A5039647721- Edible Oils Quality and Analysis
- Phytochemicals and Antioxidant Activities
- Algal biology and biofuel production
- Antioxidant Activity and Oxidative Stress
- Essential Oils and Antimicrobial Activity
- Pesticide and Herbicide Environmental Studies
- Protein Hydrolysis and Bioactive Peptides
- Pharmaceutical and Antibiotic Environmental Impacts
- Natural Antidiabetic Agents Studies
- Pesticide Exposure and Toxicity
- Aquatic Ecosystems and Phytoplankton Dynamics
- Cultural Heritage Materials Analysis
- Advanced Proteomics Techniques and Applications
- Polysaccharides Composition and Applications
- Microbial bioremediation and biosurfactants
- Phytochemistry and Biological Activities
- Research in Cotton Cultivation
- Polysaccharides and Plant Cell Walls
- Agricultural pest management studies
- Genomics, phytochemicals, and oxidative stress
- Drug-Induced Hepatotoxicity and Protection
- Computational Drug Discovery Methods
- Plant and fungal interactions
- Phytase and its Applications
- Tea Polyphenols and Effects
Centre of Biotechnology of Sfax
2015-2025
University of Sfax
2015-2025
Despite various plans to rationalize antibiotic use, resistance in environmental bacteria is increasing due the accumulation of residues environment. This study aimed test ability basidiomycete fungal strains biotransform levofloxacin, a widely-used third-generation broad-spectrum fluoroquinolone, and propose enzyme targets potentially involved this biotransformation. The biotransformation process was performed using strains. Levofloxacin reached 100% after 9 days culture with Porostereum...
Carotenoids have strong antioxidant activity as well therapeutic value. Their production has been induced in algae under stressful culture conditions. However, the extreme conditions lead to Programmed Cell Death (PCD) of algae, which affects their growth and productivity. This study was performed evaluate effect salinity on physiological biochemical traits Scenedesmus sp., thermal freshwater microalgae from Northern Tunisia. It cultured different NaCl concentrations ranging 0 60 g/L....
Scorzonera undulata Vahl. roots are used for their nutraceutical and medicinal properties. In this work, GC-MS revealed that polysaccharides (P) the methanolic extract (MB) of S. contained 8 7 different components, respectively. They also potently inhibited Free DPPH radical (IC50% equals 103 ± 0.01 105 µg/ml, respectively) viability Hela cancer cell line (IC50 2.074 0.05 mg/ml 2.208 respectively). Furthermore, showed a relevant anti-inflammatory effect, as assayed by on carrageenan-induced...
The wastewater from hospitals, pharmaceutical industries and more generally human animal dejections leads to environmental releases of antibiotics that cause severe problems for all living organisms. aim this study was investigate the capacity three fungal strains biotransform fluoroquinolone levofloxacin. degradation processes were analyzed in solid liquid media. Among tested, Coriolopsis gallica strain CLBE55 (BRFM 3473) showed highest removal efficiency, with a 15% decrease antibiogram...
The present work was performed to investigate the phenolic composition of P. lentiscus L. distilled leaves (PDL) and examine its potential against certain key enzymes related skin aging. High-pressure liquid chromatography coupled mass spectrometry (HPLC-MS) various separation procedures combined with nuclear magnetic resonance (NMR) MS analysis were isolate identify compounds in ethyl acetate extract (EAE) PDL. A high amount flavonol glycoside detected EAE. Indeed, quercetin-3-O-rhamnoside...
Pesticides are widely used, resulting in continuing human exposure with potential health impacts. Some exposures related to agricultural works have been associated neurological disorders. Since the 2000s, hypothesis of role pesticides occurrence central nervous system (CNS) tumors has better documented literature. However, etiology childhood brain cancers still remains largely unknown. The major objective this work was assess pesticide as a risk factor for CNS based on questionnaires and...
Abstract BACKGROUND The three‐phase extraction process of olive oil produces highly contaminated wastewater (OMW). elimination this toxic by‐product is an important environmental issue that requires the development appropriate management solution. cultivation microalgae using OMW as growth medium was therefore studied single (the culture formed by 0% to 80% ultrafiltered mill (OMUF) or added BG11) and two‐stage strategies (microalgae were firstly cultivated in BG11 medium. In second stage,...
This study reports on the purification and characterization of a digestive α-amylase from blue crab (Portunussegnis) viscera designated Blue Crab Amylase (BCA). The enzyme was purified to homogeneity by ultrafiltration, Sephadex G-100 gel filtration Sepharose mono Q anion exchange chromatography, with final fold 424.02, specific activity 1390.8 U mg−1 27.8% recovery. BCA, showing molecular weight approximately 45 kDa, possesses desirable biotechnological features, such as optimal temperature...
High-grade gliomas represent the most common group of infiltrative primary brain tumors in adults associated with high invasiveness, agressivity, and resistance to therapy, which highlights need develop potent drugs novel mechanisms action. The aim this study is reveal changes proteome profiles under stressful conditions identify prognostic biomarkers altered apoptogenic pathways involved anticancer action human isocitrate dehydrogenase (IDH) mutant high-grade gliomas. Our protocol consists...
Hydrogen sulfide (H2S) and thiols (RSH) generated by the phosphate industry cause harmful effects on human health quality of life. The present study aims to investigate evaluate a bacterial strain CAT37 isolated from gas-washing wastewaters in terms its properties ability degrade malodorous thiols. Gas-washing wastewater samples were submitted physicochemical analyses used for isolation thiol-degrading bacteria. results gas chromatography–mass spectrometry (GC-MS) analysis revealed that was...
This study was designed to investigate the phytochemical profile and cytotoxic activities of eco-friendly extracts olive leaves from Chemlali cultivar.The Phenolic composition extracts, antioxidant activity effects against MCF-7 HepG2 cells were determined.Olive showed relevant total polyphenols contents. Oleuropein major detected phenolic compound reaching a concentration 16.9 mg/ml. The potential studied varied 23.7 46.5mM Trolox equivalents as revealed by DPPH ABTS assays. Cytotoxicity...
Pesticides are increasingly used in combinations crop protection, resulting enhanced toxicities for various organisms. Although protein adductomics is challenging, it remains a powerful bioanalytical tool to check environmental exposure and characterize xenobiotic adducts as putative toxicity biomarkers with high accuracy, facilitated by recent advances proteomic methodologies mass spectrometry high-throughput technique. The present study aims predict the potential neurotoxicity effect of...
The aim of this study was to develop an innovative sourdough using dehydrated okra (
The widespread use of pesticides, particularly in combinations, has resulted enhanced hazardous health effects. However, little is known about their molecular mechanism interactions. aim this study was to assess the neurotoxicity effect pesticides mixtures by adopting a 3D vitro developed neurospheroid model, followed treatment increased concentrations for 24 h and analysis shotgun proteomic-based approach with high-resolution tandem mass spectrometry. Three proteins, namely,...