- Ear Surgery and Otitis Media
- Facial Nerve Paralysis Treatment and Research
- Ear and Head Tumors
- Nasal Surgery and Airway Studies
- Glaucoma and retinal disorders
- Neuroscience of respiration and sleep
- Cardiovascular and Diving-Related Complications
- T-cell and B-cell Immunology
- CAR-T cell therapy research
- Reconstructive Facial Surgery Techniques
- Ophthalmology and Eye Disorders
- Otolaryngology and Infectious Diseases
- Tracheal and airway disorders
- Cerebrospinal fluid and hydrocephalus
- Single-cell and spatial transcriptomics
- Vestibular and auditory disorders
Amgen (United States)
2021
University of Florida
2012-2016
Single-cell RNA sequencing is a powerful tool to examine cellular heterogeneity, novel markers and target genes, therapeutic mechanisms in human cancers animal models. Here, we analyzed single-cell data of T cells obtained from multiple mouse tumor models by PCA-based subclustering coupled with TCR tracking using the STARTRAC algorithm. This approach revealed various differentiated cell subsets activation states, correspondence between tumors. analyses demonstrated peripheral that were...
Objectives To evaluate the efficacy of combined antistaphylococcal and antipseudomonal preoperative antibiotics for preventing surgical site infections following tympanoplasty mastoidectomy with contaminated cholesteatoma. Study Design Retrospective chart review. Methods Medical records patients who underwent ± cholesteatoma were reviewed. Only cases considered to have or dirty fields included. The primary outcome measure was occurrence postoperative infections, perichondritis, pinna...
Objectives: Evaluate the efficacy of combined anti‐staphylococcal and anti‐pseudomonal preoperative antibiotics for preventing surgical site infections following tympanoplasty with mastoidectomy contaminated cholesteatoma. Methods: Retrospective chart review medical records patients who underwent cholesteatoma were reviewed. Only cases considered to have or dirty/infected fields included. The primary outcome measure was postoperative perichondritis, pinna abscess, periotic cellulitis,...
Objectives/Hypothesis Scuba diving may cause severe hearing loss and vertigo due to inner ear barotrauma decompression sickness. These be difficult differentiate clinically. Decompression sickness requires costly potentially dangerous hyperbaric therapy, whereas such treatment worsen barotrauma. The objective of this study was assess the potential utility magnetic resonance imaging identify distinguish blood from air in ear, manifestations sickness, using a guinea pig model. Study Design...
Objectives: Evaluate the efficacy of combined anti‐staphylococcal and anti‐pseudomonal preoperative antibiotics for preventing surgical site infections following tympanoplasty mastoidectomy (TM) with contaminated cholesteatoma. Methods: Study Design: Retrospective chart review Method: Medical records patients who underwent TM cholesteatoma were reviewed. Only cases considered to have or dirty/infected fields included. Patients excluded if there was preexisting infection intraoperative...