- Natural product bioactivities and synthesis
- Landslides and related hazards
- Biological Stains and Phytochemicals
- Pharmacological Effects of Natural Compounds
- Molecular Biology Techniques and Applications
- Gout, Hyperuricemia, Uric Acid
- Endoplasmic Reticulum Stress and Disease
- Rock Mechanics and Modeling
- Structural Response to Dynamic Loads
- Sepsis Diagnosis and Treatment
- Biochemical Analysis and Sensing Techniques
- Traditional Chinese Medicine Analysis
- Simulation-Based Education in Healthcare
- Natural Antidiabetic Agents Studies
- Cultural Heritage Materials Analysis
- Plant-Derived Bioactive Compounds
- Ginseng Biological Effects and Applications
- Hops Chemistry and Applications
- PARP inhibition in cancer therapy
- Osteoarthritis Treatment and Mechanisms
- Emergency and Acute Care Studies
- Animal Nutrition and Physiology
- Geophysical Methods and Applications
- Rheumatoid Arthritis Research and Therapies
- Inflammasome and immune disorders
Guiyang College of Traditional Chinese Medicine
2020-2025
Anshun University
2024-2025
Guizhou University
2020-2025
People's Liberation Army 401 Hospital
2025
Affiliated Hospital of Guizhou Medical University
2024
Hangzhou Xixi hospital
2024
Zhejiang University
2024
Zhejiang Chinese Medical University
2024
The First People's Hospital of Xiaoshan District, Hangzhou
2024
Wenzhou Medical University
2024
The study aimed to elucidate the effective chemical composition and molecular mechanism of rheumatoid arthritis (RA) treatment with Jishe Qushi capsules (JSQS) perform clinical validation. components were screened by a database. We used Cytoscape software construct key target-RA composite target network JSQS. Gene Ontology biofunctional analysis Kyoto encyclopedia Genes Genomes (KEGG) pathway enrichment performed for targets, followed docking validation core targets. Ninety-nine patients...
Abstract BACKGROUND: Liver hepatocellular carcinoma (LIHC) exhibits a notable prevalence and fatality rate, posing significant risk to human well-being. 1 . The orphan cytokine receptor-like factor 3 (CRLF3), which evolutionary conservation, has been associated with hematopoiesis in vertebrates, diseases, neuroprotection insects 2,3 However, there is dearth of research investigating the role CRLF3 LIHC underlying mechanisms involved. METHODS: researchers utilized TCGA database examine...
The propagation characteristics of blast waves and the prediction accuracy vibration velocities along negative slopes are important because those can be used to guide engineering application theoretical research. In this paper, wave theory was applied better understand mechanism slopes. Regression analysis for Sadovsky CRSRI velocity models during on-site operations. magnification peak a slope introduced determine threshold altitude difference effect occur. Based on parameter, relative...
It is very important to study the influence of water content on mechanical properties coal rock prevent burst and roadway instability under dynamic disturbance. In this study, split Hopkinson pressure bar (SHPB) test system was applied conduct three-dimensional static impact tests natural water-saturated samples at different strain rates determine a series water-bearing samples. Based new data, we discuss strength, deformation, crushing energy dissipation, fractal characteristics saturated...
Traditionally, C. sappan medicine was the heartwood, which needs to be cut down as a whole. In this research, antitumor activity and mechanisms of leaves stems were compared with roots Caesalpinia sappan; it in order investigate whether could used replace heartwood for treatment, thereby reducing resource destruction.MTT assays identify active sites based on application human liver cancer (HuH-7) cells. High-performance liquid chromatography (HPLC) analyze polar extracts. We also established...
Aim: This study sought to clarify the mechanism of action Miao medicine Tongfengting decoction in treatment gout through network pharmacology and molecular docking by searching for its key targets related pathways. Methods: The active ingredients Decoction were obtained from TCMSP data platform, searched relevant databases gout-related targets,using String Cytoscape 3.9 build a “compound-cross-target-disease” diagram,performed gene ontology (GO) Kyoto encyclopedia genes genomes (KEGG)...
Purpose: To determine the mechanism of action Tripterygium wilfordii Hook F (TwHF) in treatment rheumatoid arthritis (RA) based on network pharmacology and molecular docking. 
 Methods: The active constituents targets TwHF were screened by searching TCMSP, TCMIP, PharmMapper database, BATMAN-TCM platform combined with oral bioavailability drug-like analysis. drug-component-target maps drawn using UniProt database Cytoscape 3.9.0 software. drug-target searched GeneCards, OMIM, TTD,...
Abstract Clinical pharmacists are indispensable providers of emergency medical services. However, the training Chinese clinical in skills is apparently insufficient. The current study aimed to evaluate effect “Warrior” simulator application education pharmacy students (CP students). system, which contains a pharmacokinetics/pharmacodynamics-linked model and drug database, was successfully employed train CP improve their capability deal with various situations. Both an objective (in-class)...
To screen active sites from roots, stems, and leaves of Caesalpinia minax study its antitumor effect.Human liver cancer HuH-7 cells were used to the C. by MTT assay, polar extracts analyzed high-performance liquid chromatography (HPLC). The medicated serum prepared rats was investigate effect on proliferation Hepa 1-6 mouse hepatoma cells. H22 hepatoma-bearing mice model established treated with petroleum ether extract stems (HY②) intraperitoneal injection (20, 60 mg·kg-1) intragastric (100,...
Some ancient murals were found to be repainted on the surface of original form multi-layer murals. The patterns layer are great significance for studying social and cultural behavior in that time. hyperspectral imaging covers visible near-infrared bands, which has advantages information extraction Therefore, a method study transmission performance simulated mural samples is proposed. By making samples, mineral pigment painted covered with 0-11 different layers lime water. Then collected...