Sandrine Lavau‐Denès
A5084236822- Cancer survivorship and care
- Nutrition and Health in Aging
- Cancer Treatment and Pharmacology
- Breast Cancer Treatment Studies
- Colorectal Cancer Treatments and Studies
- Lung Cancer Treatments and Mutations
- Central Venous Catheters and Hemodialysis
- Venous Thromboembolism Diagnosis and Management
- HER2/EGFR in Cancer Research
- Gastric Cancer Management and Outcomes
- Childhood Cancer Survivors' Quality of Life
- Head and Neck Cancer Studies
- Frailty in Older Adults
- Chemotherapy-related skin toxicity
- Advanced Breast Cancer Therapies
- Gastrointestinal disorders and treatments
- Monoclonal and Polyclonal Antibodies Research
- Multiple and Secondary Primary Cancers
- Oral health in cancer treatment
- Gastrointestinal Tumor Research and Treatment
- Pharmaceutical Practices and Patient Outcomes
- Hepatocellular Carcinoma Treatment and Prognosis
- Genetic factors in colorectal cancer
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Peptidase Inhibition and Analysis
Université de Limoges
2009-2022
John Wiley & Sons (United States)
2021
Hudson Institute
2021
Centre Hospitalier Universitaire de Limoges
2013-2021
Charles River Laboratories (Netherlands)
2021
Hôpital Dupuytren
2001-2020
Hôpital Universitaire Dupuytren
2012-2020
Centre de Recherche en Cancérologie de Toulouse
2018
Clinique Pasteur
2018
Institut Bergonié
2018
Objective We tested the effect of dietary advice dedicated to increase intake in older patients at risk for malnutrition during chemotherapy, versus usual care, on one-year mortality. Method conducted a multicentre, open-label interventional, stratified (centre), parallel randomised controlled trial, with 1∶1 ratio, two-year follow-up. Patients were aged 70 years or treated chemotherapy solid tumour and (MNA, Mini Nutritional Assessment 17–23.5). Intervention consisted diet counselling aim...
BackgroundMetastatic colorectal cancer frequently occurs in elderly patients. Bevacizumab combination with front line chemotherapy (CT) is a standard treatment but some concern raised about tolerance of bevacizumab for these The purpose PRODIGE 20 was to evaluate and efficacy according specific end points this population.Patients methodsPatients aged 75 years over were randomly assigned + CT (BEV) versus CT. LV5FU2, FOLFOX FOLFIRI regimen prescribed investigator's choice. composite...
Small bowel adenocarcinoma (SBA) is a rare tumour. We conducted prospective cohort to describe the prevalence, survival and prognostic factors in unselected SBA patients. The study enrolled patients with all stages of newly diagnosed or recurrent at 74 French centres between January 2009 December 2012. In total, 347 were analysed; median age was 63 years (range 23-90). primary tumour duodenum (60.6%), jejunum (20.7%) ileum (18.7%). prevalence predisposing disease 8.7%, 6.9%, 1.7%, 1.7% 0.6%...
Abstract Background Older adults with cancer experience negative long‐term functional effects of both and treatments. Exercise may minimize their age‐related cancer‐related decline. Methods We conducted a multicentre open‐label 12 month randomized clinical trial two parallel arms including participants aged ≥70 years lymphoma or carcinoma requiring curative treatment. The study started at the beginning any phase treatment (surgery, chemotherapy, radiotherapy). usual care group (UCG) received...
BACKGROUND Treatment strategies for locally advanced breast cancer in elderly patients too frail to receive neoadjuvant chemotherapy and the introduction of new classes drugs early 2000s have led consideration endocrine therapy as a treatment younger hormone receptor (HR)–positive, postmenopausal not eligible primary breast‐conserving surgery (BCS). METHODS This was multicenter, phase 2, randomized trial designed evaluate its objective clinical response rate after up 6 months (NET) alone...
Objectives: Physical activity (PA) programs are recommended for breast cancer care. However, their modalities remain to be discussed. This study determined the best time begin a personalized or adapted program based on cardiopulmonary exercise test function. randomized controlled trial evaluated effect of home-based PA (APA) performed during after treatment cardiorespiratory fitness (CRF) at 12 months. Method: The primary endpoint was peak oxygen consumption (VO 2peak ) months (group A vs C...
Abstract Small bowel adenocarcinoma (SBA) is a rare tumour. Large genomic analyses with prognostic assessments are lacking. The NADEGE cohort has enrolled 347 patients all stage SBA from 2009 to 2012. Next‐generation sequencing investigates the presence of 740 hotspot somatic mutations in panel 46 genes involved carcinogenesis. mismatch repair (MMR) status was assessed by immunochemistry. We have collected 196 tumour samples and 125 had conclusive results for mutation analysis. number 0 9.6%...
// David G. Cox 1 , Elsa Curtit 2 Gilles Romieu 3 Pierre Fumoleau 4 Maria Rios 5 Hervé Bonnefoi 6 Thomas Bachelot 7 Patrick Soulié 8 Christelle Jouannaud 9 Hugues Bourgeois 10 Thierry Petit 11 Isabelle Tennevet 12 Assouline 13 Marie-Christine Mathieu 14 Jean-Philippe Jacquin 15 Sandrine Lavau-Denes 16 Ariane Darut-Jouve 17 Jean-Marc Ferrero 18 Carole Tarpin 19 Lévy 20 Valérie Delecroix 21 Véronique Trillet-Lenoir 22 Oana Cojocarasu 23 Jérôme Meunier 24 Jean-Yves Pierga 25 Céline...
BackgroundA surveillance program was performed in colorectal cancer (CRC) patients after surgery, to diagnose asymptomatic recurrence.AimsTo assess whether 18-FDG positron emission tomography/CT (PET/CT) improved the detection of recurrence during a 3-year follow-up.MethodsA multicentre, two-arm randomised prospective trial comparing different 36-month follow-up strategies. Complete colonoscopy at baseline and 3 years clinical exams with imaging every months. The conventional arm (A)...