A5013236103- Phytochemistry Medicinal Plant Applications
- Plant biochemistry and biosynthesis
- Ginger and Zingiberaceae research
- Essential Oils and Antimicrobial Activity
- Pesticide Residue Analysis and Safety
- Enzyme Catalysis and Immobilization
- Plant-Derived Bioactive Compounds
- Natural product bioactivities and synthesis
- Environmental and Ecological Studies
- Microbial Metabolic Engineering and Bioproduction
- Business, Innovation, and Economy
- Analytical Chemistry and Chromatography
- Educational Innovations and Technology
- Analytical Methods in Pharmaceuticals
- Complementary and Alternative Medicine Studies
- Occupational Health and Safety in Workplaces
- Regional Development and Innovation
- Educational Research and Science Teaching
- Scientific Measurement and Uncertainty Evaluation
- Phytochemistry and Bioactivity Studies
- Dye analysis and toxicity
- Diverse Applied Research Studies
- Traditional and Medicinal Uses of Annonaceae
- Natural Compounds in Disease Treatment
- Seaweed-derived Bioactive Compounds
Fundação Oswaldo Cruz
2004-2022
Universidade do Estado do Rio de Janeiro
2020
Empresa de Pesquisa Agropecuária e Extensão Rural de Santa Catarina
2020
National University of San Marcos
2019
Fundação Instituto de Pesca do Estado do Rio de Janeiro
2007
Natura (Brazil)
2007
Universidade Estadual de Campinas (UNICAMP)
2002
Universidade Federal do Rio de Janeiro
2002
Perillyl derivatives are increasingly important due to their flavouring and antimicrobial properties as well potential anticancer agents. These terpenoid species, which present in limited amounts plants, may be obtained via bioconversion of selected monoterpene hydrocarbons. In this study, seventeen yeast strains were screened for ability oxidize the exocyclic methyl group p-menthene moiety limonene into perillic acid. Of tested, highest efficiency was observed Yarrowia lipolytica ATCC...
BY HIGH RESOLUTION GAS CHROMATOGRAPY.Quantitative GC-FID was evaluated for analysis of methylated copaiba oils, using trans-(-)-caryophyllene or methyl copalate as external standards.Analytical curves showed good linearity and reproducibility in terms correlation coefficients (0.9992 0.996, respectively) relative standard deviation (< 3%).Quantification sesquiterpenes diterpenic acids were performed with each standard, separately.When compared the integrator response normalization,...
A new chemotype of the aromatic Verbenaceae species Lippia alba Mill. N. E. Br. from southeastern Brazil has recently been shown to have a high content linalool in leaf essential oil. Vegetative propagation this was conducted at six different locations Brazil, and variation optical purity oils were verified. Yields (0.6−0.9%, hydrodistillation), chemical composition, content, all plants compared, using GC−FID, GC−MS, chiral chromatography, retention index calculation. No plant exceeded...
ABSTRACT Introduction Non‐volatile oleoresins from neotropical Burseraceae are traditionally used for craft, technological and medicinal purposes. The crude resin is usually sold in popular markets of the forest communities. Adding value to this rainforest raw material requires establishing its composition. Objective To analyse composition different species establish a minimally reproducible profile by gas chromatography, order parameterise quality control. Methodology Crude oleoresin...
The essential oils of six species Protium (Burseraceae), collected near Manaus, Amazon, were extracted by hydrodistillation and analysed GC – MS. Resins from four yearly, two represented more than one tree. All found to be entirely monoterpenoid in constitution characterized the predominance p-cymene α- β-phellandrene. composition fresh exudates is associated with increasing content α-pinene unsaturated p-menthanes. Copyright © 2000 John Wiley & Sons, Ltd.
The bioconversion of the hydrophobic and volatile limonene to perillic acid, a potential anticancer agent, by yeast Yarrowia lipolytica was studied in two steps. Firstly, experimental design used for process optimization using high-purity as substrate secondly orange essential oil containing 89.1% under previously optimized conditions. Limonene concentration pH were identified fractional factorial significant factors central composite design. Under conditions (0.16% (v/v) limonene; 6.9), 24...
