A5037990948- Bone Tissue Engineering Materials
- Orthopaedic implants and arthroplasty
- Mesoporous Materials and Catalysis
- Dental Implant Techniques and Outcomes
- Microfluidic and Capillary Electrophoresis Applications
- Drug Solubulity and Delivery Systems
- Analytical Chemistry and Sensors
- Surfactants and Colloidal Systems
- 3D Printing in Biomedical Research
- Advanced Drug Delivery Systems
- Dental materials and restorations
- Advanced machining processes and optimization
- Surgical Sutures and Adhesives
- Electrostatics and Colloid Interactions
- Additive Manufacturing Materials and Processes
- Additive Manufacturing and 3D Printing Technologies
- Bone and Dental Protein Studies
- Zeolite Catalysis and Synthesis
- Conducting polymers and applications
- Periodontal Regeneration and Treatments
- Microfluidic and Bio-sensing Technologies
- Lipid Membrane Structure and Behavior
- Nanoparticle-Based Drug Delivery
- Magnesium Alloys: Properties and Applications
- Polyoxometalates: Synthesis and Applications
RISE Research Institutes of Sweden
2023
Sandvik (Sweden)
2011-2015
Uppsala University
2004-2009
Stockholm University
2007
Abstract We present here a study of the controlled release amino acid‐derived amphiphilic molecules from internal pore structure mesoporous nanoparticle drug delivery systems with different structural properties, namely cubic and hexagonal structures various degrees complexity. The surface nanomaterials presented has been functionalised amine moieties through one‐pot method. Release profiles obtained by conductivity measurements are interpreted in terms specific textural parameters porous...
Abstract Poor implant fixation and bone resorption are two of the major challenges in modern orthopedics caused by poor bone/implant integration. In this work, bioactive crystalline titanium dioxide (TiO 2 )/hydroxyapatite (HA) surfaces, functionalized with morphogenetic protein (BMP‐2), were evaluated as potential coatings for improved osseointegration. The outer layer consisted HA, which is known to be osteoconductive, may promote initial attachment when active molecules such BMP‐2 a...
We present here a detailed study of the controlled release amino acid derived amphiphilic molecules from internal pore structure mesoporous nanoparticle drug delivery systems with different structural properties; namely cubic and hexagonal structures various degrees complexity. The surface nanomaterials presented has been functionalised amine moieties through one pot method. Release profiles obtained by Alternating Ionic Current measurements are interpreted in terms specific textural...
The aim of this study is to show the potential using electrodynamic methods as characterization tools in controlled drug release process, on complex systems. two formulations under were a Carbopol gel containing diphenhydramine and an identical also surfactant sodium dodecyl sulfate which forms catanionic vesicles with diphenhydramine. average diffusion coefficients calculated from both dielectric spectroscopy transient current measurements. Comparing herein-obtained those obtained another...
This study was carried out to investigate the biological response in vivo biomimetic hydroxyapatite implant coatings functionalized with bisphosphonates and bone morphogenetic proteins. The functionalization by a simple soaking procedure operating room immediately prior surgery. Cylindrical titanium samples without were implanted distal femoral epiphysis of sheep retrieved after 6 weeks. histological analysis proved that all integrated well tissue no signs intolerance. Fewer osteoclasts...
Abstract Additive manufacturing (AM) using powder bed fusion is becoming a mature technology that offers great possibilities and design freedom for of near net shape components. However, many gas turbine aerospace applications, machining still required, which motivates further research on the machinability work piece integrity additive-manufactured superalloys. In this work, turning tests have been performed components made with both Powder Bed Fusion Laser Beam (PBF-LB) Electron (PBF-EB) in...
The purpose of this work is to study the kinetics self-assembly in formation mechanism anionic templated mesoporous solids (AMS-n) during first few seconds synthesis as well demonstrate use alternating ion current (AIC) conductivity measurements follow complex hybrid systems. different AMS-n caged-type mesostructures through delayed addition silica source demonstrated and explained terms interaction between co-structure-directing agent (CSDA) oppositely charged surfactant headgroup regions....
The aim of this study was to investigate if it is possible fast load hydroxyapatite with antibiotics and still obtain a slow but therapeutic release drugs during several hours. Physical vapour deposition used coat commercially pure titanium layer anatase TiO2. On top this, deposited using biomimetic precipitation. This coating then soaked in solutions containing for various amounts times. rate the measured PBS 22 released amount compared results from an antimicrobial susceptibility test...
A new method to investigate the effect of pore geometry on diffusion processes in mesoporous silica nanoparticles and other types micro- structures is put forward. The based study proton from a liquid surrounding particles into particle system. properties are assessed for variety as-synthesized nano- microparticles with two-dimensional three-dimensional connectivity. Results show that coefficients higher absorption process than release surfactant template molecules, they overall follow same...
Two methods of loading bisphosphonate (BP) into hydroxylapatite (HA) coatings on crystalline TiO2 surfaces were investigated to improve bone ingrowth implant surfaces. In the study BP pamidronate was used. Ti-plates coated with soaked in phosphate buffer saline (PBS) for 7 days at 40° C and thereafter solutions BP, 0.5 mg/ml 15 or 60 minutes (fast method). second method dissolved PBS different concentrations before immersion discs (co-precipitation Surface bulk analysed using electron...
We investigate the ion transport percolation properties of a binary system an conductor (NaCl) and insulator (ethyl cellulose) for which ac component conductivity is non-negligible over entire measured frequency range. find that dc conductivity, extracted from well-defined range frequencies, can be described by low threshold, ϕc=0.06 three-dimensional conducting network. The ϕc was explained water-layer-assisted conduction in micrometer-sized ethyl cellulose channels between NaCl grains....
Abstract Additive manufacturing (AM) using powder bed fusion is becoming a mature technology that offers great possibilities and design freedom for of near net shape components. However, many gas turbine aerospace applications machining still required, which motivates further research on the machinability work piece integrity additive manufactured superalloys. In this work, turning tests has been performed components made with both Powder Bed Fusion Laser Beam (PBF-LB) Electron (PBF-EB) in...