Yusuf Özgür Çakmak

ORCID: 0000-0003-4884-0714
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About
Contact & Profiles
Research Areas
  • Heart Rate Variability and Autonomic Control
  • Vagus Nerve Stimulation Research
  • EEG and Brain-Computer Interfaces
  • Olfactory and Sensory Function Studies
  • Neurological disorders and treatments
  • Cerebrovascular and Carotid Artery Diseases
  • Parkinson's Disease Mechanisms and Treatments
  • Cardiovascular Health and Disease Prevention
  • Neural and Behavioral Psychology Studies
  • Botulinum Toxin and Related Neurological Disorders
  • Neuroscience and Neuropharmacology Research
  • Acupuncture Treatment Research Studies
  • Infant Health and Development
  • Endometriosis Research and Treatment
  • Uterine Myomas and Treatments
  • Transcranial Magnetic Stimulation Studies
  • Healthcare and Venom Research
  • Neuroscience of respiration and sleep
  • Cardiovascular Syncope and Autonomic Disorders
  • Functional Brain Connectivity Studies
  • Sulfur Compounds in Biology
  • Pediatric health and respiratory diseases
  • Sleep and Wakefulness Research
  • Advanced Chemical Sensor Technologies
  • Circadian rhythm and melatonin

University of Otago
2016-2025

MedTech CoRE
2018-2025

Türk Anesteziyoloji ve Reanimasyon Derneği
2023

Brain Research New Zealand
2018-2022

The Centre for Health (New Zealand)
2020-2022

The University of Sydney
2022

The University of Western Australia
2019

University of Auckland
2019

Intelligent Systems Research (United States)
2019

Biomechanics Institute of Valencia
2019

One of the critical factors that guide choice behavior is prior bias decision-maker with respect to different options, namely, relative readiness by which opts for a specific choice. Although previous neuroimaging work has shown decision related activity in orbitofrontal cortex, intraparietal sulcus (IPS) and dorsolateral prefrontal recent Javadi et al. (2015), primary motor cortex was also implicated. By applying transcranial direct current stimulation (tDCS), they have revealed causal role...

10.3389/fnins.2018.00410 article EN cc-by Frontiers in Neuroscience 2018-06-18

Vagus nerve stimulation (VNS) has become a well-established therapy for epilepsy and depression, is emerging to treat inflammatory disease, with the cervical vagus (CVN) as major site. CVN morphometries are missing VNS, considering its variability. Morphometric data were obtained from CVNs in 27 cadavers, including branching patterns histology. Cross-sectional area, greater lesser diameters averaged 7.2 ± 3.1 mm2, 5.1 1.5 4.1 1.3 mm, ≤11.0 ≤7.0 ≤5.8 mm 90% of specimens, respectively. Midline...

10.1038/s41598-018-26135-8 article EN cc-by Scientific Reports 2018-05-16

Most dorsal thalamic nuclei send axons to specific areas of the neocortex and sectors reticular nucleus; then sends reciprocal connections back same nucleus, directly as well indirectly through a relay in nucleus. This can be regarded 'canonical' circuit sensory thalamus. For pathways that link thalamus hippocampal formation, only few comparable have been described. The reuniens nucleus some its major cortical efferents formation. present study shows cells formation are retrogradely labelled...

10.1111/j.1469-7580.2008.00858.x article EN Journal of Anatomy 2008-01-25

ABSTRACT Introduction Neuromodulation of cortical brain regions associated with the gut‐brain axis may have potential to modulate gastric function. Previous studies shown phase‐amplitude coupling between electroencephalogram (EEG) alpha band frequency insula (Ins) and slow wave (GSW) activity. This study investigated first evidence EEG‐neurofeedback (EEG‐NF) training explore its effects on GSW activity heart rate variability (HRV). Methods A randomized crossover design was employed 20...

10.1111/nmo.15009 article EN cc-by-nc-nd Neurogastroenterology & Motility 2025-02-17

Auricular vagal nerve stimulation (AVNS) is an evolving neuromodulation technology that has a wide range of therapeutic applications across multiple disciplines medical science. To date, AVNS results had been interpreted in the context monolog concept auricular branch vagus (ABVN): this sole network mechanism action and/or structure area activations brainstem nuclei, including nucleus tractus solitarius (NTS), locus coeruleus (LC), trigeminal and cuneatus. This review considers overlooked...

