Sobia Rafiq

ORCID: 0000-0003-4821-5783
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About
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Research Areas
  • Colorectal Cancer Screening and Detection
  • Genetic factors in colorectal cancer
  • Colorectal and Anal Carcinomas
  • Cancer, Lipids, and Metabolism
  • Lipoproteins and Cardiovascular Health
  • Gastric Cancer Management and Outcomes
  • Bioinformatics and Genomic Networks
  • Innovation and Socioeconomic Development
  • Cerebrovascular and Carotid Artery Diseases
  • Genetics, Aging, and Longevity in Model Organisms
  • Genetic Associations and Epidemiology
  • Microbial Metabolic Engineering and Bioproduction
  • vaccines and immunoinformatics approaches
  • Gene expression and cancer classification
  • Immunotherapy and Immune Responses
  • Monoclonal and Polyclonal Antibodies Research
  • CRISPR and Genetic Engineering
  • Inflammatory Biomarkers in Disease Prognosis
  • Cardiovascular Health and Disease Prevention
  • Biological Research and Disease Studies

Khyber Medical University
2023-2024

Ajou University
2024

Aga Khan University Hospital
2013-2014

University of Karachi
2012

Background. Early onset colorectal carcinoma (CRC) is rare and has been hypothesized to be a biologically clinically distinct entity personifying aggressive disease worse survival. Methods. Data for 131 patients was collected by retrospective chart review. Cox proportional hazard model used compute prevalence ratios 95% confidence intervals. Results. sporadic CRC accounted 32% of all treated in the specified time period. The mean age 33.3 ± 7.9 years male female ratio 2 : 1. Colon rectal...

10.1155/2014/461570 article EN ISRN Oncology 2014-04-01

e14680 Background: Early onset colorectal carcinoma (CRC), defined as CRC at age below 45 years is rare. However, an increasing incidence has been noted in Southeast Asia. It hypothesized to be a biologically and clinically distinct entity personifying aggressive disease worse survival. Data on this subject scarce from part of the world hence our objective was study clinical presentation outcome early sporadic patients single tertiary care center Pakistan. Methods: collected by retrospective...

10.1200/jco.2013.31.15_suppl.e14680 article EN Journal of Clinical Oncology 2013-05-20

Despite the advancements in cancer treatment and benefits of personalized medicine, breast (BC) remains a significant health concern. Moreover, conventional options are costly often associated with severe side effects, highlighting need to identify new biomarkers innovative strategies for BC. Drug repurposing presents an approach that expands therapeutic window further mitigate financial burden minimize potential harm caused by existing anticancer drugs. In present study, we aim suggest...

10.55627/pmc.003.01.0300 article EN cc-by Precision Medicine Communications 2023-06-30

Abstract Background There are various treatment options for breast cancer, but a delayed diagnosis at an advanced stage negatively affects overall survival. Our objective is to investigate the prognostic significance of modified Glasgow Prognostic Score (mGPS) with different modalities. Materials and methods The study was longitudinal cohort conducted in Biochemistry laboratory Institute Basic Medical Sciences Khyber University. Enrolling 121 patients invasive carcinoma from November 2018...

10.1007/s44337-024-00123-6 article EN cc-by Deleted Journal 2024-11-14
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