A5015651794- Digital Platforms and Economics
- Consumer Market Behavior and Pricing
- Corrosion Behavior and Inhibition
- Simulation Techniques and Applications
- Concrete Corrosion and Durability
- Auction Theory and Applications
- Retinal Diseases and Treatments
- Retinal and Optic Conditions
- Complex Systems and Decision Making
- Flexible and Reconfigurable Manufacturing Systems
- Information and Cyber Security
- Distributed systems and fault tolerance
- AI-based Problem Solving and Planning
- Advanced Database Systems and Queries
- Scheduling and Optimization Algorithms
- Business Process Modeling and Analysis
- Retinal Imaging and Analysis
- Systemic Lupus Erythematosus Research
- Economic theories and models
- Multi-Agent Systems and Negotiation
- Privacy, Security, and Data Protection
- Merger and Competition Analysis
- Service-Oriented Architecture and Web Services
- Game Theory and Applications
- Urinary Bladder and Prostate Research
Intas Pharmaceuticals (India)
2018-2025
Purdue University West Lafayette
2007-2017
National Law University Jodhpur
2013
Maharshi Dayanand Saraswati University
2012
Chemical Synthesis Lab
2010
Government College of Science
2009
State Street (United States)
2007
Kranj School Centre
2007
United States Department of Homeland Security
2005-2006
St Petersburg University
2000-2004
In this research note, we examine the design, development, validation, and use of virtual worlds. Our purpose in doing so is to extend design science paradigm by developing a set principles applicable context environments, particularly those using agent-based simulation as their underlying technology. central argument that worlds comprise new class information system, one combines structural aspects traditional modeling systems concert with emergent user dynamics supporting knowledge...
<b><i>Background:</i></b> This subgroup analysis of the RE-ENACT study evaluates effectiveness Razumab® (the world’s first biosimilar ranibizumab by Intas Pharmaceuticals Ltd.) in Indian patients with retinal vein occlusion (RVO). <b><i>Methods:</i></b> The data on RVO who had received ≥3 injections between January and August 2016 were analyzed. Endpoints were: improvement best corrected visual acuity (BCVA), a decrease central macular...
168 Background: Docetaxel combined with prednisone is the first line chemotherapy to improve overall survival in metastatic castration resistant prostate cancer (mCRPC). Nanosomal docetaxel lipid suspension (NDLS) a novel formulation that eliminates need for polysorbate 80 and ethanol, reducing infusion-related reactions requirement steroid premedication. This phase 4 trial aims assess efficacy safety of NDLS patients mCRPC. Methods: In this multicenter, open-label, single-arm trial,...
Weight loss and thermometric methods have been used to study the corrosion inhibition of mild steel in acidic solution (HCl H 2 SO 4 ) by Schiff's bases viz.N-(4-N,N-dimethylaminobenzal)-p-anisidine (SB 1 ), N-(4-N,N-dimethylaminobenzal)-p-toluidine N-(4-N,N-dimethylaminobenzal)-2,4-dinitroaniline 3 ).The efficiencies compared with those parent amines from which derived.Results observed these two are good agreement found be dependent on concentrations inhibitors as well acids.Inhibition...
The REal life assessmENt of safety And effeCTiveness Razumab (RE-ENACT) and long-term RE-ENACT 2 retrospective studies have evaluated the use Razumab™ (world's first biosimilar ranibizumab) in retinal disorders Indian patients. This report presents subgroup analysis from study patients with wet age-related macular degeneration (wet AMD).Medical charts administered ranibizumab injections as PRN treatment regimen between September 2015 June 2018, at 17 centers across India, were reviewed....
Endoxifen is a protein kinase C inhibitor. The objective of the present phase III study was to demonstrate safety and efficacy endoxifen in treating bipolar I disorder (BPD I) patients.A multicenter, double-blind, active-controlled conducted using daily dose 8 mg compared 1000 divalproex, current standard treatment, patients with BPD acute manic episodes with/without mixed features. primary endpoint our mean change total Young Mania Rating Scale (YMRS) score at day 21.Endoxifen (n = 116)...
