Pınar Kürsüz Köseoğlu

ORCID: 0000-0003-4681-0968
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Research Areas
  • Genomics, phytochemicals, and oxidative stress
  • Bone health and osteoporosis research
  • Shoulder Injury and Treatment
  • Antibiotic Resistance in Bacteria
  • Musculoskeletal synovial abnormalities and treatments
  • Glutathione Transferases and Polymorphisms
  • Plant and Fungal Interactions Research
  • Peripheral Nerve Disorders
  • Nutrition and Health in Aging
  • Genomic variations and chromosomal abnormalities
  • Total Knee Arthroplasty Outcomes
  • Cardiovascular Disease and Adiposity
  • Adipose Tissue and Metabolism
  • Adipokines, Inflammation, and Metabolic Diseases
  • Antioxidant Activity and Oxidative Stress
  • Osteoarthritis Treatment and Mechanisms
  • Bacterial biofilms and quorum sensing
  • Exercise and Physiological Responses
  • Body Composition Measurement Techniques
  • Estrogen and related hormone effects
  • Pharmaceutical and Antibiotic Environmental Impacts
  • Chromatin Remodeling and Cancer
  • Congenital heart defects research
  • Epigenetics and DNA Methylation
  • Bone Tumor Diagnosis and Treatments

Istanbul University
2013-2024

HUN-REN Institute of Experimental Medicine
2021

Istanbul Yeni Yüzyıl University
2019

İstanbul Kanuni Sultan Süleyman Eğitim ve Araştırma Hastanesi
2016

Objective: Neuroinflammation is involved in the pathology of Alzheimer's disease (AD).Peripheral levels various inflammatory cytokines are altered during AD pathogenesis.This study aimed to examine role peripheral inflammation pathogenesis by measuring serum and gene expression specific patients.Therefore, we analyzed interleukin-6 (IL-6) transforming growth factor-beta 1 (TGF-β1) mRNA expressions IL-6 tumor necrosis factor-alpha (TNF-α) blood mononuclear cells patients controls.Materials...

10.4274/tji.galenos.2024.76598 article EN cc-by-nc-nd Turkish Journal of Immunology 2024-05-09

[Purpose] There are many types of hyaluronic acid preparations, but no clear data available about which preparations is more effective. The aim this trial was to investigate the effectiveness different on pain and function inpatients with knee osteoarthritis. [Subjects Methods] All patients were diagnosed by clinical examination x-ray. Ostenil PLUS® injected into 28 (group 1, 1.6 million daltons), MONOVISC® 2, 2.5 daltons) 46 patients. Demographic Western Ontario McMaster Universities...

10.1589/jpts.28.3036 article EN Journal of Physical Therapy Science 2016-01-01

BACKGROUND: Carpal tunnel syndrome (CTS) is a commonly seen peripheral nerve mononeuropathy. Corticosteroid injection within the carpal among conservative treatment options. The exact mechanism of action steroids not fully clear; decreased inflammation surrounding nerves or tend ons thought to be main effect. Lidocaine has been shown have anti-inflammatory effects on certain cells (monocytes, macrophages, neutrophils etc.). aim this study evaulate efficacy lidocaine as alternative...

10.3233/bmr-150477 article EN Journal of Back and Musculoskeletal Rehabilitation 2016-12-27

Aim:Host factors are known to modulate virulence, antibiotic susceptibility and growth of bacteria. In the present study we aimed investigate effect human insulin glucose on expression mar regulon (marA, marR, ompF, acrA, acrB tolC) E. coli SPC105. Material Methods:E. SPC105 was grown in tryptic soy broth (TSB-control) TSB containing 20 µU/mL insulin, 200 0.1% + glucose. Growths were determined via turbidimetric method. Quantitative polymerase chain reaction (qPCR) used determine gene...

10.18663/tjcl.459417 article EN Turkish Journal of Clinics and Laboratory 2019-05-06

<h3>Background</h3> One-third radius (33% radius) bone mineral density (BMD) measurements of the non-dominant forearm using dual-energy X-ray absorptiometry (DXA) may be used for diagnosis osteoporosis in certain circumstances. <h3>Objectives</h3> The aim this study was to investigate ability radial speed sound (SOS) identifying at as measured by DXA. <h3>Methods</h3> Both 1/3 BMD and SOS were 128 women aged between 21 79 years DXA (Hologic QDR® 4000) a multi-site quantitative ultrasound...

10.1136/annrheumdis-2013-eular.903 article EN Annals of the Rheumatic Diseases 2013-06-01

Objective: The etiology of Alzheimer's disease (AD) is affected via oxidative stress. Antioxidant enzymes are extremely important in preventing reactive oxygen species (ROS) causing damage the cell. changes expression levels oxidant and antioxidant genes key factors cell response to As a result, this study investigated change specific stress related (solute carrier family 7 member 11 (SLC7A11), glutathione peroxidase 4 (GPX4), catalase (CAT) acylcoa synthetase long chain (ACSL4)) peripheral...

10.26650/experimed.2021.911956 article EN Experimed 2021-08-27
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