About
Contact & Profiles
A5046205229
Research Areas
- Sirtuins and Resveratrol in Medicine
- Amyotrophic Lateral Sclerosis Research
- Autophagy in Disease and Therapy
- PARP inhibition in cancer therapy
- Calcium signaling and nucleotide metabolism
- Quantum Dots Synthesis And Properties
- Neurological diseases and metabolism
- Tryptophan and brain disorders
- Ubiquitin and proteasome pathways
- Nanocluster Synthesis and Applications
- Genetic Neurodegenerative Diseases
- Carbon and Quantum Dots Applications
Macquarie University
2019-2021
UNSW Sydney
2020-2021
The past decade has seen a rapid acceleration in the discovery of new genetic causes ALS, with more than 20 putative ALS-causing genes now cited. These encode proteins that cover diverse range molecular functions, including free radical scavenging (e.g., SOD1), regulation RNA homeostasis TDP-43 and FUS), protein degradation through ubiquitin-proteasome system ubiquilin-2 cyclin F) autophagy (TBK1 sequestosome-1/p62). It is likely various initial triggers disease (either genetic,...
10.3389/fnmol.2021.627740
article
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cc-by
Frontiers in Molecular Neuroscience
2021-04-27
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