A5085691703- Natural product bioactivities and synthesis
- Phytochemistry and Biological Activities
- Phytochemicals and Antioxidant Activities
- Fungal Biology and Applications
- Urinary Tract Infections Management
- Plant Toxicity and Pharmacological Properties
- Cassava research and cyanide
- Phytochemical Studies and Bioactivities
- Essential Oils and Antimicrobial Activity
- Saffron Plant Research Studies
- Polysaccharides and Plant Cell Walls
- Nephrotoxicity and Medicinal Plants
- Microbial Natural Products and Biosynthesis
- Sesquiterpenes and Asteraceae Studies
- Ethnobotanical and Medicinal Plants Studies
- Fermentation and Sensory Analysis
- Traditional Chinese Medicine Analysis
- Natural Antidiabetic Agents Studies
- Escherichia coli research studies
- Metabolomics and Mass Spectrometry Studies
- Botanical Studies and Applications
- Phytochemistry and Bioactive Compounds
- Chemical synthesis and alkaloids
- Kidney Stones and Urolithiasis Treatments
- Herbal Medicine Research Studies
University of Münster
2016-2025
Cairo University
2019
Shahid Beheshti University
2010
Sharif University of Technology
2010
Heinrich Heine University Düsseldorf
2009-2010
National University of Mongolia
2009
Helmholtz Centre for Infection Research
2009
Ocean University of China
2009
University of Strathclyde
2009
Six new chromones, named pestalotiopsones A−F (1−6), and the known derivative 7-hydroxy-2-(2-hydroxypropyl)-5-methylchromone (7) were obtained from mycelia culture filtrate of mangrove endophytic fungus Pestalotiopsis sp., which was isolated leaves Chinese Mangrove plant Rhizophora mucronata. Their structures elucidated on basis spectroscopic data. Pestalotiopsones are chromones having both an alkyl side chain substituted at C-2 a free or carboxyl group C-5. Compound 6 exhibited moderate...
Combretum mucronatum Schumach. & Thonn. is a medicinal plant widely used in West African traditional medicine for wound healing and the treatment of helminth infections. The present study aimed at phytochemical characterization hydroalcoholic leaf extract this identification anthelmintic compounds by bioassay-guided fractionation. An EtOH-H2O (1:1) from defatted leaves was partitioned between EtOAc H2O. Further fractionation performed fast centrifugal partition chromatography,...
Abstract LC-MS characterized cranberry extract from the fruits of Vaccinium macrocarpon inhibited under in vitro conditions bacterial adhesion Escherichia coli strain 2980 uropathogenic E. (UPEC strains UTI89, NU14) to T24 bladder cells and UPEC CFT073 A498 kidney a concentration-dependent manner. Within biomedical study, urine samples 16 volunteers (8 male, 8 female) consuming for 7 d (900 mg/d) were analyzed potential antiadhesive activity against by ex vivo experiments. Results indicated...
A new sesterterpene (1), a norsesterterpene (3), and two norditerpenes (4, 5) were isolated from the aerial parts of Salvia sahendica, together with 12 known compounds, comprising sesterterpene, sesquiterpene, diterpene, triterpenes, steroidal five flavonoids. The structures compounds established by spectroscopic data interpretation, in case 4, its structure was confirmed single-crystal X-ray analysis.
Peptidoglycan is the basic structural polymer of bacterial cell wall and maintains shape integrity single cells. Despite years research conducted on peptidoglycan’s chemical composition, microscopic elucidation its nanoscopic architecture still needs to be addressed more thoroughly advance knowledge physiology. Apart from model organism Escherichia coli, ultrastructural imaging data murein Gram-negative bacteria mostly missing today. This study therefore intended further our understanding...
For the treatment of urinary tract infections mixtures different herbal materials are frequently used within traditional clinical practice. A complex formulation, widely in Germany for preparation aqueous extracts, with Betula sp., Agropyron repens, Solidago gigantea, and Ononis spinosa was infused as a mixture from all four components (combined extract). In addition, herbs were extracted separately extracts mixed subsequently (separate None influenced proliferation UPEC-UTI89 cell viability...
The identification of antiviral natural products as new lead structures has become a major task in medical science. Especially saponins have gained high interest for their activity. Antiviral effects the saponin-containing plant Anagallis arvensis, widely used traditional medicine, been described, while mode action or detailed phytochemical and functional investigations are still missing. A saponin enriched extract (AAS) from aerial material A. arvensis was characterized detail by LC-HRMS,...
Naphthoquinones (NQs) occur naturally in a large variety of plants. Several NQs are highly active against protozoans, amongst them the causative pathogens neglected tropical diseases such as human African trypanosomiasis (sleeping sickness), Chagas disease and leishmaniasis. Prominent NQ-producing plants can be found among Juglans spp. (Juglandaceae) with juglone derivatives known constituents. In this study, 36 variable extracts were prepared from different plant parts J. regia, cinerea...
Chromatographic separation of a crude extract obtained from aerial parts the Mongolian medicinal plant Scorzonera radiata yielded five new dihydrostilbenes, scorzodihydrostilbenes A−E (1−5). The structures were unambiguously elucidated on basis one- and two-dimensional NMR (1H, 13C, COSY, HMBC, HMQC, ROESY) mass spectrometric data. Compounds 1−5 exhibited antioxidative activity when analyzed in DPPH (2,2-diphenyl-1-picrylhydrazyl) assay. For 1 5 antioxidant activities stronger than that...