A5103501330- Adipose Tissue and Metabolism
- Adipokines, Inflammation, and Metabolic Diseases
- Glioma Diagnosis and Treatment
- Renal function and acid-base balance
- Virus-based gene therapy research
- Dialysis and Renal Disease Management
- Receptor Mechanisms and Signaling
- Lanthanide and Transition Metal Complexes
- RNA regulation and disease
- Neuroendocrine regulation and behavior
- Body Composition Measurement Techniques
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Heart Rate Variability and Autonomic Control
- Central Venous Catheters and Hemodialysis
- Thermoregulation and physiological responses
- Pharmacology and Obesity Treatment
- Metabolism, Diabetes, and Cancer
- Eicosanoids and Hypertension Pharmacology
- Sexual Differentiation and Disorders
- Nanoparticle-Based Drug Delivery
- dental development and anomalies
- Nanoplatforms for cancer theranostics
Université de Strasbourg
2011-2021
Laboratoire de Biophotonique et Pharmacologie
2019
Centre National de la Recherche Scientifique
2010-2011
Hôpital d'Hautepierre
2010-2011
Hôpitaux Universitaires de Strasbourg
2010
Laboratoire de Dynamique des Fluides
2010
The context of the this research is development nanoparticulate systems exhibiting long circulation times in blood pool, loaded with X-ray contrasting compounds, to be used as pool contrast agents computed tomography. This study presents an original, new and simple formulation radiopaque nano-emulsions composed iodinated oil, formed by a spontaneous emulsification method. As result, extremely monodisperse, nano-droplets were generated, ranging size from 20 190 nm, presenting iodine...
X-linked hypohidrotic ectodermal dysplasia (XLHED) is a genetic disorder due to mutation of Eda gene and mainly characterized by an absence or deficient function hair, teeth sweat glands, craniofacial dysmorphologies. Although the tooth abnormalities in Tabby mutant mice -the murine model XLHED- have been extensively studied, characterization complex, especially mandibular morphology has received less attention. From 3D microCT reconstructions left mandible, outline, lateral view, was...
Obesity and the metabolic syndrome are two pathologies whose prevalence in a constant increase. Evaluation of total fat mass but also distribution between visceral subcutaneous adipose tissue important factors while assessing pathophysiology these pathologies. Computed tomography (CT) bioimpedance (BIS) translational methods most frequently used human beings as well rodent models longitudinal studies on adiposity obesity. Surprisingly, no direct comparison micro-CT BIS was reported yet mice....
Imidazoline receptor antisera selected/Nischarin was proposed several years ago as the functional entity for I1 medullary receptors (I1Rs) targeted, together with α2-adrenoceptors, by centrally acting antihypertensive drugs, such clonidine. The objective of this study to test assumption using a pyrroline analog clonidine, LNP599, which, unlike clonidine and related compounds, displays high selectivity toward I1Rs. Cardiovascular effects LNP599 (3 mg/kg intravenous) were evaluated in...