10.3389/fnhum.2019.00421 article EN cc-by Frontiers in Human Neuroscience 2019-12-12

In contrast to the rapid advancements in mesoscale connectomic mapping of mammalian brain, similar peripheral nervous system has remained challenging due body's size and complexity. Here, we present a high-speed blockface volumetric imaging with an optimized workflow whole-body clearing, capable entire adult mouse at micrometer resolution within 40 hours. Three-dimensional reconstruction individual spinal fibers Thy1-EGFP mice reveals distinct morphological features sensory motor projections...

10.1101/2025.01.22.632569 preprint EN bioRxiv (Cold Spring Harbor Laboratory) 2025-01-24

Transcutaneous electrical nerve stimulation (TENS) has been a commonly used modality to relieve aches and pain for over 40 years. Commercially available devices provide multiple therapy modes involving different combination of frequency pulse width with intensity. While sets sensation, intensity helps determine tolerability, longer is reported induce feeling deeper stimulation. In fact, empirically shown deliver current into tissues, but in context other modalities. The goal this study was...

10.3389/fpain.2025.1526277 article EN cc-by Frontiers in Pain Research 2025-04-17

In past literature on animal models, invasive vagal nerve stimulation using high frequencies has shown to be effective at modulating the activity of olfactory bulb (OB). Recent advances in humans, despite previous findings used low frequency and found no effect functioning. The present article aimed test potential effects non-invasive, with supplementary exploration orbitofrontal cortex near-infrared spectroscopy (NIRS). Healthy, male adult participants (n = 18) performed two tests [odor...

10.3389/fnins.2018.00225 article EN cc-by Frontiers in Neuroscience 2018-04-24

The jugular venous (JV) pressure waveform is a non-invasive, proven indicator of cardiovascular disease. Conventional clinical methods for assessing these waveforms are often overlooked because they require specialised expertise, and invasive expensive to implement. Recently, image-based have been used quantify JV pulsation on the skin as an indirect way estimating waveforms. However, existing cannot explicitly measure deformations rely use photoplethysmography (PPG) devices identification...

10.1038/s41598-018-35483-4 article EN cc-by Scientific Reports 2018-11-16

The subthalamic nucleus (STN) is important for normal movement as well in disorders. STN a target nuclei patients with advanced Parkinson's disease (PD). Deep brain stimulation (DBS) standard surgical treatment PD. Although DBS results significant reduction motor disability, several negative side effects have been reported. Thus, to understand the of connection should be known. Therefore, present study aims re‑examine an emphasis on poorly‑ or un‑documented connections. Furthermore,...

10.21307/ane-2018-023 article EN Acta Neurobiologiae Experimentalis 2018-01-01

The perception of body ownership creates a sense embodiment, which can be powerful learning tool. Embodied occur by watching an individual's movement and also via human-computer interactions, such as virtual reality (VR) augmented (AR). In this article, we designed implemented novel body-ownership AR/VR tool for human anatomy-the muscular arm avatar (HMAA). HMAA utilizes embodiment-based to explore the hand/forearm musculature. was trialed with medical students extent it could used aid...

10.1109/tlt.2020.2995163 article EN cc-by IEEE Transactions on Learning Technologies 2020-05-18

Abstract Decisions are made based on the integration of available evidence. The noise in evidence accumulation leads to a particular speed–accuracy tradeoff decision-making, which can be modulated and optimized by adaptive decision threshold setting. Given effect pre-SMA activity striatal excitability, we hypothesized that inhibition would lead higher thresholds an increased accuracy bias. We used offline continuous theta burst stimulation assess transient right processes free-response...

10.1162/jocn_a_01134 article EN Journal of Cognitive Neuroscience 2017-04-07

Background: Deep brain stimulation of the subthalamic nucleus (STN-DBS) and pedunculopontine (PPN) significantly improve cardinal motor symptoms postural instability gait difficulty, respectively, in Parkinson's disease (PD). Objective Hypothesis: Intrinsic auricular muscle zones (IAMZs) allow potential to simultaneously stimulate C2 spinal nerve, trigeminal facial sympathetic parasympathetic nerves addition providing feedback control areas including STN, PPN mesencephalic locomotor regions....

10.3389/fnhum.2017.00338 article EN cc-by Frontiers in Human Neuroscience 2017-06-28
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