- SARS-CoV-2 and COVID-19 Research
- Animal Virus Infections Studies
- Viral gastroenteritis research and epidemiology
- Glaucoma and retinal disorders
- Retinal Development and Disorders
- Natural Language Processing Techniques
- Speech Recognition and Synthesis
- SARS-CoV-2 detection and testing
- Retinal Diseases and Treatments
- Acute Ischemic Stroke Management
- Neuroscience and Neuropharmacology Research
- Liquid Crystal Research Advancements
- Cardiac Ischemia and Reperfusion
- Graphene and Nanomaterials Applications
- Advanced Fiber Optic Sensors
- Innovative Human-Technology Interaction
- Ubiquitin and proteasome pathways
- Nanoparticles: synthesis and applications
- COVID-19 epidemiological studies
- vaccines and immunoinformatics approaches
- Topic Modeling
- Corneal surgery and disorders
- Network Security and Intrusion Detection
- Molecular spectroscopy and chirality
- Viral Infections and Immunology Research
Saitama Red Cross Hospital
2025
Institute of Molecular Biology, Academia Sinica
2024
Chung Yuan Christian University
2015-2024
Beijing University of Technology
2024
China Medical University
2023-2024
First Hospital of China Medical University
2023
Taipei City Government
2023
Bridge University
2023
Purdue University West Lafayette
2009-2022
National Taiwan University
2013-2022
The discovery of novel antiviral materials is important because many infectious diseases are caused by viruses. Silver nanoparticles have demonstrated strong activity, and graphene a potential antimicrobial material due to its large surface area, high carrier mobility, biocompatibility. No studies on the activity nanomaterials non-enveloped viruses been reported. To investigate oxide (GO) sheets GO with silver particles (GO-Ag) against enveloped viruses, feline coronavirus (FCoV) an envelope...
Purpose To determine the long-term intraocular pressure (IOP) control and postoperative complications after initial trabeculectomy with use of mitomycin C (MMC) in patients primary open-angle glaucoma (POAG). Patients Methods A retrospective review was conducted a consecutive series 123 eyes (87 patients) POAG who underwent MMC had at least 4 years follow-up. All standard 0.04% applied intraoperatively for 3 minutes. The outcomes (IOP bleb leak, long-standing hypotony, bleb-related...
We conducted a post hoc exploratory analysis of Remote Ischemic Conditioning for Acute Moderate Stroke (RICAMIS) to determine whether early remote ischemic conditioning (RIC) initiation after stroke onset was associated with clinical outcome in patients acute moderate stroke.In RICAMIS, receiving RIC treatment the intention-to-treat were divided into 2 groups based on onset-to-treatment time (OTT): group (OTT ≤ 24 hours) and late 24-48 hours). Patients usual care without from assigned as...
This retrospective study compares the surgical outcomes of ab interno trabeculotomy using Kahook Dual Blade (KDB) and Tanito microhook (TMH) combined with cataract surgery. Twenty-four eyes from 19 17 patients glaucoma in KDB TMH groups, respectively, were included. Background factors matched for medication score disease type propensity scores. Preoperative age, sex, intraocular pressure (IOP), scores, comparable between groups. The intraoperative incision range was lower than group....
A simple chemical method was developed for preparing high valence silver (Ag)-loaded mesoporous silica (Ag-ethylenediaminetetraacetic acid (EDTA)-SBA-15), which showed strong antibacterial activity. Ag-EDTA-SBA-15 exhibited stronger and more effective activity than commercial Ag nanoparticles did, it offered stability of in the porous matrix long-lasting The synthesized materials were characterized using Fourier transform infrared spectroscopy, powder X-ray diffraction (XRD), photoelectron...
This paper presents the use of a magnetic manipulation device to remotely control movement Ag/Fe3O4 nanoparticles (NPs) for enhancing antibacterial effect Ag particles in aqueous suspensions containing Escherichia coli (E. coli). The NPs were prepared by co-precipitation method where are simultaneously synthesized with Fe3O4 form and nanocomposite materials. system utilized homogeneous rotating field carry out stirring petri dishes bacterial suspensions. optimum magnetron parameters best...
A transgenic papaya line (TPY10-4) that is resistant to both ringspot virus (PRSV) and leaf distortion mosaic (PLDMV) has been developed in Taiwan. This study investigated the immunomodulatory properties of TPY10-4 its native (TCK) fruits using an ovalbumin (OVA)-sensitised mouse model. Both green ripe at low (0.2 g powder kg(-1) body weight (BW)) high (1.6 BW) doses were administered experimental mice by intragastric gavage for 5 weeks. Changes serum total immunoglobulin (IgA), IgE, IgG IgM...
Little is known about the neutralizing epitopes in turkey coronavirus (TCoV). The spike (S) protein gene of TCoV was divided into 10 fragments to identify antigenic region containing epitopes. expression and antigenicity S confirmed by immunofluorescence antibody (IFA) assay using an anti-histidine monoclonal or anti-TCoV serum. Polyclonal antibodies raised against expressed S1 (amino acid position 1 573 from start codon protein), 4F/4R (482-678), 6F/6R (830-1071), Mod4F/Epi4R (476-520)...
Bats are natural reservoirs of severe acute respiratory syndrome coronavirus (SARS-CoV) and Middle East CoV (MERS-CoV). Scotophilus bat CoV-512 demonstrates potential for cross-species transmission because its viral RNA specific antibodies have been detected in three species Taiwan. Understanding the cell tropism is first step studying mechanism transmission. In this study, a lentivirus-based pseudovirus was produced using spike (S) protein or SARS-CoV as surface to test interaction between...
The available tooth whitening products in the market contain high concentrations of hydrogen peroxide (H2O2) as an active ingredient. Therefore, order to curb H2O2 concentration and instability liquid H2O2, this study evaluated efficacy cytotoxicity bleaching gel composed 10% calcium (CaO2) visible-light-activating nitrogen-doped titanium dioxide (N-TiO2) with methyl cellulose a thickener. Extracted bovine teeth were discolored using coffee black tea stain solution divided into two groups (n...
Remote ischemic conditioning has been found to be effective in improving functional outcomes acute stroke. We conducted a post hoc analysis of the RICAMIS (Remote Ischemic Conditioning for Acute Moderate Stroke) trial determine whether long-term remote duration after stroke onset is associated with better clinical
Qingfeng Sun, Can Xu, Huang Hu, Yujing Wang, Jian Miao, Xiubo Geng, Yining Chen, Fei Daxin Jiang. Proceedings of the 2022 Conference North American Chapter Association for Computational Linguistics: Human Language Technologies. 2022.
Turkey coronavirus (TCoV) causes acute atrophic enteritis and uneven flock growth in turkey farms leading to economic loss. Since 1990's, flocks have kept experiencing coronaviral sporadically the United States, Canada, Europe, Brazil. Poult mortality syndrome (PEMS) caused by co-infection of TCoV, astrovirus, other viruses or bacteria resulted significantly high mortality. Diagnosis TCoV depends on reverse transcription polymerase chain reaction (RT-PCR), quantitative real-time PCR,...