Las comunidades campesinas y nativas son instituciones cuyas referencias historicas datan de mucho antes que los Estados modernos constituidos en America Latina durante el siglo XIX. Estas instituciones, XX, se convirtieron lugares clasicos investigacion academica enunciacion para antropologos tanto nacionales como extranjeros. El texto reseno forma parte esa reflexion e ira a parar anaqueles las bibliotecas, constituyendose asi testimonio un momento historico mencionadas. En razon la...
Abstract The high‐speed countercurrent chromatography technique was employed to isolate two major compounds from the leaf essential oil of Eugenia uniflora L. (Myrtaceae). volatile extract obtained by hydrodistillation analyzed gas coupled with flame ionization detection and mass spectrometry shown be almost exclusively constituted sesquiterpenes, in which (+/‐)‐selina‐1,3,7(11)‐trien‐8‐one (A) epoxide (B) were largely predominant. These separated submitting crude using hexane/acetonitrile...
A espécie Alpinia zerumbet (Zingiberaceae) tem amplo emprego na medicina tradicional e popular como diurética anti-hipertensiva. O Formulário de Fitoterápicos da Farmacopeia Brasileira padroniza o uso A. forma tintura, indicada para tratamento hipertensão arterial leve. presente estudo objetivo avaliar a influência técnica extração do tamanho partícula material vegetal no processo extrativo compostos fenólicos totais das folhas zerumbet. Folhas secas foram extraídas com etanol:água (7:3...
Perillic acid can be obtained from microbial oxidation of the exocyclic methyl group limonene. Due to pharmacological potential such a metabolite, biotransformation processes leading its synthesis have been approached in recent studies. A robust analytical method is needed assess performance An was developed and validated determine perillic supernatants yeast-induced bioconversion limonene, involving gas chromatography (GC) an acid-induced precipitation during sample preparation. GC analysis...
The specific legislation for the production and use of medicinal plants has been improved in Brazil, as far its continuous evolution is concerned.However, there still a failure at surveillance quality these products.This work showed panorama some espinheira-santa samples (Maytenus ilicifolia) purchased from local markets, through moisture, contaminants, epicatechin total tannin content.Contaminants were found above maximum limits admitted 89 % (stems, mosses lichens) allowable.Regarding...
Stonebreaker is a medicinal plant traditionally used for the treatment of urolithiasis among other illnesses. However, several species genus Phyllanthus L. are called “quebra-pedra” (stonebreaker) by general population in Brazil, due to taxonomic similarities, although use with low content active compounds may lead less effective treatment. P. niruri and tenellus recognized as stonebreaker Brazilian Pharmacopoeia, Ministry Health included spp list plants recommended research...
In this report, a rapid and selective analytical method for the determination of monoterpenes in Alpinia zerumbet essential oil (AZEO) by gas chromatography (GC) flame ionization detection (FID) was developed, optimized validated.The suitability six different capillary columns investigated polarity phase constants calculated based on methodology proposed Rohrschneider McReynolds.The most suitable column then used central composite design applying following GC factors to investigate responses...
As constituições lipídicas das sementes onze espécies de Leguminosae da Amazônia Central, Acosmium nitens Yakovl, Bauhinia splendens Kunt, Caesalpinia ferrea Martius var. ferrea, Clathrotropis nitida (Benth.) Harms., Cynometria spruceana Benth., Macrolobium acaciifolium Ormosia excelsa Parkia discolor Peltogyne venosa (Vahl.) Stryphnodendron guianense Vatairea guianensis Aubl. foram determinadas. Os componentes individuais dos óleos analisados por cromatografia em fase gasosa acoplada à...
The Brazilian National Medicinal Plants and Herbal Medicines Programme provides for the distribution of herbal medicines in all local municipal, state federal health services. Alpinia zerumbet (Pers.) B.L. Burtt & R.M.Sm. is traditionally employed to treat hypertension. Formulary Pharmacopoeia lists as a diuretic treatment mild However no chromatographic method quality control described. Since flavonoids are involved pharmacological activity, HPLC has been developed analysis aqueous extract,...