A5083387348- Analytical Chemistry and Chromatography
- Analytical Methods in Pharmaceuticals
- Pharmacological Effects and Assays
- Antibiotics Pharmacokinetics and Efficacy
- Antimicrobial agents and applications
- Cardiac Valve Diseases and Treatments
- Mycotoxins in Agriculture and Food
- Biopolymer Synthesis and Applications
- Pharmacogenetics and Drug Metabolism
- Molecular Sensors and Ion Detection
- Environmental Chemistry and Analysis
- Pharmacological Receptor Mechanisms and Effects
- Advanced Photocatalysis Techniques
- Cardiac, Anesthesia and Surgical Outcomes
- Pharmaceutical and Antibiotic Environmental Impacts
- Analytical Chemistry and Sensors
- biodegradable polymer synthesis and properties
- Antimicrobial Peptides and Activities
- Cardiac and Coronary Surgery Techniques
- Advanced Chemical Sensor Technologies
- Synthesis of Indole Derivatives
- Biocrusts and Microbial Ecology
- Sesame and Sesamin Research
- Medicinal plant effects and applications
- Neuroscience and Neuropharmacology Research
Medical University of Silesia
2015-2024
Jagiellonian University
2012-2022
Silesian Center for Heart Disease
2018
Instytut Przemysłu Skórzanego
2017
Łukasiewicz Research Network - Institute for Engineering of Polymer Materials and Dyes
2011
Institute of Agricultural and Food Biotechnology
2005-2006
The purpose of this work was to study two methods degradation roxithromycin: acidic hydrolysis and photocatalytic under illumination with near-UV light in the presence TiO<sub>2</sub>photosensitizer.
A routine method appropriate for the determination of ochratoxin (OTA) in wine, grape juice and drinks was described, occurrence mycotoxin investigated most popular red wines, available on Polish market. After clean-up immunoaffinity column, samples were analysed by RP-HPLC using a fluorescence detector at 330 460 nm. The average OTA recoveries from spiked blank wine varied 60 to 82%, RSD% ranged 5 14%. recovery 80-100%, but between 7 10%. limit detection quantitation all sample types 0.5...
The pharmacokinetic profile and tissue uptake of daidzein (DAI) was determined in rat serum tissues (lungs, eyes, brain, heart, spleen, fat, liver, kidney, testes) after intravenous intraperitoneal administration DAI suspension or complexed with ethylenediamine-modified γ-cyclodextrin (GCD-EDA/DAI). absolute relative bioavailability suspended (20 mg/kg i.v. vs. 50 i.p.) (0.54 1.35 determined. After i.p. administration, absorption GCD-EDA more rapid (tmax = 15 min) than that 45 a ca. 3.6...
A thin-layer chromatographic/densitometric method was developed for the identification and quantitation of oxytetracycline, tiamulin, lincomycin, spectinomycin in veterinary preparations. Silica gel-coated thin layer chromatography plates 2 mobile phases were used to separate these constituents. The appropriate compositions suitable established: 10% citric acid solution-n-hexane-ethanol (80 + 1 1, v/v) n-butanol-ethanol-chloroform-25% ammonia (4 5 5, v/v). Along with Rf values spot colors,...
ENWEndNote BIBJabRef, Mendeley RISPapers, Reference Manager, RefWorks, Zotero AMA Kaczmarczyk M, Szałański P, Zembala et al. CARDIAC SURGERYMinimally invasive aortic valve replacement – pros and cons of keyhole surgery. Kardiochirurgia i Torakochirurgia Polska/Polish Journal Thoracic Cardiovascular Surgery. 2015;12(2):103-110. doi:10.5114/kitp.2015.52850. APA Kaczmarczyk, M., Szałański, P., Zembala, Filipiak, K., Karolak, W., & Wojarski, J. (2015). Surgery, 12(2), 103-110....
A hybrid adsorbent/photocatalyst was obtained and used for the removal of microcystin-LR, a potent toxin, from water via adsorption photocatalyzed oxidation with singlet oxygen. The combined adsorption/photooxidation processes yielded 500-fold decrease overall MC-LR concentration. can be easily removed reaction system by sedimentation or centrifugation.
A simple, selective, and sensitive thin-layer chromatographic—densitometric method has been developed for the determination of sulfasalazine besides its possible impurities in pharmaceutical preparations. The mobile phase was composed ethyl acetate—methanol—ammonia 25% 10:7:3 (υ/υ/υ), stationary aluminum plates precoated with silica gel 60 F254 that enabled to obtain well resolved peaks impurities. chromatograms were analyzed densitometrically at λ = 360 nm. RF values ultraviolet (UV)...
The main objective of this research was to investigate the relationship between polarity atenolol, acebutolol, and propranolol described by logP kinetic thermodynamic parameters characterizing their degradation process in acidic solution. Hydrolysis carried out hydrochloric acid at molal concentrations 0.1 mol/L, 0.5 1 mol/L for 2 hr 40 degrees C, 60 90 C. Chromatographic-densitometric method used determination drugs under investigation. identification products using 1H NMR. processes that...
The purpose of this work was to develop a sensitive stability-indicating TLC-densitometric method for determination azithromycin (AZ) in the presence its impurities E, I, and L, study stability AZ under different stress conditions. developed on TLC aluminum plates precoated with silica gel F254 using mobile phase methanol-acetone-ammonia 25% (2+13+0.1, v/v/v), which gives compact zones (Rf= 0.39) L (Rf = 0.54, 0.20, 0.05, respectively). Densitometric analysis carried out at 483 nm after...
Abstract A thin‐layer chromatography (TLC)‐densitometric method has been developed for the identification and quantification of fusidic acid (FA) (RF=0.53), methyl hydroxybenzoate (MHB) (RF=0.64), propyl (PHB) (RF=0.72), butylated hydroxyanisol (BHA) (RF=0.77), which are components a dermatological ointment. To separate these constituents, n‐hexane‐ethyl acetate‐glacial acetic (6∶3∶1, v/v/v) used as mobile phase silica gel 60 F254 TLC plates stationary phase. detect spots on chromatograms,...
Abstract Applicability of derivative spectrophotometry for the determination valsartan in presence a substance from group statins was checked. The obtained results indicate that proposed method may be effective by using appropriate derivatives: and fluvastatin - D1, D2 D3, pravastatin D1 atorvastatin D3. characterized high sensitivity accuracy. Linearity maintained following ranges: 9.28-32.48 mg mL -1 valsartan, 8.16-28.56 f or fluvastatin, 14.40-39.90 9.60-48.00 pravastatin. Determination...
The purpose of this work was to develop a TLC-densitometric method for simultaneous identification and quantitative determination azithromycin, clarithromycin, roxithromycin, spiramycin, troleandomycin. developed on TLC aluminium plates precoated with silica gel F254 using solvent system izopropanol:n-hexane:ammonia 25% (8:12:3, v/v/v), which gives compact spots azithromycin (RF = 0.65), clarithromycin 0.54), roxithromycin 0.49), spiramycin 0.22), troleandomycin 0.36). Densitometric analysis...