- Ophthalmology and Visual Impairment Studies
- Retinal Imaging and Analysis
- Intraocular Surgery and Lenses
- Glaucoma and retinal disorders
- Ophthalmology and Eye Disorders
- Retinal Diseases and Treatments
- Retinopathy of Prematurity Studies
- Ophthalmology and Visual Health Research
- Retinal and Macular Surgery
- Neonatal Respiratory Health Research
- Ocular Disorders and Treatments
- Neonatal Health and Biochemistry
- Vascular Malformations Diagnosis and Treatment
- Reconstructive Facial Surgery Techniques
- Visual perception and processing mechanisms
- Congenital Ear and Nasal Anomalies
- Retinal and Optic Conditions
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Receptor Mechanisms and Signaling
- Cerebral Venous Sinus Thrombosis
- Connexins and lens biology
- Genetic and Kidney Cyst Diseases
- Connective tissue disorders research
- Ocular Infections and Treatments
- Fetal and Pediatric Neurological Disorders
Queensland Children’s Hospital
2019-2024
The University of Queensland
2019-2023
Mater Mothers' Hospital
2023
Mater Misericordiae Hospital
2016
London School of Hygiene & Tropical Medicine
2006-2014
University of London
2008-2014
University of Auckland
2013-2014
Auckland District Health Board
2014
Medical Research Council
2010-2011
University College London
2010-2011
purpose. To determine the prevalence of blindness and visual impairment in adults aged 30 years older Pakistan to assess socio-demographic risk factors. methods. Multistage, stratified (rural/urban), cluster random sampling, with probability proportional-to-size procedures, was used select a nationally representative, cross-sectional sample age or older. Each subject interviewed; had acuity measured (logMAR; logarithm minimum angle resolution); underwent autorefraction, biometry,...
Anophthalmos, microphthalmos, and typical coloboma (AMC) form an interrelated spectrum of congenital eye anomalies that can cause significant visual loss cosmetic disfigurement in children. This prospective study children born the United Kingdom was undertaken to determine incidence AMC diagnosed by ophthalmologists explore sociodemographic risks.Recruitment achieved though established active surveillance system U.K. supported a new research network interested specialists, Surveillance Eye...
Purpose: To determine the prevalence of refractive error (RE) and spectacle wear to explore need for correction in adults (30 years or older) Pakistan. Methods: Multi-stage, cluster random sampling national survey. Each subject had their medical history taken, visual acuity measured, underwent autorefraction, biometry fundus examination. Those that presented with less than 6/12 either eye more detailed examination, including corrected distance measurement (autorefraction results placed a...
purpose. To determine the prevalence and causes of functional low vision (FLV) total blindness to estimate assessment needs for low-vision services in Pakistan. methods. Multistage, cluster random sampling was used select a nationally representative sample adults (age, ≥30 years). Participants underwent visual acuity measurement detailed ophthalmic examination. Functional defined as corrected better eye less than 6/18 more no perception light (NPL) individuals with untreatable loss. Total...
Purpose: To investigate the prevalence and risk factors for lens opacity (LO) amongst a nationally representative sample of adult population Pakistan. Methods: This national study blindness visual impairment (adults ≥30 years) used multistage, stratified, cluster random sampling. Grading LO was conducted using Mehra/Minassian classification system. LO, partly or wholly obscuring red reflex, previous cataract surgery were indicators opacity. Results: 16,402 (94.7%) adults included in this...
Purpose.: The goals of this study were to investigate the effectiveness computerized repeating and averaging visual acuity measurements in reducing test-retest variability (TRV) estimate increase sensitivity specificity that would be achieved diagnosing change. Methods.: Timed, paired ETDRS chart mean measurement (CAMM) performed 100 subjects. CAMM(n) scores running consecutive measurements. Bland-Altman methods used calculate 95% ranges for TRV. Results.: TRV range CAMM score after 6...
To compare the accuracy of retinopathy prematurity (ROP) screening between nurse specialists and an expert pediatric ophthalmologist.
Key Points TCRαβ+/CD19+-depleted haploidentical HSCT was used to restore immunity in a pediatric patient with combined immunodeficiency syndrome. Posttransplant drug-resistant CMV retinitis successfully treated T cells expanded from donor.
