A5018474161- Radiomics and Machine Learning in Medical Imaging
- Lung Cancer Diagnosis and Treatment
- Medical Imaging Techniques and Applications
- Advanced Radiotherapy Techniques
- Cerebrovascular and Carotid Artery Diseases
- Intracranial Aneurysms: Treatment and Complications
- Traumatic Brain Injury and Neurovascular Disturbances
- Lung Cancer Treatments and Mutations
- Fetal and Pediatric Neurological Disorders
- Cancer, Hypoxia, and Metabolism
- Advanced Neuroimaging Techniques and Applications
- Advanced MRI Techniques and Applications
The Netherlands Cancer Institute
2015-2020
Princess Margaret Cancer Centre
2017
University Health Network
2017
Radboud University Nijmegen
2013
Radboud University Medical Center
2013
In locally advanced lung cancer, established baseline clinical variables show limited prognostic accuracy and 18F-fluorodeoxyglucose positron emission tomography (FDG PET) radiomics features may increase for optimal treatment selection. Their robustness added value relative to current factors are unknown. Hence, we identify robust independent PET that have complementary in predicting survival endpoints. A 4D dataset (n = 70) was used assessing the repeatability (Bland-Altman analysis)...
To assess the impact of a standardized delineation protocol and training interventions on PET/CT-based target volume (TVD) in NSCLC multicenter setting.Over one-year period, 11 pairs, comprised each radiation oncologist nuclear medicine physician with limited experience TVD for from nine different countries took part program through an International Atomic Energy Agency (IAEA) study (NCT02247713). Teams delineated gross tumor primary tumor, during after interventions, according to provided...
Patients with stage III non-small-cell lung cancer (NSCLC) treated chemoradiotherapy (CRT) in low- and middle-income countries (LMIC) continue to have a poor prognosis. It is known that FDG PET/CT improves staging, treatment selection target volume delineation (TVD), although its use has grown rapidly, it still not widely available LMIC. CRT often used as sequential treatment, but be more effective when given concurrently. The aim of the PERTAIN study was assess impact introducing...
In 14 patients (eight men, six women; mean age 58 [31-72] years) with intracranial aneurysm (basilar artery in nine, anterior branches five) the was occluded by electrically detachable platinum coils, advanced into introduced via a percutaneously catheter system, under local anaesthesia and fluoroscopic control. Ten had acute subarachnoid haemorrhage (stage II-IV). two several sessions were required before complete occlusion achieved. one patient, basilar aneurysm, aneurysmal wall perforated...
Fig 2. ADC in prostate and dose painted for Cim scenario. ConclusionGleason driven painting cancer using ADC-MRI is feasible to reduce the average dose.The reduction strongly dependent on minimum assigned voxels with G<6.
ESTRO 37 S546Gy, >2-5 Gy, >5-10 >10-15 and >15 Gy (Figure 1).Six patients had received WBRT (30 Gy) (N=4), SRS (N=2), or both (N=2) within one year prior to MR baseline of current investigated lesions.Maps Cerebral Blood Volume (CBV), Flow (CBF), vessel caliber relative oxygenation status (∆SO2) were obtained by conventional perfusion MRI VAI.Regions enhancing lesion edema identified on T1w post contrast FLAIR images, respectively.Binned dose distributions, ROIs all coregistered the...