A5051559063- Cancer Immunotherapy and Biomarkers
- Lung Cancer Diagnosis and Treatment
- Lung Cancer Research Studies
- Lung Cancer Treatments and Mutations
- Advanced Radiotherapy Techniques
- Prostate Cancer Diagnosis and Treatment
- Prostate Cancer Treatment and Research
- Cancer Genomics and Diagnostics
- CAR-T cell therapy research
- Colorectal Cancer Surgical Treatments
- Colorectal and Anal Carcinomas
- Medical Imaging Techniques and Applications
- Immunotherapy and Immune Responses
- Oral health in cancer treatment
- Assisted Reproductive Technology and Twin Pregnancy
- Radiomics and Machine Learning in Medical Imaging
- Glioma Diagnosis and Treatment
- Cancer, Lipids, and Metabolism
- Pancreatic and Hepatic Oncology Research
- Biomedical Research and Pathophysiology
- Cancer Diagnosis and Treatment
- Abdominal Trauma and Injuries
- Renal cell carcinoma treatment
- Angiogenesis and VEGF in Cancer
- COVID-19 and healthcare impacts
Instituto de Investigación Biomédica de Málaga
2021-2024
Universidad de Málaga
2021-2024
Hospital Clínico Universitario Virgen de la Victoria
2021-2024
Hospital Universitario de Gran Canaria Doctor Negrín
2019-2022
Up to 80% of patients under immune checkpoint inhibitors (ICI) face resistance. In this context, stereotactic ablative radiotherapy (SABR) can induce an or abscopal response. However, its molecular determinants remain unknown. We present early results a translational study assessing biomarkers response combined ICI and SABR (I-SABR) in liquid biopsy from oligoprogressive prospective observational multicenter study. Cohort A includes metastatic oligoprogression maintaining the same due...
Introduction: The standard therapy for locally advanced rectal cancer (LARC) is based on neoadjuvant chemoradiotherapy (nCRT) with fluoropyrimidines. There are different biomarkers used as prognostic factors in these tumors. Some studies advocate the use of neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte (PLR) this clinical scenario. aim study was to evaluate NLR PLR disease-free survival (DFS) overall (OS) predictive pathologic complete response (pCR) using Ryan tumor...
The present study aimed to investigate the potential of basal cell-free fluorometric DNA (cfDNA) quantification as a prognostic biomarker in advanced non-small cell lung cancer (NSCLC) patients treated with an Immune Checkpoint Blockade (ICB). A discovery and validation cohort 61 31 ICB were included this study. Quantification cfDNA concentration was performed before start treatment followed up for median 34 (30-40) months. predicted value evaluated based on ROC, Cox regression conducted via...
Hydatid disease usually affects the liver, but can also extend to other locations, such as bones. In these cases, complete resection of bone is considered only curative approach. However, this rarely feasible, and patients are left with benzimidazoles their option. context, there an evident need for alternative treatments that improve results. We present case a patient treatment-refractory hydatid cyst bone, who successfully underwent radiotherapy (RT).A 64-year-old woman was diagnosed in...
8537 Background: Tobacco is the main risk factor for developing lung cancer. Yet, some heavy smokers do not develop cancer while others at young ages. The study of immunology has led to surge immune checkpoint blockade (ICB), which transformed treatment landscape pts. NQO1 been associated with extreme phenotypes high development tobacco-induced NSCLC and poor survival outcomes xerographs. Development biomarkers ICB mainly focused on tumor-related factors genetic susceptibility host poorly...
Radical prostatectomy (RP) is one of the primary treatment options for localised prostate cancer (PCa). Despite its curative intent, 1/3 patients will experience biochemical recurrence (BCR) during follow-up. Experts have devoted efforts to associate influence each individual factor with risk BCR select optimal patient. Optimal management must aim find a balance between delaying onset metastatic disease and overtreating an indolent treatments that can affect quality life patients. Thus far,...
Patients with rectal cancer may develop gastrointestinal toxicity associated chemo-radiotherapeutic treatment that conditions their clinical, functional, and nutritional evolution. The aim of the study was to evaluate efficacy supplementation a glutamine-enriched peptide diet (PD) compared exclusive dietary advice (DA) on toxicity, interruption oncologic treatment, evolution in patients undergoing neoadjuvant treatment.