A5034889522- Head and Neck Surgical Oncology
- Cancer Diagnosis and Treatment
- Cancer, Stress, Anesthesia, and Immune Response
- Head and Neck Anomalies
- Ear Surgery and Otitis Media
- Head and Neck Cancer Studies
- Pituitary Gland Disorders and Treatments
- Nicotinic Acetylcholine Receptors Study
- Cancer Immunotherapy and Biomarkers
- CAR-T cell therapy research
- Cholinesterase and Neurodegenerative Diseases
- Cutaneous Melanoma Detection and Management
- Tumors and Oncological Cases
- Psoriasis: Treatment and Pathogenesis
- Immunotherapy and Immune Responses
- Neuroendocrine Tumor Research Advances
- Congenital Ear and Nasal Anomalies
- Trauma Management and Diagnosis
- Epilepsy research and treatment
- Cancer Genomics and Diagnostics
- Ear and Head Tumors
- Pharmacological Effects and Toxicity Studies
- Salivary Gland Tumors Diagnosis and Treatment
- Cerebrospinal fluid and hydrocephalus
- Sinusitis and nasal conditions
The University of Texas MD Anderson Cancer Center
2021-2024
Baylor College of Medicine
2020-2024
Management of oral cavity squamous cell carcinoma (OSCC) involves a multidisciplinary team approach. Surgery is ideally the primary treatment option for nonmetastatic OSCC, and less invasive curative surgical approaches are preferred in early-stage disease to minimize surgical-related morbidity. For patients at high risk recurrence, adjuvant using radiation therapy or chemoradiation often used. Systemic may also be used neoadjuvant setting (for advanced-stage with intent mandibular...
The incidence of human papilloma virus–mediated oropharyngeal squamous cell carcinoma (OPSCC) has increased over the past 40 years, particularly among young individuals with a favorable prognosis; however, current therapy often leads to unfortunate side effects, such as dysphagia. Despite emphasis on dysphagia in previous studies, there is an important research gap understanding correlation between neuronal changes and patient-reported functional outcomes patients OPSCC. To address this...
Objective: To discuss persistent facial nerve stimulation (FNS) related to repeated electrostatic discharge (ESD) shock following cochlear implantation. Methods: Single case report with literature review. Results: FNS is a feared complication after implantation, occurring in approximately 7% of cases, most patients having anatomic abnormalities. The presented has no anatomical abnormalities but reported frequent environmental static shock. during the first 1 3 seconds processor attachment...
Abstract Objective The neurocognitive associations in paediatric obstructive sleep apnoea (OSA) are well known; however, whether polysomnographic features can predict these is unknown. Therefore, the primary objective of this study was to compare common parameters children with OSA presence and absence dysfunction. Methods Polysomnography data for ages 3‐6 years mild‐moderate who as defined by AHI between 5 10 were analysed from a single centre at tertiary hospital January 2016 December...
Esthesioneuroblastoma (ENB) is a rare neuroendocrine malignancy of the olfactory epithelium that infrequently presents with syndrome inappropriate antidiuretic hormone (SIADH). We discuss case 37-year-old woman history primary hypothyroidism and systemic lupus erythematosus (SLE) presenting SIADH prior to diagnosis left nasal cavity ENB (Kadish stage B, Hyams grade 1). Her was obfuscated by concomitant discovery pituitary microadenoma, hypothyroidism, adrenal insufficiency due longstanding...
Abstract Nonmelanoma skin cancer is the most common malignancy and immunosuppression a key risk factor. Despite promising data demonstrating efficacy of immune checkpoint inhibition in treatment cutaneous squamous cell carcinoma (cSCC), immunosuppressed patients are not included immunotherapy trials due to for toxicity lack regarding cSCC landscape patients. To characterize specific alterations accounting diminished antitumor response patients, we used multispectral imaging on pathology...
Abstract Immunosuppression is a major risk and prognostic factor for cutaneous squamous cell carcinoma (cSCC). Immune checkpoint inhibition approved the treatment of cSCC, yet most immunosuppressed patients are ineligible immunotherapy. Better understanding on tumor microenvironment cSCC in context immunosuppression (i.e., organ transplant recipients, with hematological malignancies or autoimmune diseases acquired immunodeficiencies such as HIV) utmost importance proper implementation...
Abstract Despite the excellent prognosis of patients with oropharyngeal squamous cell carcinoma (OPSCC), long-term functional impairment (e.g., dysphagia) is a major burden for many patients. Recent studies have explored role pharyngeal constrictors and muscle fibrosis in dysphagia. However, to date, no study has examined association between OPSCC neural microenvironment posttreatment impairment. We hypothesized that cancer-related neuronal changes tumor (TME) would affect patients’...
Esthesioneuroblastoma (ENB) is a rare neuroendocrine malignancy of the olfactory epithelium that lines superior nasal cavity may uncommonly present with syndrome inappropriate antidiuretic hormone (SIADH). We case 37-year-old woman history primary hypothyroidism and systemic lupus erythematosus (SLE) presenting SIADH 2.5 years prior to diagnosis left ENB (Kadish's stage B, Hyams' grade 1) who experienced resolution her hyponatremia over 24 hours following transnasal endoscopic resection...