Karin Nielsen

ORCID: 0000-0003-4736-8980
Publications
Citations
Views
---
Saved
---
About
Contact & Profiles
Research Areas
  • Radiopharmaceutical Chemistry and Applications
  • Medical Imaging Techniques and Applications
  • Orthopedic Infections and Treatments
  • HIV/AIDS Research and Interventions
  • Hepatocellular Carcinoma Treatment and Prognosis
  • HIV Research and Treatment
  • Infective Endocarditis Diagnosis and Management
  • Nuclear Physics and Applications
  • Gastrointestinal disorders and treatments
  • Adolescent Sexual and Reproductive Health
  • HIV, Drug Use, Sexual Risk
  • DNA Repair Mechanisms
  • Medical Imaging and Pathology Studies
  • Mosquito-borne diseases and control
  • HIV-related health complications and treatments
  • Hernia repair and management
  • Radiation Therapy and Dosimetry
  • COVID-19 epidemiological studies
  • Advanced biosensing and bioanalysis techniques
  • COVID-19 Clinical Research Studies
  • HIV/AIDS drug development and treatment
  • Colorectal Cancer Treatments and Studies
  • Sugarcane Cultivation and Processing
  • Intraperitoneal and Appendiceal Malignancies
  • Body Contouring and Surgery

King's College London
2021-2024

St Thomas' Hospital
2022-2024

University of California, Los Angeles
1996-2023

Vrije Universiteit Amsterdam
2013-2021

Amsterdam University Medical Centers
2018-2021

Aalborg University Hospital
2013-2020

University of Copenhagen
2013-2020

Technical University of Denmark
2019-2020

Noordwest Ziekenhuisgroep
2019

Copenhagen University Hospital
2018

Radiofrequency ablation (RFA) and microwave (MWA) are widely accepted techniques to eliminate small unresectable colorectal liver metastases (CRLM). Although previous studies labelled thermal inferior surgical resection, the apparent selection bias when comparing patients with disease candidates, superior safety profile, competitive overall survival results for more recent reports mandate setup of a randomized controlled trial. The objective COLLISION trial is prove non-inferiority compared...

10.1186/s12885-018-4716-8 article EN cc-by BMC Cancer 2018-08-15

Pre-exposure prophylaxis (PrEP), condom use, post-exposure (PEP), and sexual partner reduction help to prevent HIV acquisition but have low uptake among young people. We aimed assess the efficacy of automated text messaging monitoring, online peer support, strengths-based telehealth coaching improve adherence PrEP, PEP adolescents aged 12-24 years at risk in Los Angeles, CA, USA, New Orleans, LA, USA.

10.1016/s2589-7500(23)00252-2 article EN cc-by The Lancet Digital Health 2024-02-21

Background Irreversible electroporation (IRE), an ablative technique that uses high-voltage electrical pulses, has shown promise for eradicating tumors near critical structures, including blood vessels and bile ducts. Purpose To investigate the efficacy safety of IRE colorectal liver metastases (CRLMs) unsuitable resection or thermal ablation because proximity to structures further systemically administered treatments. Materials Methods Between June 2014 November 2018, participants with...

10.1148/radiol.2021203089 article EN Radiology 2021-03-16

Despite promising anti-cancer properties in vitro, all titanium-based pharmaceuticals have failed vivo. Likewise, no target-specific positron emission tomography (PET) tracer based on the radionuclide 45Ti has been developed, notwithstanding its excellent PET imaging properties. In this contribution, we present liquid–liquid extraction (LLE) flow-based recovery and purification of 45Ti, computer-aided design, synthesis a salan-natTi/45Ti-chelidamic acid (CA)-prostate-specific membrane...

10.3390/molecules25051104 article EN cc-by Molecules 2020-03-02

The presence of human immunodeficiency virus (HIV) in cervicovaginal secretions (CVS) may be a risk factor for perinatal transmission. CVS 25 women were evaluated HIV and mucosal antibodies; 16 infants had gastric aspirates cultured. Maternal plasma was measured by quantitative RNA polymerase chain reaction. Seven (28%), 4 19 pregnant 3 7 nonpregnant, CVS. Two HIV-infected neonates positive aspirate cultures. with did not transmit infection. HIV-specific secretory IgA present 10 (42%) 24 (in...

10.1093/infdis/173.4.1001 article EN The Journal of Infectious Diseases 1996-04-01

In patients that require treatment for hepatic giant cavernous hemangiomas (GCH), radiofrequency ablation (RFA) has been suggested to represent a safe and effective alternative invasive surgery. recent report of bipolar RFA, using two expandable needle electrodes, was uneventfully performed in with large GCH (>10 cm). The objective this is present cases which RFA symptomatic complicated by acute kidney injury. 2015 we treated very (15.7 25.0 cm) during open laparotomy. both the urine showed...

