A5101566051- Lung Cancer Treatments and Mutations
- Ovarian cancer diagnosis and treatment
- Colorectal and Anal Carcinomas
- Cancer Genomics and Diagnostics
- Head and Neck Cancer Studies
- Acute Lymphoblastic Leukemia research
- Lung Cancer Research Studies
- Lung Cancer Diagnosis and Treatment
- HER2/EGFR in Cancer Research
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Multiple and Secondary Primary Cancers
- Lymphoma Diagnosis and Treatment
- Biosimilars and Bioanalytical Methods
- Meningioma and schwannoma management
- Pancreatic and Hepatic Oncology Research
- Chronic Myeloid Leukemia Treatments
- CAR-T cell therapy research
- COVID-19 and healthcare impacts
- Hematopoietic Stem Cell Transplantation
- Cancer therapeutics and mechanisms
- Neurofibromatosis and Schwannoma Cases
- Breast Cancer Treatment Studies
- Cancer Treatment and Pharmacology
- Bladder and Urothelial Cancer Treatments
- Health Systems, Economic Evaluations, Quality of Life
University of California, Los Angeles
2025
Sardar Patel Medical College
2014-2024
Sarojini Naidu Medical College
2022
Motilal Nehru Medical College
2015
Gujarat Cancer & Research Institute
2011
This multicenter, double-blind, randomized study compared the efficacy, pharmacokinetics (PKs)/pharmacodynamics (PDs), safety and immunogenicity profile of RTXM83 vs. reference rituximab (R-rituximab), both with CHOP, as first-line treatment diffuse large B-cell lymphoma (DLBCL). A total 272 patients <65 years age, good prognosis (136 per arm) were (1:1) to receive six cycles either or R-rituximab. The primary efficacy endpoint was achieved (overall response rate 83.6% for 82.9% R-rituximab)...
Abstract Despite substantial research and drug discovery efforts, Alzheimer’s Disease (AD) remains the sixth leading cause of death in United States, underscoring urgent need for novel therapeutic targets. A mutation clusterin (CLU) gene that hinders expression cyto-protective secreted isoform (sCLU) affects aggregation clearance two key proteins implicated AD, Aβ tau, is third most significant genetic risk factor late-onset AD. Here, we present findings from our program to identify small...
Cancer related fatigue (CRF) is a problem that highly under reported, recognized and thus, treated. About 80% of patients receiving chemotherapy/radiotherapy experience CRF, making it the most common side effect cancer treatment. Functional assessment chronic illness therapy (FACIT-F) version-4 13 item questionnaire has been used to measure level during their daily activities over past 7 days. 92 age 18 years above attending oncology Out Patient Department (OPD) regional center were...
Metastatic lesions to the clivus have been reported in various cancers including lung cancer, prostate carcinoma, skin melanoma, and hepatocellular carcinoma. There only a few reports of breast cancer presenting with isolated clival metastasis. We report case 35-year-old lady, who was known carcinoma presented diplopia as sign The etiology established by magnetic resonance imaging which showed an enhancing lesion clivus. diagnosis metastasis from confirmed transsphenoidal biopsy.
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Acute myeloid leukemia (AML) in elderly patients differs biologically from that younger and is known to have unfavorable chromosomal rearrangements, higher resistance, lower tolerance chemotherapy. In such circumstances, instead of giving full-blown chemotherapy, palliative metronomic chemotherapy (MCT) could be a treatment option.We performed prospective pilot study old AML (age >60 years) not amenable curative treatment. Thirty-two were enrolled into the treated with daily oral...
Ovarian cancer is a leading cause of death from gynecological in the world and India. This study aims to evaluate efficacy toxicity profile oral metronomic chemotherapy (MCT) form etoposide, cyclophosphamide, tamoxifen recurrent metastatic ovarian cancer.
Background: A dramatic improvement in the survival of acute lymphoblastic leukemia (ALL) patients last three decades has been observed. MCP 841 protocol is an old but effective tool with tolerable toxicities. The objective this study was to estimate relapse-free ALL treated uniformly on basis various prognostic factors. Materials and Methods: design retrospective it conducted a regional cancer center Northwest India. Three hundred ten who underwent treatment regular follow-up for up 5 years...
Kikuchi-Fujimoto disease (KFD) is a rare, benign, self-limiting disorder that generally presents with cervical lymphadenopathy. Recognition and early diagnosis of this condition very critical as it can be easily mistaken for tuberculosis, lymphoma or systemic lupus erythematosus. It predominantly affects young adults (mean age 20-30 years), slight preponderance in females. There have been rare reports KFD childhood elderly. We report case 9-year-old female child who presented fever...
Myoepithelioma (ME) is a rarely encountered tumor of salivary gland accounting for about 1% all tumors. Though they were first identified long back, still their histopathologic features and immunohistochemistry (IHC) profile are not well characterized there no definitive criterion this with complex varied remaining major barrier. We present case parotid enlargement in an 18-year-old girl whom the IHC studies superficial parotidectomy specimen revealed positive staining Cytokeratin 5/6, HMW...
Sweet's syndrome (acute febrile neutrophilic dermatosis) is a well documented entity in acute leukemia. However, there have been only rare reports of its association with chronic We report case sweet's patient BCR-ABL positive myelogenous leukemia accelerated phase for association, classical clinical presentation and dramatic therapeutic response to corticosteroids.
Purpose: To compare the compliance, tumor response, quality of life and survival between a hypo-fractionated conventional fractionated RT schedule in locally advanced NSCLC patients. Materials Methods: Total 50 patients with unresectable stage III were given 3 cycle neoadjuvant chemotherapy. After 3-4 weeks completion 3rd cycle, 25 received total 17Gy 2 fr (8.5Gy/fr) on day 1 8 study arm, Gy (2Gy/fr) administered daily (5days/week) for 5 weeks. Disease response was evaluated by RECIST...
Purpose: The purpose of this study was to compare conventional 3 field versus 5 treatment planning techniques during 3-dimensional conformal radiotherapy(3D-CRT) in respect OAR, PTV coverage, response & toxicities head and neck Cancer. Materials methods: This included 50 biopsy proven registered patients cancer. Twenty five randomized each arm. Arm A- 3D- radiotherapy by delivery technique. B--3D- All were irradiated on linear accelerator with concurrent chemotherapy form weekly...