Ahmet Gökçe

ORCID: 0000-0003-4895-8958
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About
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Research Areas
  • Sexual function and dysfunction studies
  • Urinary Bladder and Prostate Research
  • Hormonal and reproductive studies
  • Urological Disorders and Treatments
  • Prostate Cancer Diagnosis and Treatment
  • Sperm and Testicular Function
  • Genital Health and Disease
  • Urologic and reproductive health conditions
  • Pediatric Urology and Nephrology Studies
  • Male Reproductive Health Studies
  • Pelvic floor disorders treatments
  • Sexual Differentiation and Disorders
  • Sexuality, Behavior, and Technology
  • Urinary and Genital Oncology Studies
  • Renal and Vascular Pathologies
  • Obstructive Sleep Apnea Research
  • Nigella sativa pharmacological applications
  • Chemotherapy-induced organ toxicity mitigation
  • Bladder and Urothelial Cancer Treatments
  • Prostate Cancer Treatment and Research
  • Menopause: Health Impacts and Treatments
  • Hernia repair and management
  • Kidney Stones and Urolithiasis Treatments
  • Reproductive Health and Technologies
  • Reproductive Biology and Fertility

Sakarya University
2014-2023

Sakarya Eğitim ve Araştırma Hastanesi
2017-2019

Tulane University
2012-2016

University of New Orleans
2012-2014

Erciyes University
2008-2012

Mustafa Kemal University
2009-2012

Sivas Cumhuriyet Üniversitesi
1994

Thymoquinone is the major active component derived from Nigella sativa. Methotrexate a folic acid antagonist widely used in clinic. Aim of this study was to investigate possible protective role thymoquinone on testicular toxicity methotrexate. Experiments were performed male C57BL/6 mice (6 weeks old, 20 ± 2 g). The animals divided into four groups with six each group. Equivalent volumes saline injected intraperitoneally (i.p.) control In group, received i.p. dose 10 mg/kg/day for 4 days....

10.1177/0960327110382564 article EN Human & Experimental Toxicology 2010-09-02

Peyronie's disease (PD) is a localized connective tissue disorder that involves the tunica albuginea (TA) of penis. While surgical correction remains gold standard, search for an effective and less invasive therapy continues. The objective this study was to evaluate effects intratunical injection adipose tissue-derived stem cells (ADSCs) prevention treatment erectile dysfunction in rat model PD. Twenty-four male Sprague-Dawley rats (300-350 g) were randomly divided into four groups: sham,...

10.1111/j.2047-2927.2013.00181.x article EN Andrology 2014-02-24

<i>Objectives:</i> To investigate the protective role of thymoquinone (TQ) on unilateral testicular ischemia-reperfusion (I/R) injury in mice. <i>Materials and Methods:</i> Experiments were performed male C57BL/6 mice (8 weeks old, 20–25 g). The animals divided into 3 groups including 6 each group: control (sham), torsion/detorsion (TD) TD+TQ. Mice, except sham-operated group, subjected to left torsion (720° rotation clockwise direction). experiments finished after...

10.1159/000318890 article EN Urologia Internationalis 2010-01-01

No AccessJournal of UrologyInvestigative Urology1 Sep 2015Transforming Growth Factor-β1 Induced Urethral Fibrosis in a Rat Model Premsant Sangkum, Ahmet Gokce, Ronny B.W. Tan, Mostafa Bouljihad, Hogyoung Kim, Sree Harsha Mandava, Sarmad N. Saleem, George F. Lasker, Faysal A. Yafi, Zakaria Y. Abd Elmageed, Krishnarao Moparty, Suresh C. Sikka, Asim B. Abdel-Mageed, and Wayne J.G. Hellstrom SangkumPremsant Sangkum , GokceAhmet Gokce TanRonny Tan BouljihadMostafa Bouljihad KimHogyoung Kim...

10.1016/j.juro.2015.02.014 article EN The Journal of Urology 2015-02-10

Phosphodiesterase-5 inhibitors (PDE5i, sildenafil, vardenafil, tadalafil and avanafil) are a first-line medical therapy for erectile dysfunction (ED). In all likelihood, PDE5i usage will increase because sildenafil (Viagra® Revatio®) (Cialis® Adcirca®) have recently been recommended as patients with pulmonary hypertension (PH). exhibit higher plasma concentrations when co-administered cytochrome P (CYP) 3A inhibitors, which influences their side-effect profile. The concentrations, caused by...

10.2174/138920013804870600 article EN Current Drug Metabolism 2013-01-21

Study Type – Therapy (RCT) Level of Evidence 1b What’s known on the subject? and What does study add? Several authors have reported their experience with PDE5 inhibitors alone or in combination selective serotonin re‐uptake for treating premature ejaculation. However, to our knowledge, this is first laboratory design evaluate effects three throughout ejaculation process men lifelong In setting seem prolong ELT but difference from placebo significant only vardenafil. The quality penile...