10.1007/s00270-016-1415-1 article EN cc-by CardioVascular and Interventional Radiology 2016-07-07

Thermal ablation of colorectal liver metastases (CRLM) may result in local progression, which generally appear within a year treatment. As the timely diagnosis this progression allows potentially curative treatment, an optimal follow-up imaging strategy is essential. PET-MRI one potential modality, combining advantages PET and MRI. The aim study evaluate fluorine-18 deoxyglucose positron emission tomography (FDG) as modality for detection tumor during first following thermal ablation,...

10.1186/1471-2342-14-27 article EN cc-by BMC Medical Imaging 2014-08-08

Formulae display:?Mathematical formulae have been encoded as MathML and are displayed in this HTML version using MathJax order to improve their display. Uncheck the box turn off. This feature requires Javascript. Click on a formula zoom.

10.1080/07366299.2019.1646982 article EN cc-by-nc-nd Solvent Extraction and Ion Exchange 2019-07-29

Objective. To identify the population of human immunodeficiency virus–infected pediatric long- term survivors (LTS) followed in major medical institutions California, Florida and New Jersey. Methods. A cross-sectional survey was performed with data collection forms sent to all investigators. Demographic, clinical, laboratory were obtained on living patients ≥8 years infected perinatal period virus. Results. total 143 perinatally 54 children by neonatal transfusion identified. Fifty-four...

10.1542/peds.99.4.e4 article EN PEDIATRICS 1997-04-01

The imaging of infectious and inflammatory diseases using gallium-67 (67Ga) citrate scintigraphy has been a well-established diagnostic tool for decades. In recent times, interest focused on PET the short-lived positron emitting radioisotope 68Ga. 68Ga is not only more readily available, it also provides better quality images whose high resolution permits quantitative analyses, thus improving management patients suffering from infections or inflammation. purpose our study was to develop fast...

10.1097/mnm.0b013e328363142f article EN Nuclear Medicine Communications 2013-06-13

Purpose The aim of this study was to evaluate the clinical safety profile 68Ga-PSMA-11 ligand for PET/CT imaging in prospective trials. Methods Eighty-eight patients with newly diagnosed or recurrent prostate cancer participated 2 Safety reporting identical administered as MBq/kg body weight (mean, 9.2 μg, 9.7 nmol). adverse events (AEs) and measurement blood pressure (BP) heart rate (HR) were performed prior injection (baseline); immediately after (postinjection); at 1, 10, 60 minutes...

10.1097/rlu.0000000000001681 article EN Clinical Nuclear Medicine 2017-05-06

Manganese porphyrins have several therapeutic/imaging applications, including their use as radioprotectants (in clinical trials) and paramagnetic MRI contrast agents. The affinity of for lipid bilayers also makes them candidates cell/liposome labelling. We hypothesised that metalation with the positron emission tomography (PET) radionuclide

10.1016/j.nucmedbio.2022.08.006 article EN cc-by Nuclear Medicine and Biology 2022-09-02

A technic is described for the study of mast cells on such “natural tissue spreads” as external periosteum calvarium and dura mater small laboratory rodents. These membranes can be fixed flat sheets, while still attached to their normal osseous base, without use customary traumatic procedures incident preparation artificial mounts.

10.3181/00379727-112-28077 article EN Experimental Biology and Medicine 1963-02-01

The development of bacteria-specific infection radiotracers is considerable interest to improve diagnostic accuracy and enabling therapy monitoring. aim this study was determine if the previously reported radiolabelled 1,4,7,10-tetraazacyclododecane-N,N',N″,N‴-tetraacetic acid (DOTA) conjugated peptide [

10.1002/jlcr.3640 article EN Journal of Labelled Compounds and Radiopharmaceuticals 2018-05-23

Abstract Background Tenofovir disoproxil fumarate (TDF) in combination with other antiretroviral (ARV) drugs has been clinical use for HIV treatment since its approval 2001. Although the effectiveness of TDF preventing perinatal infection is well established, information about renal safety during pregnancy still limited. Trial design The IMPAACT PROMISE study was an open-label, strategy trial that randomized pregnant women to one three arms: based therapy (ART), zidovudine (ZDV) ART, and ZDV...

10.1186/s12879-022-07608-8 article EN cc-by BMC Infectious Diseases 2022-07-20
Coming Soon ...