The main symptoms of depression, a chronic mental illness, include sadness, low self-esteem, and diminished sense enjoyment in life. Many factors have been suggested to be associated with one which is testosterone men. serotonin reuptake inhibitor fluoxetine (FLU), used treat has reported potentially detrimental effects on spermatogenesis rats after long-term use. multimodal antidepressant vortioxetine (VTX) offers new promise for the treatment depression. unpredictable mild stress (CUMS)...

Aim: Osteochondromas are the most common, benign, primary bone tumors with a medullary cavity, covered hyaline cartilage arising from juxtaepiphyseal region of bone. Although they often asymptomatic, operated on due to cosmetic unhappiness, symptoms pressure adjacent tissues, pain, and rarely malignant transformation. In this study, we aimed retrospectively evaluate our cases diagnosed osteochondroma, which presented different localization clinical findings, along conventional cases, present...

Background Increasing evidence suggests that early life stress (ELS) and neuroinflammation are associated with the pathophysiology of depression. The purpose this study was to determine effects Vortioxetine (VOR), a novel antidepressant, on ELS-induced behavioral changes neuroinflammation.

The aim of this study was to evaluate whether adenomyosis had an effect on myometrial tumor invasion, stage the disease, and survival in endometrial cancer.Endometrial cancer patients encountered between 2007 2016 were identified from pathology records. Patients who underwent suboptimal surgical or medical treatment with insufficient clinical data excluded. diagnosed as having concurrent constituted group. Control group randomly selected a paired design according grades group, for each...

Background: IMP3, a member of insulin-like growth factor II m RNA binding protein family, seems to be promising in the diagnosis carcinomas many organs as well malignant melanomas and some sarcomas.It is postulated that it might marker malignancy.The results few prior studies indicate IMP3 has potential useful distinguishing benign tumors thyroid.Aims: We aimed evaluate immunohistochemical expression non-neoplastic nodules thyroid.Study Design: Diagnostic accuracy study.Methods: Overall, 92...

The aim of this study was to investigate the effects remote ischemic conditioning on ischemia-reperfusion injury in rat muscle flaps histopathologically and biochemically.Thirty albino rats were divided into 5 groups. No procedure performed group 1, only blood samples taken. A gracilis flap elevated all other Microclamps applied vascular pedicle for 4 hours order achieve tissue ischemia. In 2, no additional performed. groups 3, 4, 5, right hind limb used 3 cycles minutes each (total, 30...

To evaluate the expression of stanniocalcin-1 (STC-1) and to investigate correlation STC-1 with estrogen receptor (ER), progesterone (PR) clinical parameters, histopathological findings prognostic factors in endometrioid endometrial cancer (EEC).In this retrospective study, (cytoplasmic), ER (nuclear), PR (nuclear) stainings were applied tissue microarray sections 89 EEC, 27 intraepithelial neoplasia (EIN), 21 normal endometrium (NE). Prognostic such as age, tumor size, depth myometrial...

Objectives: This study aims to evaluate which of the histomorphological criteria defined in labial salivary gland biopsy are more valuable diagnosing Sjögren’s syndrome (SS) and examine its correlation with clinical laboratory findings. Patients methods: Between January 2005 2019, a total 927 patients (104 males, 823 females; mean age: 51 years; range, 19 85 years) who underwent minor biopsies suspicion SS were retrospectively analyzed. The American College Rheumatology (ACR)/European League...

Prenatal stress can negatively impact neonatal health, growth, and bonding with the mother. However, molecular basis of these modifications is not completely understood. The aim this experimental study was to test hypothesis that intrauterine exposure may contribute subsequent depression-like comorbidities associated neuroinflammation. Wistar Albino nulliparous female rats were divided into two groups (each, n = 6): controls pregnancy (Days 1 through 21). Two live rat pups (one one male)...

Background: Prostate-specific membrane antigen (PSMA) expression is encountered in tumor-associated neovascularization.Methods: PSMA-antibody was applied to the paraffin blocks of 51 patients who were diagnosed with squamous cell carcinoma larynx and underwent laryngectomy one lymph node dissection. The percentage vascular tumoral extratumoral stroma nodes intensity score epithelium evaluated divided into groups according level PSMA expression. Final determined by multiplying scores.Results:...

Introduction:To evaluate the role of HBME1, PAX8, CD56 and CITED1 in distunguishing benign lesions thyroid from malignant tumors different thyroid.Methods: The patients that underwent thyroidectomy between 2007 2013 were included to study.Patients with Nodular Hyperplasia:

Searchable abstracts of presentations at key conferences in endocrinology ISSN 1470-3947 (print) | 1479-6848 (online)

Liken planus deri, mukoz membranlar, sacli deri ve tirnagi tutabilen genellikle kronik seyreden inflamatuar bir hastaligidir. Klasik liken planusun karakteristik lezyonu birkac milimetre boyutlarinda mor renkli, duz yuzeyli, poligonal papullerdir predileksiyon bolgeleri; el bilegi, ayak lomber bolge ile oral genital mukozalardir (1). formu disinda anuler, atrofik, bulloz, hipertrofik, folikuler, lineer, mukozal, tirnak planusu gibi farkli klinik gorunumlerde varyantlari da vardir....

Olgumuzu Dowling

Foliküler müsinozis folikül epitelinde ve sebase glandlarda müsin adacıklarının gözlendiği bir durumdur. Histopatolojik bulguları birikiminin mikozis fungoides ile ayırtedebilmek çok zordur. Çocukluk çağında görülen foliküler müsinöz olgularının çoğunda spontan regresyon görülse de Hodgkin Lenfoma ilişkili olduğuna dair veriler bulunmaktadır. Bizde bu makalede çocukluk nadir olarak rastlanan olgusunu sunmayı amaçladık.

Tiroidin primer malign teratomu oldukça nadir görülen bir tümördür. Literatürde olgu sunumu ve serileri olarak bildirilmiştir. Malign tiroid teratomları agresif seyirli tümörlerdir. Bu sunumunda histopatolojik bulgular immünhistokimyasal yöntemler ile tanısını koyduğumuz 39 yaşında kadın hastadaki tiroidin teratomunu sunmayı amaçladık.

Giriş: Anjiomyolipom (AML) matür yağ dokusu, kalın duvarlı damar yapıları, düz kas dokusu ve melanin sentezleyen özel miyoid hücrelerin değişen oranlarda gözlendiği benign mezankimal bir tümördür. Bu makalede 2008-2018 yılları arasında bölümümüzde renal AML tanısı almış farklı klinik mikroskopik özellikleri olan olgular ile patolojide tanı koymada yararı olacak güncel bilgileri sunmayı amaçladık. Gereç Yöntemler: Tıbbı Patoloji Anabilim Dalımızda 15 Renal olgusu retrospektif olarak...