorodeoxyglucose positron emission tomography (18F-FDG PET) in the diagnostic algorithm entero-pancreatic neuroendocrine neoplasms (EP NENs) is unclear because most available data derive from heterogeneous populations terms tumor biology and disease status at time examination. aim this study was to determine ability 18F-FDG PET identify patients with more aggressive among those advanced EP NENs. Subjects, Materials, Methods . Patients NENs known...
Multidisciplinary approach is widely advised for an effective care of patients with neuroendocrine neoplasia (NEN). Since data on efficacy multidisciplinary management NENs in referral centers are scanty, this study aimed at analyzing the modality presentation and clinical outcome managed by a dedicated team.In prospective observational study, we included all consecutive new visiting Sant'Andrea Hospital Rome (ENETS-Center Excellence) between January 2014 June 2018.A total 195 were...
This study was aimed at evaluating the feasibility, safety, immunologic and clinical responses in patients with follicular lymphoma treated monocyte-derived dendritic cells generated presence of IFNα GM-CSF (IFN-DC) combination low doses rituximab.Firstly, we analyzed vitro vivo properties IFN-DC against lymphoma. Thus, performed a phase I trial 8 refractory relapsed based on sequential intranodal injections low-dose rituximab unloaded report clinical, results enrolled patients.Preclinical...
Introduction: Thyroidectomy followed by radioactive iodine therapy (RAI) is the treatment of choice for differentiated thyroid carcinoma (DTC). Serum thyroglobulin (Tg) measurement has proved to be useful predicting persistent and/or recurrent disease during follow-up DTC patients. In our study, we evaluated risk recurrence in patients with papillary (PTC), who were treated thyroidectomy and RAI, measuring serum Tg at different time-points: least 40 days after surgery, euthyroidism TSH <...
The total cross section for deuteron photodisintegration has been measured in the $\ensuremath{\gamma}$-ray energy range between 15 and 75 MeV, by use of monochromatic LADON photon beam Frascati National Laboratories detection proton. results are substantial agreement with standard theory do not provide evidence contributions quark degrees freedom.
Functional imaging tests (FITs) detecting somatostatin receptor expression [i.e., scintigraphy, 68Ga-DOTA positron emission tomography/computed tomography (CT)] have a pivotal role in the diagnosis of neuroendocrine tumors (NETs), although their indication during follow-up still needs to be clarified.Investigate FITs after metastatic enteropancreatic NETs, identifying patients who might benefit from these exams.Multicenter retrospective analysis NETs.Analysis performed between January 1995...
Since the role of [18F]FDG PET/CT in low-grade gastroenteropancreatic (GEP) neuroendocrine neoplasia (NET) is not well established, this study was aimed to evaluate grade 1 (G1) GEP-NETs.This a retrospective including patients with G1 GEP-NETs who underwent PET/CT.55 were evaluated, 24 (43.6%) pancreatic NETs and 31 (56.4%) gastrointestinal NETs. At time diagnosis, 28 (51%) had metastatic disease, 50 (91%) positive by 68-Ga sstr PET/CT. Overall, 27 (49%) findings on Following PET/CT,...
Background: The ocular involvement of neuroendocrine neoplasms (NENs) is uncommon and mainly represented by metastases from gastrointestinal lung tumors. Primary orbital NENs are even less common their diagnostic therapeutic management a challenge. Methods: A systematic review the literature was conducted 1966 to September 2023 on PubMed identify articles summarize clinical–pathological features, diagnosis management. Furthermore, we presented case locally advanced retro-orbital primary...
Objective: Previous reports showed the reduction of dopamine transporter immunoreactivity in peripheral blood lymphocytes Parkinson's disease. In this work, we sought to investigate possible correlation between central and values a group 11 drug-naive patients with Methods: Densitometric measurements was accomplished as described recently, using monoclonal antidopamine antibody. Dopamine binding caudate putamen nuclei measured by means 123I-fluopane single-photon emission computed tomography...
Abstract To evaluate a radiomic strategy for predicting progression in advanced gastroenteropancreatic neuroendocrine tumor (GEP‐NET) patients treated with somatostatin analogs (SSAs). Fifty‐eight GEP‐NETs and liver metastases, baseline computerized tomography (CT) scans from June 2013 to November 2020, were studied retrospectively. Data collected included progression‐free survival (PFS), overall (OS), grading, death, Ki67 index. Patients categorized into progressive non‐progressive groups....