Ziya Akar

ORCID: 0000-0003-4706-8881
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About
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Research Areas
  • Meningioma and schwannoma management
  • Head and Neck Surgical Oncology
  • Pituitary Gland Disorders and Treatments
  • Neurofibromatosis and Schwannoma Cases
  • Sinusitis and nasal conditions
  • Intracranial Aneurysms: Treatment and Complications
  • Glioma Diagnosis and Treatment
  • Neurosurgical Procedures and Complications
  • Craniofacial Disorders and Treatments
  • Cerebrospinal fluid and hydrocephalus
  • Vascular Malformations Diagnosis and Treatment
  • Spinal Dysraphism and Malformations
  • Cerebral Venous Sinus Thrombosis
  • Spinal Hematomas and Complications
  • Trigeminal Neuralgia and Treatments
  • Cancer and Skin Lesions
  • Spine and Intervertebral Disc Pathology
  • Ophthalmology and Eye Disorders
  • Cervical and Thoracic Myelopathy
  • Teratomas and Epidermoid Cysts
  • Management of metastatic bone disease
  • Facial Nerve Paralysis Treatment and Research
  • Facial Trauma and Fracture Management
  • Sarcoidosis and Beryllium Toxicity Research
  • Immunotherapy and Immune Responses

Istanbul University-Cerrahpaşa
1994-2021

Istanbul University
2000-2015

Acıbadem Kadıköy Hospital
2005-2006

University of Illinois Chicago
1994-1995

Object The purpose of this study was to define the patterns drainage superior petrosal venous complex (SPVC) along petrous ridge in relation Meckel cave and internal acoustic meatus (IAM) delineate its effect on surgical exposures obtained subtemporal transtentorial retrosigmoid suprameatal approaches. Methods SPVC were characterized according their IAM based an examination 30 hemispheres. Subtemporal retro-sigmoid approaches performed three additional cadavers demonstrate pattern exposures....

10.3171/jns.2007.106.6.1041 article EN Journal of neurosurgery 2007-06-01

Intracranial epidermoid tumors are rare, potentially curable, benign lesions that sometimes associated with perioperative complications, and tend to recur if not completely removed. Histologically may also develop into highly malignant tumors. This study evaluated on 28 cases of intracranial tumor treated over a 13-year period by radical resection microneurosurgical techniques. The majority patients underwent computed tomography and/or magnetic resonance imaging within the first 24 hours...

10.2176/nmc.43.275 article EN cc-by-nc-nd Neurologia medico-chirurgica 2003-01-01

The objective of this study was to recognize the endoscopic anatomy orbital apex and medial wall understand pure endonasal approaches region their clinical applications. These basic information will facilitate our surgical procedures decrease rate complications.Five fresh adult cadavers were studied bilaterally (N = 10). We used Karl Storz 0- 30-degree 4-mm, 18-cm, 30-cm rod-lens rigid endoscopes in dissections. After cadaver specimen preparation, we approached each through nostril....

10.1097/scs.0b013e3181b0dc23 article EN Journal of Craniofacial Surgery 2009-09-01

We studied the intracranial portion of vertebral artery and its branches in 11 cadaveric specimens. evaluated course vessels their dimensions (external diameter length), as well relationships between each them. The was larger on ? left side two cases, right five equal both sides four cases. arteries joined other forming basilar at level pontomedullary junction 2 mm below it one case, 1 to 7 above six divided all into groups: medial lateral branches. Two major types were observed: anterior...

10.1080/01616412.1994.11740221 article EN Neurological Research 1994-06-01

✓ The arterial supply and the microanatomy of anterior surface medulla oblongata olive were studied in 11 cadaveric specimens, with investigation size, course, length arteries. Two distinct anatomical entities divide vascular this region: 1) pyramid, which is medulla; 2) olive, adjacent to lateral aspect pyramid. Primary vascularization pyramid was via small branches spinal artery, a branch vertebral artery. Minute perforators from artery found all specimens. Arterial varied by location: its...

10.3171/jns.1995.82.1.0097 article EN Journal of neurosurgery 1995-01-01

Objective: The objective of this study was to recognize the endoscopic anatomy clival region skull base and its neurovascular relations, which will make us able perform safer minimal invasive approaches with lower rate complications. Materials Methods: Six fresh cadavers were studied (n = 5). We approached clivus by performing binostril extended endonasal approach. After locating sphenoid sinus as a key point, vomer totally removed expose located inferiorly sinus. Mucosal incision is done...

10.1097/scs.0b013e3181c5a294 article EN Journal of Craniofacial Surgery 2010-01-01

Objectives: The objective of this study was to review the endoscopic anatomy anterior skull base, defining pitfalls endonasal approaches region. Recently, these are gaining popularity among neurosurgeons, and details highlighted from neurosurgeons' point view, correlated with demonstrative cases. Materials Methods: Twelve fresh adult cadavers were studied (n = 12). We used Karl Storz 0 30 degrees, 4 mm, 18- 30-cm rod lens rigid endoscope in our dissections. After preparation cadaveric...

10.1097/scs.0b013e3181d02420 article EN Journal of Craniofacial Surgery 2010-03-01

Increased vascular permeability, vasodilatation, neovascularization and free radical injury in malignant tumors adjacent normal tissues are believed to be mediated by nitric oxide (NO). High levels of neuronal synthase (nNOS) have been demonstrated cultured intracerebral cells. Our aim was investigate nNOS expression human glial assess its correlation with the histologic grade proliferative potential.Tissue specimens were obtained from 29 patients supratentorial astrocytomas [15 glioblastoma...

10.1179/174313208x319099 article EN Neurological Research 2008-07-31

Cytokine based immunotherapy has long been an exciting field for many investigators aiming to provide effective alternative treatment modality glioma management. Among these cytokines, interleukin-12 (IL-72) plays a crucial role in mediating inflammatory and antitumoral activity on the host defence. We have investigated therapeutic of systemic local delivery IL-12 C6 rat model compared two modalities.The donor cells were injected stereotactically 32 Wistar rats right frontal tumor formation...

10.1179/174313208x289516 article EN Neurological Research 2008-04-21

✓ Vertebrobasilar insufficiency (VBI) due to vertebral artery (VA) compression occurs in a significant number of patients. Rotational the VA usually below C-2, where is pinched during head rotation, leading thrombus formation and subsequent cerebellar infarction. Although this problem has been reported occur at atlantooccipital levels, review literature revealed no published cases point dural penetration, which located above membrane. The authors report case 30-year-old woman who presented...

10.3171/spi.2000.93.2.0300 article EN Journal of Neurosurgery Spine 2000-10-01
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