Gregory P. Fricker

ORCID: 0000-0003-4836-7875
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About
Contact & Profiles
Research Areas
  • Streptococcal Infections and Treatments
  • Healthcare Policy and Management
  • Insect symbiosis and bacterial influences
  • Antimicrobial Resistance in Staphylococcus
  • Legume Nitrogen Fixing Symbiosis
  • Hepatitis C virus research
  • Bacterial Identification and Susceptibility Testing
  • Acute Myocardial Infarction Research
  • Chromatin Remodeling and Cancer
  • Emergency and Acute Care Studies
  • Peptidase Inhibition and Analysis
  • Primary Care and Health Outcomes
  • Neurofibromatosis and Schwannoma Cases
  • Hepatitis B Virus Studies
  • Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
  • Cardiac tumors and thrombi
  • Infective Endocarditis Diagnosis and Management
  • Gestational Trophoblastic Disease Studies
  • Coronary Interventions and Diagnostics
  • Liver Disease Diagnosis and Treatment
  • Cardiac Imaging and Diagnostics
  • Nematode management and characterization studies

Massachusetts General Hospital
2023-2025

Harvard University
2023-2025

Vanderbilt University
2017-2021

Emory University
2021

Viral hepatitis remains a major global health issue, with chronic B (HBV) and C (HCV) causing approximately 1 million deaths annually, primarily due to liver cancer cirrhosis. More than 1.5 people contract HCV each year, disproportionately affecting vulnerable populations, including American Indians Alaska Natives (AI/AN). While direct-acting antivirals (DAAs) are highly effective, timely accurate diagnosis challenge, particularly in resource-limited settings. The current two-step testing...

10.1126/sciadv.adt3803 article EN cc-by-nc Science Advances 2025-03-19

Most insects maintain associations with microbes that shape their ecology and evolution. Such symbioses have important applied implications when the associated are pests or vectors of disease. The squash bug, Anasa tristis (Coreoidea: Coreidae), is a significant pest human agriculture in its own right also causes damage to crops due capacity transmit bacterial plant pathogen. Here, we demonstrate complete understanding these requires consideration association symbionts family...

10.3389/fmicb.2021.719112 article EN cc-by Frontiers in Microbiology 2021-10-04

We report the case of a 4-year-old female with primary extradural intramedullary atypical teratoid/rhabdoid tumor (AT/RT) leading to middle cerebral artery (MCA) infarct and Froin's syndrome. She presented 6-pound weight loss over previous week, as well decreased urinary output an altered mental status. underwent brain MRI that revealed left MCA infarct, mild ventriculomegaly, bilateral internal carotid artery, M1, A1 stenosis. An external ventricular drain (EVD) was placed due increased...

10.1159/000481514 article EN Pediatric Neurosurgery 2017-11-01

We conducted a survey of pediatric infectious diseases providers in the Emerging Infections Network regarding workup and treatment children with Staphylococcus aureus bacteremia (SAB). found significant practice variation management SAB. These findings emphasize need for further research to guide best practices.

10.1093/jpids/piy022 article EN cc-by-nc Journal of the Pediatric Infectious Diseases Society 2018-02-06

The current multiday diagnosis and treatment paradigm for hepatitis C virus (HCV) infection results in far fewer patients receiving with direct-acting antiviral agents than those diagnosed HCV infection. To achieve elimination, a shift access to is needed from testing algorithms same-day treatment. This will require new tools, such as point-of-care (POC) antigen tests or nucleic acid B (HBV) human immunodeficiency (HIV) that do not venous blood. also better use of existing resources,...

10.1093/infdis/jiad177 article EN cc-by The Journal of Infectious Diseases 2023-09-22

ABSTRACT Most insects maintain associations with microbes that shape their ecology and evolution. Such symbioses have important applied implications when the associated are pests or vectors of disease. The squash bug, Anasa tristis (Coreoidea: Coreidae), is a significant pest human agriculture in its own right also causes damage to crops due capacity transmit bacterial plant pathogen. Here, we demonstrate complete understanding these requires consideration association symbionts family...

10.1101/2021.07.14.452367 preprint EN cc-by-nc-nd bioRxiv (Cold Spring Harbor Laboratory) 2021-07-14

Background: Disease course following hospitalization for ulcerative colitis (UC) is poorly understood. Here, we evaluate the outcomes of hospitalized patients with UC across Mass General Brigham (MGB) health system over a 25-year period. Methods: We developed and validated natural language processing (NLP) algorithm to derive endoscopic disease severity. included all MGB from 1996-2021 used NLP identify those moderate severe severity, defined according Mayo Score. Cox proportional hazards...

10.2139/ssrn.4579878 preprint EN 2023-01-01
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