A5032202397- Laser Applications in Dentistry and Medicine
- Laser Material Processing Techniques
- Bone and Dental Protein Studies
- Bone Tissue Engineering Materials
- Dental materials and restorations
- Effects of Radiation Exposure
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Dental Implant Techniques and Outcomes
- Bone health and osteoporosis research
- Radiation Therapy and Dosimetry
- DNA Repair Mechanisms
- Orthopedic Infections and Treatments
- Cancer, Hypoxia, and Metabolism
- Hippo pathway signaling and YAP/TAZ
- Pharmacological Effects of Natural Compounds
- Bone health and treatments
- Hemoglobin structure and function
- Radiation Dose and Imaging
- Ultrasound and Hyperthermia Applications
- Peptidase Inhibition and Analysis
- Cancer, Stress, Anesthesia, and Immune Response
- Orthodontics and Dentofacial Orthopedics
- Cell death mechanisms and regulation
- Cancer Cells and Metastasis
- Cardiac Fibrosis and Remodeling
Biologie, ingénierie et imagerie pour l'Ophtalmologie
2022-2025
Université de Bretagne Occidentale
2025
SAnté INgenierie BIOlogie Saint-Etienne
2021-2024
Université Jean Monnet
2021-2024
Inserm
2011-2024
Mines Saint-Étienne
2023
Université Claude Bernard Lyon 1
2022
Institut Mérieux (France)
2012
Centre de Recherche en Cancérologie de Lyon
2011
Centre National d'Études Spatiales
2011
Ultrashort pulse lasers have significant advantages over conventional continuous wave and long for the texturing of metallic surfaces, especially nanoscale surface structure patterning. Furthermore, ultrafast laser beam polarization allows precise control spatial alignment nanotextures imprinted on titanium-based implant surfaces. In this article, we report biological effect human mesenchymal stem cell differentiation. We created, polished titanium-6aluminum-4vanadium (Ti-6Al-4V) plates, a...
ABSTRACT Background The critical importance of effective oxygen delivery during organ preservation to prevent ischemia–reperfusion injury has been reported in the literature. Moreover, traditional methods often fail meet oxygenation needs, prompting research into alternatives like hemoglobin‐based carriers (HBOCs) such as M101 provided by HEMARINA. This extracellular hemoglobin, derived from Arenicola marina , shows a high affinity for and delivers it through physiological gradient under...
Unrepaired and misrepaired DNA Double-Strand Breaks (DSBs) were shown to be the key events of radiation-induced toxicity (radiosensitivity) genomic instability (cancer proneness), respectively. We have previously that immunofluorescence with γ -H2AX MRE11 biomarkers may account for unrepaired DSBs doses higher than 1 Gy. Three radiosensitivity groups had been defined (group I: radioresistance; group II: moderate cancer proneness; III: hyper-radiosensitivity). Here, we investigated X-ray...
Abstract Dental implant failure is primarily due to peri-implantitis, a consequence of bacterial biofilm formation. Bacterial adhesion strongly linked micro-/nano-topographies surface; thus an assessment surface texture parameters essential understand adhesion. In this study, mirror polished titanium samples (Ti6Al4V) were irradiated with femtosecond laser (fs-L) at wavelength 1030 nm (infrared) variable (laser beam polarization, number, spacing and organization the impacts). Images 3-D...
Abstract Titanium alloys are widely used in bio-medical applications for their excellent bio-compatibility and superior mechanical strength. On the other hand, femtosecond laser processing is a robust versatile industrial method surface functionalization. In this work, laser-induced periodic structures (LIPSS) on titanium alloy (Ti6Al4V) using different wavelengths of 1030 nm (IR), 515 (Green) 257 (UV) were created wettability (physical parameter correlated with cell adhesion) was studied,...
Abstract Objectives MTX is the recommended first-line treatment for RA associated with folic acid (FA) to reduce side effects related MTX. Here, we proposed test a co-administration of FA in rat adjuvant-induced arthritis (AIA) on efficacy. Material and methods AIA was induced female Lewis rats treated three groups. The first group received only (n = 13), whereas second same day 14). third one after Arthritic index (AI), ankle circumference (AC), microcomputed tomography, blood tests...
<h3>Background</h3> Rheumatoid arthritis (RA) is the most common chronic inflammatory rheumatic disease, characterized by synovitis associated with progressive bone loss and joint swelling. The adjuvant-induced (AIA) model mimics pathophysiological features of RA, a very high prevalence reproducibility. YAP plays key role in synovial hyperplasia. It transcription factor which can be activated response to inflammation but also mechanical stimulus as tissue stiffening. We already showed...
The adjuvant-induced arthritis (AIA) model is widely used in research to investigate pathogenesis. Hind paw inflammation the main outcome this with high loss of mobility function partly related pain. However, analgesics such as non-steroidal anti-inflammatory drugs or opioid interfere process arthritis, thus reducing their beneficial use model. Therefore, we investigated effect nefopam on development order improve pain management AIA model.Female Lewis rats were randomly divided into two...
<h3>Background</h3> Interstitial lung disease (ILD) is detected until 60% of patients with rheumatoid arthritis (RA), but clinically significant in around 10% cases. It one the leading causes and death RA patients. High levels anti-cyclic citrullinated peptide (CCP) autoantibodies are associated co-occurrence pulmonary [1]. Moreover, fibrosis marker mucine (MUC-1) was described to be a predictive indicator for ILD [2]. The adjuvant-induced (AIA) model commonly used investigate arthritic...
It is now well established that heavy ion radiotherapy can offer some potential merits over the conventional radiotherapy. The advantage of this new treatment modality lies on physical and biological properties carbon ions. provides good dose localization (Bragg peak) in critical cancer tissue gives higher relative effectiveness cell killing. Taking these clinically relevant properties, a high number patient have been treated with ions, results were found to be very promising. With growing...
Biological complications related to bacterial engraftment on rough titanium are an issue in design of new functionalized implants. By fine-tuning femtosecond lasers (FSL) parameters, we aim multiscale (micro- + nano-scale) textured surfaces maintaining osteo-integration with unique antibacterial properties. Titanium samples (Ti6-Al4V) irradiated at 1030-515-257 nm wavelengths produce various types Laser-Induced Periodic Surface Structures (LIPSS). We revealed that LIPSS periodicity and...