A5028103366- Pluripotent Stem Cells Research
- CRISPR and Genetic Engineering
- Cardiomyopathy and Myosin Studies
- Neuroscience and Neural Engineering
- Cardiac electrophysiology and arrhythmias
- RNA Research and Splicing
- Ion channel regulation and function
- Viral Infections and Immunology Research
- Cardiovascular Function and Risk Factors
- Congenital heart defects research
- Cardiovascular Effects of Exercise
Allen Institute for Cell Science
2024
British Columbia Children's Hospital
2021-2022
Simon Fraser University
2018-2022
The epithelial to mesenchymal transition (EMT) is a widely studied but poorly defined state change due the variety of ways in which it has been characterized cells. There need for reproducible cell model systems that enable integration and comparison different types measured observations cells across many distinct cellular contexts. We present human induced pluripotent stem (hiPS) as such system by demonstrating its utility through comparative analysis hiPS cell-EMT 2D 3D culture geometries....
Hypertrophic cardiomyopathy (HCM) is one of the most common heritable cardiovascular diseases and variants