Modeling and simulation environments are needed to support decision making in Navy Warfighters, which emergent systems that pose a challenge operations management. Ships consist of complex interconnected such as the infrastructure, crew, workflow. A system-of-systems approach using agent-based modeling is applied here develop workflow simulations involving ship's crew conducting routine maintenance, watch duty, reporting functions. Simple models used describe basic behavioral traits...
In this article, we analyze the economics of a monopoly firm selling and renting packaged software product by employing an intertemporal pricing game to model firm's strategy. The models as two versions; first version is available in period second, revised version, second period. benefits from consumer reports bugs requests for additional features. This modeled using delayed network externalities that take effect only We observe introduction rental leads increase profits. also find profits...
With the advent of Internet, and minimal information technology requirements a trading partner to join an exchange, number sellers who can qualify participate in online exchanges is greatly increased. We model competition between two with different unit costs production capacities responding buyer demand. The resulting mixed-strategy equilibrium shows that one has normal high price random sales, while other seller continuously randomizes its prices. It also brings out inherent advantages...
The REal life assessmENt of safety And effeCTiveness Razumab 2 (RE-ENACT 2) study evaluated the long-term effectiveness biosimilar ranibizumab. We present subgroup analysis patients with retinal vein occlusion (RVO).Data who received pro re nata (PRN) ranibizumab (November 2015 to December 2018, 17 centers) were analyzed. Endpoints change from baseline in best corrected visual acuity (BCVA, Snellen's/logMAR), central subfield thickness (CSFT), intraocular pressure (IOP), and proportions...
The food industry has many points of vulnerability in its supply chain. It currently lacks integrated crisis management and response programs to understand the importance decision-making during aftermath a bioterrorist attack on supply. Computer simulations have been used successfully other industries as training analysis tools. This paper describes an agent-based simulation for defense analysis. Production information, consumption patterns, morbidity/mortality rates, recall costs additional...
Abstract Background Razumab™ (world’s first biosimilar ranibizumab) is approved for several macular disorders including wet age-related degeneration (AMD). We evaluated the safety and efficacy of ranibizumab in AMD. Methods This prospective, multicentre, rAnibizumab bioSimilar Safety Efficacy postmarkeTing (ASSET) study enrolled patients aged ≥ 50 years with AMD having best-corrected visual acuity (BCVA) between 20/40 20/320. The received intravitreal 0.5 mg every 4 weeks 24 weeks. endpoints...
The article summarizes extant research on context effects and choice theories in a straightforward fashion. are used as benchmarks to compare six theories. include similarity, attraction, compromise, reference point effects. considered simple scalability model, random utility elimination by aspects strategy switching models, componential connectionist network model of choice. discusses the implications each for consumer behavior, suggests that should depend characteristics products,...
Multi-organizational collaborative decision making in high-magnitude crisis situations requires real-time information sharing and dynamic modeling for effective response. Information technology (IT) based support tools can play a key role facilitating such We explore one promising class of on machine learning, known as vector machines (SVM), which have the capability to dynamically model analyze processes. To examine this capability, we use case study with design science approach evaluate...
Abstract Background COVID-19 hyper-immune globulin (HIG) solution is a human plasma-derived, highly-purified, concentrated, virus-inactivated preparation of neutralizing antibodies (NAbs) against COVID-19. Methods This was randomized, two-arm, controlled, multi-center trial to evaluate the efficacy and safety HIG in patients who were hospitalized with moderate-severe infection. Results A total 60 randomized (30 each arm). Overall, well-tolerated without any serious treatment-emergent adverse...
Weight loss technique has been used to study the corrosion inhibition efficiency of tin in HNO3 solution by using leaves and stem extract different varieties Holy Basil viz. ocimum basilicum (EB),, cannum (EC) sanctum (ES). The results show that all under are good inhibitors, among which EB is most effective. Corrosion increases with increasing concentration inhibitor it also solution. Inhibition was found maximum up 96.19% for 0.6% extract.