10.1111/j.1464-410x.2010.09646.x article EN BJU International 2010-09-07

The aim of this study was to evaluate interrelation left varicocoele with height, body mass index (BMI) and sperm counts. We retrospectively evaluated the data all patients who consulted for infertility at a tertiary academic referral centre from 2000 2010. Patient's weight, BMI, semen analysis, presence or absence side grade were evaluated. In statistical evaluations chi-square, student's t, Mann-Whitney U, anova logistic regression analyses performed. analyses, Bonferroni post hoc test...

10.1111/j.2047-2927.2012.00014.x article EN Andrology 2012-10-09

Guy's Stone Score and S.T.O.N.E. Nephrolithometry nomograms have been introduced for systematic quantitative assessment of kidney stones. The aim this study was to reveal the value two scorings systems, Guy S.T.O.N.E, most frequently used predicting postoperative stone-free status prior Percutaneous Nephrolithotomy (PCNL), in prediction results PCNL.We retrospectively examined patients who underwent PCNL. Preoperative abdominopelvic computerized tomography images these were reviewed scored...

10.5173/ceju.2015.552 article EN Editor-in-Chief s Voice List of Authors is an Important Element in a Scientific Publication 2015-01-01

Although a large number of studies report the impact daily exercise on many aspects women's health, none them address relationship between Pilates and sexual function prospectively. The aim this study was to assess effect in healthy young women using validated questionnaire. In total, 34 premenopausal Turkish aged 20 50 years who had regular menstrual cycles relationships were included study. Women asked complete Beck Depression Inventory (BDI) Female Sexual Function Index (FSFI)...

10.1080/0092623x.2015.1033576 article EN Journal of Sex & Marital Therapy 2015-03-31

Introduction. Cyclosporine A, an immunosuppressive agent, is widely used after organ transplantation such as the liver and kidney. However, its widespread use restricted because it has serious toxic effects on Caffeic acid phenethyl ester (CAPE) a natural product with potent anti-inflammatory, antitumor, antioxidant activities, attenuates inflammation lipid peroxidation induced by ischemia-reperfusion injury. The purpose of present study was to investigate CAPE cyclosporine A (CsA)-induced...

10.3109/08860220903137517 article EN Renal Failure 2009-10-01

Recurrent urinary tract infections are important in children and adults with diabetes mellitus and/or incontinence due to risk of pyelonephritis (PYN) renal damage. There is a positive correlation released free radicals during PYN Experimental studies showed that antioxidant agents improve damage when used immediately after bacterial inoculation.The aim the present study was evaluate whether treatment by thymoquinone (TQ) before or Escherichia coli inoculation prevents oxidative acute an...

10.1016/j.curtheres.2011.09.002 article EN publisher-specific-oa Current Therapeutic Research 2011-10-01

ABSTRACT: The inheritance of varicoceles and the potential transmission to first‐degree relatives has rarely been investigated. In present study, we examined men with known varicocele reveal familial risk for varicocele. Of patients clinical who presented infertility, testicular pain, or asymmetrical swelling scrotum between June 1, 2008 May 31, 2009, 49 agreed have their available contacted screening (n = 66). A cohort 100 consecutive applied department internal medicine 2009 checkup...

10.2164/jandrol.109.008698 article EN Andrology 2010-05-06

Methotrexate is used to treat certain types of cancer the breast, skin, head and neck, or lung. can cause serious life-threatening side effects on liver, lungs, kidneys, immune system. chemotherapy causes testicular damage in humans. The aim this study was investigate possible protective role erdosteine toxicity methotrexate mice. Twenty-six male mice were divided into four groups as follows: group 1, control; 2, erdosteine-treated; 3, methotrexate-treated; 4, + treated. On first day...

10.1177/0748233710369666 article EN Toxicology and Industrial Health 2010-05-26

Various studies have been reported to predict the success of varicocelectomy. Neutrophil-lymphocyte ratio (NLR) is a frequently used indicator systemic inflammation. We aimed evaluate effect inflammation on varicocelectomy using NLR. The data 86 patients who underwent for infertility were evaluated retrospectively. Pre-operative demographic characteristics patients, laboratory results such as haemogram, and semen analysis clinical recorded. with highest total motile sperm count was accepted...

10.1111/and.13188 article EN Andrologia 2018-11-05

Objective:The aim of this study was to present outcomes our patients who had undergone retrograde intrarenal surgery (RIRS) with fluoroscopy-free technique and evaluate the efficacy safety technique. Material methods:Between January 2013 June 2015 93 RIRS were retrospectively evaluated.Our involved preoperative assessment ureter by semi-rigid ureteroscope, inserting guidewire through ureteral access sheath over visiual guidance passing flexible ureteroscope sheath, dusting stone holmium...

10.5152/tud.2017.24638 article EN Turkish journal of urology 2017-08-01
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