Nidhi Girdhar

ORCID: 0000-0003-4690-4796
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About
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Research Areas
  • Tuberculosis Research and Epidemiology
  • Diagnosis and treatment of tuberculosis
  • Asthma and respiratory diseases
  • Mycobacterium research and diagnosis
  • Infectious Diseases and Tuberculosis
  • Respiratory Support and Mechanisms
  • Hematological disorders and diagnostics
  • Glutathione Transferases and Polymorphisms
  • IL-33, ST2, and ILC Pathways
  • Allergic Rhinitis and Sensitization
  • Tracheal and airway disorders
  • Cardiac Arrest and Resuscitation
  • Diverse Scientific Research Studies
  • Mechanical Circulatory Support Devices
  • Magnesium in Health and Disease
  • Antifungal resistance and susceptibility
  • Respiratory and Cough-Related Research
  • Dermatology and Skin Diseases
  • Selenium in Biological Systems
  • Orthopedic Infections and Treatments
  • Dysphagia Assessment and Management
  • Genomics, phytochemicals, and oxidative stress
  • Whipple's Disease and Interleukins
  • Trace Elements in Health
  • Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis

NKP Salve Institute of Medical Sciences and Lata Mangeshkar Hospital
2023-2025

Government Medical College
2019-2023

Chest Diseases Hospital
2023

Government Medical College and Hospital
2022

Asthma is a heterogeneous disease characterized by chronic airway inflammation. It defined the history of respiratory symptoms such as wheeze, shortness breath, chest tightness, and cough that vary over time intensity, together with variable expiratory airflow limitation. A personal or family allergy factor most strongly associated development asthma. Our primary aim was to investigate interleukin-4 receptor α (IL-4Rα) polymorphism determine whether presence R576 IL-4Rα allele asthma...

10.4081/monaldi.2025.3095 article EN cc-by-nc Monaldi Archives for Chest Disease 2025-01-27

Extrapulmonary tuberculosis (EPTB) is a multifaceted disease that could potentially impact nearly all organs. Current global data indicate significant variation in the proportion of EPTB among cases, ranging from 15% to 53%. Clinicians India express concerns about efficacy cartridge-based nucleic acid amplification test (CBNAAT) EPTB, as its yield frequently does not align with findings World Health Organization meta-analysis. Hence, present study was conducted evaluate diagnostic CBNAAT at...

10.4081/monaldi.2025.3238 article EN cc-by-nc Monaldi Archives for Chest Disease 2025-03-06

Abstract Chronic obstructive pulmonary disease (COPD) is commonly characterized by shortness of breath, coughing or expectoration. Smoking the leading cause COPD development, but only a small percentage smokers develop symptoms, implying genetic component. Glutathione S ‐transferase enzymes are responsible for detoxifying cigarette smoke components. The role glutathione T1 (GSTT1) and S‐transferase M1 (GSTM1) gene polymorphism was assessed with susceptibility associated clinical parameters...

10.1113/ep091339 article EN cc-by Experimental Physiology 2023-11-10

Tuberculosis is a communicable infective disease caused by Mycobacterium tuberculosis (MTB). The most commonly involved organ the lung (Pulmonary tuberculosis), however, MTB can affect any other than lungs; in this cases, it known as Extrapulmonary (EPTB), which lead to significant morbidity and mortality. Patients with EPTB rarely develop ankle or foot arthritis, usually either misdiagnosed diagnosed very late, leading complications. Early diagnosis timely treatment are important prevent...

10.4081/cdr.12.12267 article EN Chest Disease Reports 2024-01-30

Mycobacterium tuberculosis causes an infectious bacterial disease frequently affecting the lungs. With two fatalities from (TB) occurring every three minutes, India has highest burden. The etiology of TB been linked to IL-8 and IL-4RA. Thus, impact IL4RAQ576R IL8 gene polymorphisms on susceptibility was assessed. 301 healthy patients participated in a cross-sectional study. Polymerase chain reaction-restriction fragment length polymorphism performed identify genotype +781 C/T polymorphism....

10.4081/monaldi.2023.2594 article EN cc-by-nc Monaldi Archives for Chest Disease 2023-08-10

Allergic rhinitis (AR) is a chronic allergen specific, IgE-mediated hypersensitivity disorder which significantly impairs the quality of life in affected patients. Many aeroallergens and molds are responsible for AR. This study was conducted to find prevalence Aspergillus fumigatus skin patients AR by prick test (SPT). 150 clinically diagnosed visiting our OPD were enrolled. Skin f. done SPT all enrolled Chi square Student’s t-test applied statistical analysis. Out patients, 60 (40%)...

10.4081/monaldi.2021.1416 article EN cc-by-nc Monaldi Archives for Chest Disease 2021-03-09

Background: Tuberculosis (TB) is one of the common communicable disease affecting human beings since ancient times. Though effective chemotherapy emerged during 20th century had raised hope towards eliminating TB burden, it still remains as a distant goal. Awareness about among close contacts active paramount importance in preventing its spread and promoting early diagnosis treatment. This study aimed to assess knowledge tuberculosis caregivers patients.Methods: was cross sectional that...

10.18203/2320-6012.ijrms20194993 article EN International Journal of Research in Medical Sciences 2019-10-24

Mediastinal lymphadenopathy is often associated with tuberculosis, especially in a high burden country like India. We present case of an asymptomatic female, who had mediastinal and middle lobe collapse, both which pointed towards diagnosis tuberculosis. Patient was later diagnosed as allergic bronchopulmonary aspergillosis (ABPA) on basis clinical, radiological serological findings. Hence, even background bronchial asthma, ABPA should be kept differential patients presenting

10.4081/monaldi.2021.1696 article EN cc-by-nc Monaldi Archives for Chest Disease 2021-03-08

Abstract Introduction: When arterial oxygen pressure is < 60 mmHg and carbon dioxide normal or low, hypoxemic respiratory failure (type I) occurs. Acute patients who get noninvasive ventilation (NIV) had a much lower risk of morbidity fatality. Materials Methods: On 55 subjects acute (AHRF) with NIV support, an observational study was performed at tertiary care hospital. All the cases were assessed clinically along evaluation blood gas, ROX index, chest X-ray. Patient re-accessed end 24...

10.4103/injms.injms_85_23 article EN cc-by-nc-sa Indian Journal of Medical Specialities 2023-10-01

1. Pace M, Dapoto A, Surace et al. Tracheal diverticula: A retrospective analysis of patients referred for thoracic CT. Medicine (Baltimore). 2018;97(39):e12544. doi:10.1097/MD.0000000000012544 CrossRef Google Scholar

10.18332/pne/146642 article EN cc-by-nc Pneumon 2022-04-19
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