A5029636240- Advanced Chemical Sensor Technologies
- Gas Sensing Nanomaterials and Sensors
- Analytical Chemistry and Sensors
- Biosensors and Analytical Detection
- Diet, Metabolism, and Disease
- Electrochemical sensors and biosensors
- Diet and metabolism studies
- Forensic Toxicology and Drug Analysis
- Poisoning and overdose treatments
- Liver Disease Diagnosis and Treatment
- Metabolomics and Mass Spectrometry Studies
- Analytical Chemistry and Chromatography
- Cardiovascular and exercise physiology
- Heart Rate Variability and Autonomic Control
University Hospital of Zurich
2020-2023
University of Zurich
2021-2023
•It is debated whether fructose drives the metabolic syndrome or non-alcoholic fatty liver disease.•Fructose in a liquid form, within sugar-sweetened beverages, may impact metabolism.•Herein, consumption of beverages containing sucrose increased hepatic lipogenesis.•Increased lipogenic activity promote long-term perturbations. Background & aimsExcessive intake associated with de novo lipogenesis, blood triglycerides, and insulin resistance. We aimed to determine elicits specific effects on...
Mobile health technologies can provide information routinely and on demand to manage metabolic diseases (e.g., diabetes obesity) optimize their treatment exercise or dieting). Most promising is breath acetone monitoring track lipolysis complement standard glucose monitoring. Yet, accurate quantification of down parts‐per‐billion (ppb) difficult with compact mobile devices in the presence interferants at comparable higher concentrations. Herein, a low‐cost detector that quantifies end‐tidal...
Abstract Exhaled breath acetone (BrAce) was investigated during and after submaximal aerobic exercise as a volatile biomarker for metabolic responsiveness in high lower-fit individuals prospective cohort pilot-study. Twenty healthy adults (19–39 years) with different levels of cardiorespiratory fitness (VO 2peak ), determined by spiroergometry, were recruited. BrAce repeatedly measured proton-transfer-reaction time-of-flight mass spectrometry (PTR-TOF-MS) 40–55 min cycling post-exercise...
Non-invasive breath analysis with mobile health devices bears tremendous potential to guide therapeutic treatment and personalize lifestyle changes. Of particular interest is the volatile acetone, a biomarker for fat burning, that could help in understanding treating metabolic diseases. Here, we report hand-held (6 × 10 19.5 cm3), light-weight (490 g), simple device rapid acetone detection breath. It comprises tailor-made end-tidal sampling unit, connected sensor pump on-demand sampling, all...
Methanol poisoning outbreaks after consumption of adulterated alcohol frequently overwhelm health care facilities in developing countries. Here, we present how a recently developed low-cost and handheld breath detector can serve as noninvasive rapid diagnostic tool for methanol poisoning. The combines separation column micromachined chemoresistive gas sensor fully integrated into device that communicates wirelessly with smartphone. performance the is validated methanol-spiked 20 volunteers...
Introduction Over 800 people died this year in Iran alone as a result of methanol poisoning [1]. In fact, such outbreaks are quite common with thousands victims each [2]. However, no inexpensive and fast point-of-care method exists for diagnosis intoxication to rapidly respond disasters. Currently, is detected directly through blood analysis by gas chromatography or indirectly [3]. Both require trained personnel, expensive rarely available developing countries where most occur. Blood levels...
Introduction A major and largely underestimated [1] concern of today’s society is metabolic health (e.g. obesity) that related to several diseases (e.g., diabetes, cardiovascular illnesses). Various diet strategies ketogenic [2], intermittent fasting [3]) as well exercising are explored but the assessment treatment effectiveness on an individual level remains difficult. Desired simple accurate integrated devices communicate wirelessly [4] monitor changes conveniently at point-of-care. This...