Children's vision screening children commonly uses optotype-based visual acuity or instrument-based methods measuring amblyogenic risk factors (ARFs).To compare the performance of Spot Vision Screener (SVS) (PediaVision, Welch Allyn, NY) and a nurse-administered screen (NVAS) in identifying ARFs decreased acuity.A prospective, cross-sectional population-based study preschool South-East Queensland, Australia. Eligible participants had both forms by trained community nurses. All with an...
Purpose: To assess visual functioning and quality of life in a representative sample normally sighted, visually impaired cataract operated individuals aged ≥ 30 years Pakistan. Methods: As part the Pakistan National Blindness Visual Impairment Survey, (VF) (QOL) questionnaires were administered to participants with presenting acuity less than 6/60 either eye, aphakes/pseudophakes phakic normal (≥ 6/12 both eyes). Results: Of 16,507 adults included survey, 2329 administered. There strong...
Identification and classification of all retinitis pigmentosa (RP) causing mutations contribute to a better understanding disease variants. In this report we describe New Zealand family, European heritage, affected by sectoral type RP phenotype in association with novel rhodopsin mutation (proline-170-histidine) highly conserved site.
Abstract Background Aim of this study was to evaluate the efficacy a novel algorithm customise overminus lens therapy in intermittent exotropia (IXT) based on clinical factors associated with control deviation. Methods Clinical parameters IXT vary among individuals. Based individual's physiological factors, an developed. Children aged between 4 and 15 years were randomised into OML observation groups. Participants group corrected for any significant refractive error. score, angle deviation,...
To estimate the outpatient clinic burden and surgical workload related to glaucoma in Lagos, Nigeria.A multicentre study involving 2 tertiary eye institutions, 7 secondary centers with care facilities, largest private hospital Lagos state, Nigeria. Data on department (OPD) visits were collected over a 4-week period, using specially designed tally sheet. Theater records examined each 1-year period (2009) for number types of surgeries performed.A total 6240 patients visited OPD out which 1577...
Purpose. Four weight-gain-based algorithms are compared for the prediction of type 1 ROP in an Australian cohort: weight, insulin-like growth factor, neonatal retinopathy prematurity (WINROP) algorithm, Children’s Hospital Philadelphia Retinopathy Prematurity (CHOPROP), Colorado (CO-ROP) and postnatal growth, (G-ROP) algorithm. Methods. A four-year retrospective cohort analysis infants screened a tertiary intensive care unit Brisbane, Australia. The main outcome measures were sensitivities,...
The aim of this report is to cover a novel presentation and subsequent management Purpureocillium (Paecilomyces) oculomycosis in child, review the available literature on endophthalmitis.This four year old boy from Australia. There have been 13 previous reports endophthalmitis, comprising 30 adult cases.AND IMPORTANCE. an emerging ocular infection, associated with use fungus as biological control agent. This case highlights importance early consideration intraocular fluid sampling vitritis...
Background Overminus lens is an effective non-surgical treatment of intermittent exotropia (IXT). Whether this causes development myopia recently debated. This study evaluated ocular biometric changes in IXT children treated with and without overminus lens. Methods Children were randomly assigned to control groups. Cycloplegic refraction, axial length other parameters (keratometry, anterior chamber depth thickness) for up 30 months compared between the Axial corneal curvature (AL/CR) ratio...
Amblyopic eyes typically exhibit greater lag of accommodation. Whether this improves after amblyopia treatment is inconclusive. The aim study to report post-treatment accommodative response in and investigate if the associated with visual acuity, duration, type.
To report the case of a young boy with early onset high myopia (eoHM), foveal hypoplasia and skeletal dysplasia due to homozygous
Retinopathy of prematurity (ROP) is a leading cause visual impairment in premature neonates. The BOOST II, SUPPORT and COT trials recommended increasing O2 saturation targets for pre-term neonates to reduce mortality; however, this risk factor ROP. We aimed determine whether these increased prevalence ROP among higher groups.Retrospective cohort study conducted using data from the Australian New Zealand Neonatal Network. 17 298 neonate born 2012-2018 at <32 weeks' GA and/or <1500 g BW was...
The clinical assessment of distance stereoacuity is important in some ocular conditions. Given the different neurophysiological mechanism for crossed and uncrossed stereoacuities, evaluation both may provide additional insight into binocular vision disorders.Clinical devices measuring stereopsis are not readily available. Visotec Distance Stereo Test (VDST) a contour-based device designed to measure forms stereoacuity. This study assesses validity test-retest reliability comparison random...