A5061523191- Prostate Cancer Diagnosis and Treatment
- Prostate Cancer Treatment and Research
- Cancer Diagnosis and Treatment
- Nutrition, Health and Food Behavior
- Lung Cancer Treatments and Mutations
- Statistical Methods in Clinical Trials
- Genital Health and Disease
- Urological Disorders and Treatments
- Bladder and Urothelial Cancer Treatments
- Colorectal Cancer Screening and Detection
- Renal cell carcinoma treatment
- Liver Disease Diagnosis and Treatment
- Metastasis and carcinoma case studies
Clinical Centre of Kragujevac
2018-2024
University of Kragujevac
2018-2024
Background/Objectives: Palladium(II) complexes are promising anticancer agents with potential advantages over platinum drugs. This study aimed to synthesize and characterize three novel Pd(II) (2a–c) Schiff base ligands derived from salicylic acid amine scaffolds, evaluate their antitumor activity against prostate cancer cells. Methods: The were synthesized structurally characterized. Cytotoxicity was tested on two human cell lines (PC-3, DU-145) healthy fibroblasts (MRC-5). Apoptosis...
Introduction/Objective. The use of serum prostate-specific antigen (PSA) test has dramatically increased the number men undergoing prostate biopsy. However, best possible strategies for selecting appropriate patients biopsy have yet to be defined. aim study was develop a classification and regression tree (CART) model that could used identify with significant cancer (PCa) on in referred due abnormal PSA, digital rectal examination (DRE) findings, or both, regardless PSA level. Methods. data...
This case report presents a unique instance of small bowel perforation caused by solitary metastasis from renal cell carcinoma (RCC), rare and complex clinical scenario. The patient, 59-year-old male with history RCC treated nephrectomy four years prior, presented acute abdomen symptoms. Emergency diagnostic procedures identified significant lesion in the intestine. Surgical intervention revealed perforated jejunal segment due to metastatic RCC. Postoperatively, patient developed...
Abstract Serum prostate-specific antigen (PSA) testing increases the number of persons who undergo prostate biopsy. However, best possible strategy for selecting patients biopsy has not yet been defined. The aim this study was to develop a classification and regression tree (CART) decision model that can be used predict significant cancer (PCa) in course with serum PSA levels 10 ng/ml or less. following clinicopathological characteristics had undergone ultrasound-guided transrectal were...
Introduction/Objective. Prostate Health Index (PHI)-based nomograms were created by Lughezzani et al. (2012) and Zhu (2015) for predicting prostate cancer (PCa) at extended biopsy. The aim of the study was to externally validate two in Serbian population. Methods. This retrospective comprised 71 patients irrespective digital rectal examination (DRE) findings, with prostate-specific antigen level < 10 ng/ml, who had undergone biopsies, PHI testing. Data collected accordance previous...
Introduction/Objective. The precursor prostate-specific antigen (proPSA) especially its isoform p2PSA is useful in the detection of prostate cancer (PCa). However, prediction value different derivatives remains unclear. aim study was to compare performance p2PSA, percentage free PSA (%p2PSA), health index (Phi), and one dimension-adjusted index, density (p2PSAD), with each other for PCa patients serum 10 ng/ml or less. Methods. This prospective included who had undergone ultrasound-guided...
Abstract Screening has dramatically changed the distribution of mean age, stage and grade prostate cancer (PCa) at diagnosis. However, regional-level data that characterize contemporary PCa patients are limited. The aim study was to ascertain main clinical pathological characteristics present time in circumstances opportunistic testing. High-grade according serum specific antigen (PSA), volume prostate, PSA density (PSAD), digital rectal examination (DRE) number positive cores biopsies...