A5083706094- Peripheral Artery Disease Management
- Prostate Cancer Diagnosis and Treatment
- Cardiac, Anesthesia and Surgical Outcomes
- Aortic aneurysm repair treatments
- Cerebrovascular and Carotid Artery Diseases
- Reconstructive Surgery and Microvascular Techniques
- Diabetic Foot Ulcer Assessment and Management
- Vascular Procedures and Complications
- Urinary Bladder and Prostate Research
- Acute Ischemic Stroke Management
- Mitochondrial Function and Pathology
- Genetic Neurodegenerative Diseases
- Health Systems, Economic Evaluations, Quality of Life
- Hospital Admissions and Outcomes
- Functional Brain Connectivity Studies
- Innovations in Medical Education
- Prostate Cancer Treatment and Research
- Advanced Neuroimaging Techniques and Applications
- Statistical Methods and Bayesian Inference
- Bladder and Urothelial Cancer Treatments
- Urological Disorders and Treatments
- Neurological disorders and treatments
- Organ and Tissue Transplantation Research
- Renal cell carcinoma treatment
- Statistical Methods and Inference
Brigham and Women's Faulkner Hospital
2011-2018
Harvard University
2006-2018
Brigham and Women's Hospital
2009-2018
Medtronic (United States)
2015-2017
Saint Thomas Health
2015
Henry Ford Health System
2015
University of Minnesota
2015
Dana-Farber Cancer Institute
2008-2015
University of Massachusetts Chan Medical School
2011-2014
University of Pittsburgh Medical Center
2014
Background— The majority of infrarenal abdominal aortic aneurysm (AAA) repairs in the United States are performed with endovascular methods. Baseline aortoiliac arterial anatomic characteristics fundamental criteria for appropriate patient selection repair (EVAR) and key determinants long-term success. We evaluated compliance guidelines EVAR relationship between baseline anatomy post-EVAR AAA sac enlargement. Methods Results— Patients pre-EVAR at least 1 computed tomography scan were...
The clinical phenotype of Huntington's disease (HD) is far more complex and variable than depictions it as a progressive movement disorder dominated by neostriatal pathology represent. availability novel neuro-imaging methods has enabled us to evaluate cerebral cortical changes in HD, which we have found occur early be topographically selective. What less clear, however, how these influence the expression disease. In this study, used high-resolution surface based analysis vivo MRI data...
Humans exhibit significant interindividual variability in behavioral reaction time (RT) performance yet the underlying neural mechanisms for this remain largely unknown. It has been proposed that RT may be due to differences white matter (WM) physiological properties, although such a relationship never demonstrated cortical projection or association pathways healthy young adults. Using diffusion tensor MRI (DTI), we sought test whether fractional anisotropy (FA), measure of orientational...
Abstract Atrophy of cortical and subcortical gray matter is apparent in Huntington's disease (HD) before symptoms manifest. We hypothesized that the white (WM) connecting regions must also be affected early select clinical were related to systems degeneration. used diffusion tensor magnetic resonance imaging (DTI) examine regional nature WM abnormalities HD, including preclinical period, determine whether changes correlated with features. studied individuals stages (HD), presymptomatic known...
No AccessJournal of UrologyAdult Urology1 Apr 2012Use, Costs and Comparative Effectiveness Robotic Assisted, Laparoscopic Open Urological Surgery Hua-yin Yu, Nathanael D. Hevelone, Stuart R. Lipsitz, Keith J. Kowalczyk, Jim C. Hu YuHua-yin Yu Division Urology, Brigham Women's/Faulkner Hospital, Harvard Medical School, Boston, Massachusetts , HeveloneNathanael Hevelone Center for Public Health, LipsitzStuart Lipsitz KowalczykKeith Kowalczyk HuJim View All Author...
To design an evidence-based intervention to address physician distress, based on the attitudes toward support among physicians at our hospital.
The authors studied presymptomatic individuals with the Huntington disease (HD) mutation to determine whether cortical thinning was present. They found that regionally selective, semi-independent of striatal volume loss, and correlated cognitive performance. Early, extensive involvement occurs during preclinical stages HD.
In a randomized, double-blind, placebo-controlled study in 64 subjects with Huntington disease (HD), 8 g/day of creatine administered for 16 weeks was well tolerated and safe. Serum brain concentrations increased the creatine-treated group returned to baseline after washout. 8-hydroxy-2′-deoxyguanosine (8OH2′dG) levels, an indicator oxidative injury DNA, were markedly elevated HD reduced by treatment.
Background— Vein bypass surgery is an effective therapy for atherosclerotic occlusive disease in the coronary and peripheral circulations; however, long-term results are limited by progressive attrition of graft patency. Failure vein grafts patients with critical limb ischemia morbidity, loss, additional resource use. Although technical factors known to be success surgical revascularization, patient-specific risk not well defined. In particular, relationship race/ethnicity gender outcomes...
Failure to rescue (FTR), the mortality rate among surgical patients with complications, is an emerging quality indicator. Hospitals a high safety-net burden, defined as proportion of covered by Medicaid or uninsured, provide disproportionate share medical care vulnerable populations. Given financial strains on hospitals availability clinical resources may have role in outcome disparities.To assess association between burden and FTR evaluate effect this relationship.A retrospective cohort...
<h3>Objective</h3> Acute limb ischemia remains one of the most challenging emergencies in vascular surgery. Historically, outcomes following interventions for acute have been associated with high rates morbidity and mortality. The purpose this study was to determine contemporary lower extremity bypass performed ischemia. <h3>Methods</h3> All patients undergoing infrainguinal between 2003 2011 within hospitals comprising Vascular Study Group New England were identified. Patients stratified...