- Bee Products Chemical Analysis
- Skin Protection and Aging
- Antioxidant Activity and Oxidative Stress
- Cell death mechanisms and regulation
- Immune cells in cancer
- Bioactive Natural Diterpenoids Research
- Plant Toxicity and Pharmacological Properties
- Heat shock proteins research
- Autophagy in Disease and Therapy
- MicroRNA in disease regulation
- Genetics, Aging, and Longevity in Model Organisms
- Sesquiterpenes and Asteraceae Studies
- Healthcare and Venom Research
- Organ Transplantation Techniques and Outcomes
The Affiliated Yongchuan Hospital of Chongqing Medical University
2022-2024
Chongqing Medical University
2022-2024
Hangzhou Medical College
2024
Guangdong Medical College
2023
Chinese herbs have been used to treat small-cell lung cancer (SCLC) due their low toxicity and significant efficacy. This study focused on oridonin, a natural compound extracted from Rabdosia rubescens, aimed investigate its potential antitumor activity SCLC evaluate the synergistic effect of combining oridonin with other small molecules. In this study, exhibited dual effect. At lower concentrations, it suppressed cell viability cells (H1688 H446). high induced apoptosis, damaged HBE in...
Ultraviolet (UV) irradiation has been well documented to be linked with almost all skin problems we know, and both dermis epidermis may affected varying degrees by UV irradiation. Every time when exposed sunlight without protection, our will step closer photoaging, leading irreversible consequences ultimately. Heat shock protein 27 (HSP27) is a vital involved in cell growth, autophagy, apoptosis, drug resistance, tumor genesis metastasis. Evidence suggests that the organism subjected various...
Abstract Continuous exposure to UVB is the main extrinsic cause of skin photodamage, which associated with oxidative stress, DNA damage, apoptosis and degradation collagen. Rapamycin, a mechanistic target inhibitor rapamycin complex 1 (mTORC1), has been shown play crucial role anti-tumor aging retardation, but its mechanism action in UVB-induced photodamage still remains unknown. In this study, we investigated Hspb2(also known as Hsp27)in mice. Histological results showed that knockout hspb2...
Hepatoprotective effects of the mixed decoction Inula cappa and Serissa japonica in acute liver injury mouse model