A5031833600- Forensic and Genetic Research
- Indigenous Cultures and History
- Economic Theory and Policy
- Pediatric Hepatobiliary Diseases and Treatments
- Market Dynamics and Volatility
- Intestinal Malrotation and Obstruction Disorders
- Genomics and Phylogenetic Studies
- Risk and Portfolio Optimization
- COVID-19 epidemiological studies
- Banking stability, regulation, efficiency
- Demographic Trends and Gender Preferences
- Congenital Heart Disease Studies
- Immune Response and Inflammation
- interferon and immune responses
- RNA regulation and disease
- Genetic diversity and population structure
- Politics and Society in Latin America
- RNA and protein synthesis mechanisms
- Global Health Care Issues
- Race, Genetics, and Society
- Credit Risk and Financial Regulations
Universidad de la República de Uruguay
2016-2022
Institut Pasteur
2016
Systems approaches for the study of immune signaling pathways have been traditionally based on purified cells or cultured lines. However, in vivo responses involve coordinated action multiple cell types, which interact to establish an inflammatory microenvironment. We employed standardized whole-blood stimulation systems test hypothesis that Toll-like receptor ligands whole microbes can be defined by transcriptional signatures key cytokines. found 44 genes, identified using Support Vector...
The Amerindian group known as the Charrúas inhabited Uruguay at timing of European colonial contact. Even though they were extinguished an ethnic a result genocide, Charrúan heritage is part Uruguayan identity both culturally and genetically. While mitochondrial DNA studies have shown evidence ancestry in living Uruguayans, here we undertake whole-genome sequencing 10 individuals with self-declared Charruan heritage. We detect chromosomal segments supporting presence indigenous genetic...
Abstract The Amerindian group known as the Charrúas inhabited Uruguay at timing of European colonial contact. Even though they were extinguished an ethnic a result genocide, Charrúan heritage is part Uruguayan identity both culturally and genetically. While mitochondrial DNA studies have shown evidence ancestry in living Uruguayans, here we undertake whole-genome sequencing 10 individuals with Charruan heritage. We detect chromosomal segments supporting presence indigenous genetic...
<p style='text-indent:20px;'>Statistical dependence between the GDP growth projection adjustments for end of 2020 and health impact Covid-19 pandemic is detected quantified a broad set countries. A <inline-formula><tex-math id="M1">\begin{document}$\texttt{rate }$\end{document}</tex-math></inline-formula> that captures this each country contrasted to difference in projections released two subsequent times: 2019 (pre-pandemic) early (post-pandemic). The variables...
This paper deals with credit risk in the Uruguayan aggregate economy and therefore correspond to financial stability purposes. To analyze associ- ated a portfolio of loans nonlinear parametric model based on Merton’s approach is used, which default event occurs if returns economic agent falls below certain threshold that depends macroeconomic variables. The estimated models can help understand relationship between indicators. results obtained be considered for estimating module stress tests...
The ancestry of each locus the genome can be estimated (local ancestry) based on sequencing or genotyping information together with reference panels ancestral source populations. length those ancestry-specific genomic segments are commonly used to understand migration waves and admixture events. In short time scales, it is often interest determine existence most recent unadmixed ancestor from a specific population t generations ago. We built hypothesis test if an individual has belonging...