Yuanyuan Zhang

ORCID: 0000-0003-4734-4356
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About
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Research Areas
  • Distributed Control Multi-Agent Systems
  • Distributed and Parallel Computing Systems
  • Adaptive Control of Nonlinear Systems
  • Parallel Computing and Optimization Techniques
  • Neural Networks Stability and Synchronization
  • Birth, Development, and Health
  • Obesity, Physical Activity, Diet
  • CAR-T cell therapy research
  • Space Satellite Systems and Control
  • Cloud Computing and Resource Management
  • Advanced Data Storage Technologies
  • Extracellular vesicles in disease
  • Biochemical Analysis and Sensing Techniques
  • Maternal Mental Health During Pregnancy and Postpartum
  • Dye analysis and toxicity
  • Lymphoma Diagnosis and Treatment
  • Hearing, Cochlea, Tinnitus, Genetics
  • Mathematical and Theoretical Epidemiology and Ecology Models
  • RNA Interference and Gene Delivery
  • Stability and Control of Uncertain Systems
  • Olfactory and Sensory Function Studies
  • Ion Channels and Receptors
  • Dynamics and Control of Mechanical Systems
  • Advanced Chemical Sensor Technologies
  • Breastfeeding Practices and Influences

Liaocheng People's Hospital
2025

Huzhou University
2025

Dana-Farber Cancer Institute
2025

Huazhong University of Science and Technology
2015-2024

Tongji Hospital
2020-2024

Zhengzhou University of Light Industry
2024

Gansu University of Traditional Chinese Medicine
2024

Shandong Institute of Automation
2023

Union Hospital
2015-2017

Wuhan National Laboratory for Optoelectronics
2016

Gliomas are incurable malignancies notable for having an immunosuppressive microenvironment with abundant myeloid cells, the immunomodulatory phenotypes of which remain poorly defined1. Here we systematically investigate these by integrating single-cell RNA sequencing, chromatin accessibility, spatial transcriptomics and glioma organoid explant systems. We discovered four expression programs: microglial inflammatory scavenger programs, both unique to primary brain tumours, systemic...

10.1038/s41586-025-08633-8 article EN cc-by-nc-nd Nature 2025-02-26

Oxidative stress is reported to regulate several apoptotic and necrotic cell death pathways in auditory tissues. Poly(ADP-ribose) polymerase-1 (PARP-1) can be activated under oxidative stress, which the hallmark of parthanatos. Autophagy, serves either a pro-survival or pro-death function, also stimulated by but role autophagy its relationship with parthanatos underlying this activation inner ear remains unknown. In study, we established an model vitro glucose oxidase/glucose (GO/G), could...

10.1016/j.redox.2017.10.002 article EN cc-by-nc-nd Redox Biology 2017-10-12

With the increasing popularity of mobile phones, potential hazards radiofrequency electromagnetic radiation (RF-EMR) on auditory system remain unclear. Apart from RF-EMR, humans are also exposed to various physical and chemical factors. We established a lipopolysaccharide (LPS)-induced inflammation in vitro model investigate whether possible sensitivity spiral ganglion neurons damage caused by phone (at specific absorption rates: 2, 4 W/kg) will increase. Spiral (SGN) were obtained neonatal...

10.1186/s12974-015-0300-1 article EN cc-by Journal of Neuroinflammation 2015-05-28

The ability to accurately predict future resource capabilities is of great importance for applications and scheduling algorithms which need determine how use time-shared resources in a dynamic grid environment. In this paper we present evaluate new innovative method the one-stepahead CPU load grid. Our prediction strategy forecasts based on tendency several past steps previous similar patterns, uses polynomial fitting method. experimental results demonstrate that achieves average errors are...

10.1109/ccgrid.2006.27 article EN 2006-01-01

This research investigated the growth, serum biochemistry, antioxidant capability, and immunity impact of black carp fed degossypolled cottonseed protein replacing fishmeal at levels 0%, 10%, 20%, 30%, 40%, 50% (DCP0, DCP10, DCP20, DCP30, DCP40, DCP50), respectively. The results showed there were no significant changes in growth among these test groups. activities mRNA expression amylase trypsin heightened conjunction with 30-40% DCP. Although insulin contents reduced a rise DCP content,...

10.3390/ani15101404 article EN cc-by Animals 2025-05-13

This article designs an effective consensus control protocol for continuous-time second-order time-delayed multiagent systems in a multiplicative noisy environment, using absolute velocity and relative position measurements. The nonlinear case double-integrator are studied, respectively. Due to the time delay noise such models, conventional methods analysis not applicable. In this article, therefore, degenerated Lyapunov functional is used derive conditions mean-square almost-sure consensus,...

10.1109/tcyb.2019.2954623 article EN IEEE Transactions on Cybernetics 2019-12-10

Background: Stomach adenocarcinoma (STAD) is one of the most common tumors. Tumor mutation burden (TMB) has been linked to immunotherapy response. We wanted see if there was any link between TMB and cancer prognosis. Methods: The Cancer Genome Atlas (TCGA) Gene Expression Omnibus (GEO) databases were used obtain data, gene expression profiles, clinical data. looked at differences in immune markers low high groups, built an prognostic model, created a dynamic nomograph App that may be clinic....

10.3389/fcell.2022.790920 article EN cc-by Frontiers in Cell and Developmental Biology 2022-03-23

Abstract Background The clinical characteristics and prognosis of primary intestinal diffuse large B‐cell lymphoma (PI‐DLBCL) are rarely reported. We aimed to explore the role surgery in patients with PI‐DLBCL. Methods Adult PI‐DLBCL were included from Surveillance, Epidemiology, End Results database. effect was evaluated by Kaplan–Meier Cox proportional regression analyses. Propensity score matching (PSM) used reinforce our results. Lasso utilized determine independent risk factors overall...

10.1002/cam4.3882 article EN cc-by Cancer Medicine 2021-05-01

Oxidative damage to the inner ear is responsible for several types of sensorineural deafness. Cochlear stria marginal cells (MCs) are thought be vulnerable such oxidative stress. Activated poly(ADP-ribose) polymerase 1 (PARP1) has been implicated in diseases, but effect PARP1 on MCs subjected stress remains elusive. In this study, we established an vitro cellular model using glucose oxidase (GO) and attempted explore role that plays MCs. poly-ADP-ribose (PAR) were highly expressed GO-treated...

10.1007/s12035-015-9469-7 article EN cc-by Molecular Neurobiology 2015-11-02
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