A5076569817- Medical and Biological Ozone Research
- Apelin-related biomedical research
- Hydrogen's biological and therapeutic effects
- Adipose Tissue and Metabolism
- Cardiovascular, Neuropeptides, and Oxidative Stress Research
- Adipokines, Inflammation, and Metabolic Diseases
- Cardiac Ischemia and Reperfusion
- Diet and metabolism studies
- Laser Applications in Dentistry and Medicine
- Acute Kidney Injury Research
- Paraoxonase enzyme and polymorphisms
- Hormonal Regulation and Hypertension
- Bioactive Compounds and Antitumor Agents
- Spaceflight effects on biology
- Dermatology and Skin Diseases
- Long-Term Effects of COVID-19
- COVID-19 Clinical Research Studies
- Acne and Rosacea Treatments and Effects
- Biochemical effects in animals
- Organ Transplantation Techniques and Outcomes
- Psoriasis: Treatment and Pathogenesis
- Plant-based Medicinal Research
- Hair Growth and Disorders
- Growth Hormone and Insulin-like Growth Factors
- Nuclear Receptors and Signaling
Kutahya Saglik Bilimleri Universitesi
2020-2025
Sağlık Bilimleri Üniversitesi
2022-2024
Universidad CES
2022-2024
University of Health Sciences Antigua
2022
Dumlupinar University
2013-2018
Sivas Cumhuriyet Üniversitesi
2018
Balıkesir University
2018
Erciyes University
2018
Pamukkale University
2010-2015
Denizli Devlet Hastanesi
2015
To examine the effects of adropin on glucose and lipid metabolism in a rat model Type 2 diabetes mellitus (T2DM).T2DM were established using high-fat diet streptozocin (STZ; 35 mg/kg/b.w.). Seven days after STZ induction, diabetic rats randomly treated with (2.1 μg/kg/day intraperitonealy) for 10 days. The study involved evaluation biochemical parameters, including blood glucose, total cholesterol (TC), triglycerides (TG), low-density lipoprotein-cholesterol (LDL-C), high-density (HDL-C),...
Ozone may promote moderate oxidative stress, which increases antioxidant endogenous systems. There are a number of antioxidants that have been investigated therapeutically for improving peripheral nerve regeneration. However, no previous studies reported the effect ozone therapy on facial regeneration.We aimed to evaluate regeneration.Fourteen Wistar albino rats were randomly divided into two groups with experimental crush injuries: control group, received saline treatment post-crush, and an...
Abstract Background Acne vulgaris is a multifactorial disease of the skin. Several studies have shown that elevated levels serum insulin‐like growth factor‐I (IGF‐I) correlate with overproduction sebum and acne. Recently functional relationship between IGF‐I (CA) polymorphism circulating in adults has been reported. Aims The aim our study was to investigate for first time whether might be involved pathogenesis acne or not. Methods We included 115 patients 117 healthy subjects study. clinical...
Apelin, a novel multifunctional peptide implicated in the regulation of cardiovascular system, including blood pressure and cardiac function control, has been postulated to be involved pathophysiology hypertension hypertensive heart disease. The aim this study was investigate, for first time, whether effects apelin's chronic application might deoxycorticosterone acetate-salt-induced rats (DOCA-salt rats). In study, 8–10-week-old male Wistar were divided into four groups: control + apelin,...
Renal ischemia-reperfusion (IR) injury is one of the most common causes acute kidney injury. This study investigated effects captopril (CAP), telmisartan (TEL) and bardoxolone methyl (BM) in animals with renal IR Adult male Wistar-Albino rats were divided into six groups: control, vehicle, IR, CAP, TEL BM. Before was induced, drugs administered by oral gavage. After a 60-min ischemia 120-min reperfusion period, bilateral nephrectomies performed. Serum urea, creatinine, neutrophil...
Background/Objectives: Acute coronary syndrome (ACS) is a critical cardiovascular condition influenced by genetic and environmental factors. Polymorphisms in methylenetetrahydrofolate reductase (MTHFR) deoxyribonucleic acid methyltransferase-1 (DNMT-1) genes are linked to diseases, yet their specific roles ACS pathogenesis remain unclear. This study examines the association of MTHFR C677T DNMT-1 +32204 A/G polymorphisms with potential contribution risk profiling. Methods: A case–control was...
Aim: To determine whether there is a correlation between cardiac markers and peri-operative myocardial injury (PMI) apoptosis in coronary artery bypass graft (CABG) surgery to compare the efficacy of detect PMI. Methods:The study population consisted 37 patients (24 male, 13 female, mean age 63.4 ± 8.9 years) undergoing elective CABG.Arterial sinus blood samples were collected just before aortic cross-clamping (pre-ACC) after declamping (post-ACC).Creatine kinase-MB isoenzyme (CK-MB)...
MicroRNAs (miR) are important diagnostic and treatment targets due to their different tissue expressions central position in the regulation of gene expressions. miR studies might pioneer emerging new tools goals kidney diseases. Captopril (CAP) telmisartan (TEL) were shown be effective ischemia reperfusion (IR) injury. There is not any study about effect TEL CAP over miR-21-320-146a. Our aim was effects on renal IR model.We used 12-16 weeks-old Wistar-Albino rats that weigh 300-350 g. Rats...
Background The aim of this study was to investigate the methylenetetrahydrofolate reductase (MTHFR) 677 C > T gene polymorphism in term infants born small (SGA), appropriate (AGA), and large for gestational age (LGA).
Apelin is a hypotensive peptide. Red blood cell (RBC) deformability and aggregation were previously demonstrated to be altered in various hypertension (HT) models. In the present study, we investigated possible alterations RBC response apelin DOCA-salt hypertensive rats. Rats randomly divided into 4 groups: Control (C), Hypertension (HT), Apelin, + (Apelin HT). HT was induced by injection of (25 mg/kg, s.c.) twice weekly for weeks, whereas administered (200 μg/kg i.p.) 17 days. determined...
Tumor necrosis factor-alpha (TNF-α) is a protein that plays key role in the pathophysiology of chronic inflammatory disorders like psoriasis.The goal this study was to see whether TNF-α gene -238G>A polymorphism linked psoriasis susceptibility.This comprised 90 patients and ninety healthy controls. For polymorphism, genomic DNA extracted genotyped using polymerase chain reaction (PCR) restriction fragment length (RFLP) studies.Psoriasis had higher frequencies A allele AA genotype than...