David J. Quispe-Parra

ORCID: 0000-0003-4828-0825
Publications
Citations
Views
---
Saved
---
About
Contact & Profiles
Research Areas
  • Echinoderm biology and ecology
  • Marine Bivalve and Aquaculture Studies
  • Wnt/β-catenin signaling in development and cancer

University of Puerto Rico at Río Piedras
2023

University of Puerto Rico System
2020-2021

Abstract Echinoderms comprise a group of animals with impressive regenerative capabilities. They can replace complex internal organs following injury or autotomy. In holothurians sea cucumbers, cellular processes intestinal regeneration have been extensively studied. The molecular machinery behind this faculty, however, remains to be understood. Here we assembled and annotated de novo transcriptome using RNA-seq data consisting regenerating non-regenerating tissues from the cucumber...

10.1038/s41598-020-79436-2 article EN cc-by Scientific Reports 2021-01-11

Wnt signaling has been shown to play multiple roles in regenerative processes, one of the most widely studied which is regeneration intestinal luminal epithelia. Most studies this area have focused on self-renewal stem cells; however, may also more dynamic functions, such as facilitating organogenesis. To explore possibility, we employed sea cucumber Holothuria glaberrima that can regenerate a full intestine over course 21 days after evisceration. We collected RNA-seq data from various...

10.3390/genes14020309 article EN Genes 2023-01-25

La regeneración es un proceso llamativo que permite la reconstitución de miembro u órgano afectado o perdido. en los organismos depende sus características filogenéticas, las cuales permiten agrupación ciertos seres son conocidos por su gran capacidad anatómica como el caso platelmintos y equinodermos. Dentro del grupo equinodermos, pepino mar Holothuria glaberrima organismo modelo poco común tiene regenerar órganos internos. Es invertebrado con desarrollo embriológico similar a vertebrados...

10.18845/tm.v32i8.4570 article ES cc-by-nc-nd Revista Tecnología en Marcha 2019-12-20

Abstract Echinoderms comprise a group of animals with impressive regenerative capabilities. They can replace complex internal organs following injury or autotomy. In holothurians sea cucumbers, cellular processes intestinal regeneration have been extensively studied. The molecular machinery behind this faculty, however, remains to be understood. Here we assembled and annotated de novo transcriptome using RNA-seq data consisting regenerating non-regenerating tissues from the cucumber...

10.1101/2020.09.23.310599 preprint EN cc-by-nd bioRxiv (Cold Spring Harbor Laboratory) 2020-09-24
Coming Soon ...